Results 41 to 50 of about 13,741 (226)

Deformation of the Outer Hair Cells and the Accumulation of Caveolin-2 in Connexin 26 Deficient Mice. [PDF]

PLoS ONE, 2015
Mutations in GJB2, which encodes connexin 26 (Cx26), a cochlear gap junction protein, represent a major cause of pre-lingual, non-syndromic deafness. The degeneration of the organ of Corti observed in Cx26 mutant-associated deafness is thought to be a ...
Takashi Anzai, Ichiro Fukunaga, Kaori Hatakeyama, Ayumi Fujimoto, Kazuma Kobayashi, Atena Nishikawa, Toru Aoki, Tetsuo Noda, Osamu Minowa, Katsuhisa Ikeda, Kazusaku Kamiya   +10 more
doaj   +1 more source

Fas Ligand Expression in the Organ of Corti [PDF]

Audiology and Neurotology, 2003
We have previously demonstrated by FACS analysis and histochemistry that Fas ligand (FasL) increases on cochlear cell surfaces after immune response or stimulation with γ-interferon (IFN-γ). To determine whether the appearance of FasL on cochlear cell membranes is related to gene expression or to posttranslational events, cochlear cells were treated ...
Bodmer, Daniel, Brors, Dominik, Bodmer, Morana, Pak, Kwang, Ryan, Allen F.   +4 more
openaire   +3 more sources

A perspective from the Mesozoic: Evolutionary changes of the mammalian skull and their influence on feeding efficiency and high‐frequency hearing

The Anatomical Record, EarlyView.
Abstract The complex evolutionary history behind modern mammalian chewing performance and hearing function is a result of several changes in the entire skeletomuscular system of the skull and lower jaw. Lately, exciting multifunctional 3D analytical methods and kinematic simulations of feeding functions in both modern and fossil mammals and their ...
Julia A. Schultz
wiley   +1 more source

Cochlear duct length along the outer wall vs organ of corti: Which one is relevant for the electrode array length selection and frequency mapping using Greenwood function?

World Journal of Otorhinolaryngology-Head and Neck Surgery, 2019
Cochlear duct length (CDL) measurement or estimation is a hot topic for various research groups in the cochlear implant (CI) field as of today. Getting the CDL along the outer wall (LW) and organ of corti (OC) is possible but considering the clinical ...
Anandhan Dhanasingh
doaj   +1 more source

Are there morpho‐acoustic patterns of adaptation in nonhuman primate ears? Testing the role of ecology and habitat in shaping ear morphology and function

The Anatomical Record, EarlyView.
Abstract Analysis of the variation in the bony structures of the inner and middle ear provides critical insights into functional morphology, as well as adaptive morphology across primates. In this study, we investigated whether ear morphology patterns are related to the ecological characteristics of species and their habitats to test two acoustic ...
Myriam Marsot, Rémi Laffont, Émilie Steimetz, Patricia Balaresque, Sébastien Couette   +4 more
wiley   +1 more source

Metabolic Abnormalities Linked to Auditory Pathways in ApoE-Knockout HEI-OC1 Cells: A Transcription-Metabolism Co-Analysis

Biomolecules, 2022
Lipid transporter protein apolipoprotein E (APOE) has contributed to functional studies of various organ functions. Animals with ApoE knockout (KO) have been used to study atherosclerosis and hyperlipidemia while an increasing number of researchers have ...
Lu Ma, Hongshun Wang, Jun Yao, Qinjun Wei, Xin Cao   +4 more
doaj   +1 more source

New techniques for old bones: Morphometric and diffeomorphometric analysis of the bony labyrinth of the Reilingen and Ehringsdorf Neandertals

The Anatomical Record, EarlyView.
Abstract Neandertals are known to possess very distinctive traits in their bony labyrinth morphology, such as an inferiorly positioned posterior canal and a very low number of turns in the cochlea. Hence, the inner ear has been often used to assess the Neandertal status of fragmentary fossils.
Alessandro Urciuoli, Julia Diez‐Valero, Ignacio Martínez, Rolf Quam, Brian A. Keeling, Nicole M. Webb, Mercedes Conde‐Valverde   +6 more
wiley   +1 more source

Morphology of the monotreme organ of Corti and macula lagena

, 1996
The organ of Corti and macula lagena were studied by scanning and transmission electron microscopy in two species of monotreme, the platypus and echidna.
Pickles J.O., Ladhams A.
core   +1 more source

Orchard netting impacts on biodiversity leading to cascading effects at the ecosystem level

Biological Reviews, EarlyView.
ABSTRACT Agriculture must ensure food production without further compromising the ecosystem functions upon which it depends. Agricultural practices should therefore avoid harming farmland biodiversity, especially of taxa that supply the key ecosystem services (e.g.
Corrado Alessandrini, Karan Sethi, Emanuela Granata, Ekaterina Mogilnaia, Valeria Vitangeli, Giovanni Zanfei, Chiara Fedrigotti, Paolo Biella, Dino Scaravelli, Luigi Marchesi, Péter Batáry, Diego Rubolini, Paolo Pedrini, Mattia Brambilla   +13 more
wiley   +1 more source

ILDR1 deficiency causes degeneration of cochlear outer hair cells and disrupts the structure of the organ of Corti: a mouse model for human DFNB42

Biology Open, 2015
Immunoglobulin-like domain containing receptor 1 (ILDR1) is a poorly characterized gene that was first identified in lymphoma cells. Mutations in ILDR1 are responsible for DFNB42, but the pathogenesis of hearing loss caused by ILDR1 mutations remains to ...
Qing Sang, Wen Li, Yao Xu, Ronggui Qu, Zhigang Xu, Ruizhi Feng, Li Jin, Lin He, Huawei Li, Lei Wang   +9 more
doaj   +1 more source