Results 61 to 70 of about 36,422 (226)
The Anatomical Record, EarlyView.Abstract Neandertals are known to possess very distinctive traits in their bony labyrinth morphology, such as an inferiorly positioned posterior canal and a very low number of turns in the cochlea. Hence, the inner ear has been often used to assess the Neandertal status of fragmentary fossils.
Alessandro Urciuoli +6 more
wiley +1 more source
Biology Open, 2015 Immunoglobulin-like domain containing receptor 1 (ILDR1) is a poorly characterized gene that was first identified in lymphoma cells. Mutations in ILDR1 are responsible for DFNB42, but the pathogenesis of hearing loss caused by ILDR1 mutations remains to ...
Qing Sang +9 more
doaj +1 more source
Targeted deletion of Sox10 by Wnt1-cre defects neuronal migration and projection in the mouse inner ear. [PDF]
PLoS ONE, 2014 Sensory nerves of the brainstem are mostly composed of placode-derived neurons, neural crest-derived neurons and neural crest-derived Schwann cells. This mixed origin of cells has made it difficult to dissect interdependence for fiber guidance. Inner ear-
YanYan Mao +3 more
doaj +1 more source
Role of SoxE transcription factors in development and disease
Developmental Dynamics, EarlyView.Abstract Sox8, Sox9, and Sox10 arose by multiple rounds of genome duplications from a single SoxE gene in ancestral vertebrates. In this review, we will briefly discuss the molecular structure and function of SoxE transcription factors and their evolutionary origin. We will then discuss their expression, function, and developmental disorders.
Merin Lawrence, Gerhard Schlosser
wiley +1 more source
Short-term synaptic plasticity regulates the level of olivocochlear inhibition to auditory hair cells [PDF]
, 2011 In the mammalian inner ear, the gain control of auditory inputs is exerted by medial olivocochlear (MOC) neurons that innervate cochlear outer hair cells (OHCs).
Ballestero, Jimena Andrea +5 more
core +1 more source
Deficiency of angulin-2/ILDR1, a tricellular tight junction-associated membrane protein, causes deafness with cochlear hair cell degeneration in mice. [PDF]
PLoS ONE, 2015 Tricellular tight junctions seal the extracellular spaces of tricellular contacts, where the vertices of three epithelial cells meet, and are required for the establishment of a strong barrier function of the epithelial cellular sheet.
Tomohito Higashi +3 more
doaj +1 more source
The Laryngoscope, EarlyView.Otogenic route of meningitis was associated with greater cochlear hair cell loss in comparison with the meningogenic one in this otopathology study. Neuronal depletion has been traditionally implicated in failed hearing rehabilitation of post‐meningitis deafness.
Matheus Pedrosa Tavares +5 more
wiley +1 more source
Nanoparticle drug delivery systems for inner ear therapy: An overview [PDF]
, 2017 open7noembargoed_20180701Valente, Filippo; Astolfi, Laura; Simoni, Edi; Danti, Serena; Franceschini, Valeria; Chicca, Milvia; Martini, AlessandroValente, Filippo; Astolfi, Laura; Simoni, Edi; Danti, Serena; Franceschini, Valeria; Chicca, Milvia; Martini,
Astolfi, Laura +6 more
core +2 more sources
Use of scanning electron microscopy in the cochlea of guinea pigs
Brazilian Journal of Otorhinolaryngology, 2020 Introduction: The use of electron microscopy in the study of the inner ear has allowed us to observe minute details of the hair cells, especially in ototoxicity studies; however, the preparation of this material is a difficult and delicate task.
Luiz César Nakao Iha +1 more
doaj +1 more source
Behavioral characteristics in sensing mechanism of the Corti
Computational and Structural Biotechnology Journal, 2023 Some experiments can’t be realized because the cochlea’s Corti is the most delicate and complex sensory organ. In this paper, some typical and special behavioral characteristics in the process of sensation were found in medical clinic.
Junyi Liang +4 more
doaj +1 more source