Results 61 to 70 of about 166,078,283 (220)

Role of SoxE transcription factors in development and disease

Developmental Dynamics, EarlyView.
Abstract Sox8, Sox9, and Sox10 arose by multiple rounds of genome duplications from a single SoxE gene in ancestral vertebrates. In this review, we will briefly discuss the molecular structure and function of SoxE transcription factors and their evolutionary origin. We will then discuss their expression, function, and developmental disorders.
Merin Lawrence, Gerhard Schlosser
wiley   +1 more source

Triggered Calcium Lightning Programs Cochlear Development

Exploration, EarlyView.
Summary: Before the onset of hearing, the developing inner ear generates spontaneous calcium signals that are thought to guide maturation. In this study, we discovered a rapid and widespread calcium flash—dubbed “Ca2+ lightning”—originating from supporting cells beneath the sensory hair cells, which triggers coordinated calcium waves across the entire ...
Qiang Ma, Hai‐Peng Wang, Yu‐Meng Jiang, Ke Lai, Ming‐Xian Li, Zhen Zhang, Li‐Na Gong, Jing‐Wei Lai, Kai‐Ming Su, Lu‐Yang Wang, Hui Wang, Shan‐Kai Yin, Hao He, Hai‐Bo Shi   +13 more
wiley   +1 more source

Morphology of the monotreme organ of Corti and macula lagena

, 1996
The organ of Corti and macula lagena were studied by scanning and transmission electron microscopy in two species of monotreme, the platypus and echidna.
Pickles J.O., Ladhams A.
core   +1 more source

Use of scanning electron microscopy in the cochlea of guinea pigs

Brazilian Journal of Otorhinolaryngology, 2020
Introduction: The use of electron microscopy in the study of the inner ear has allowed us to observe minute details of the hair cells, especially in ototoxicity studies; however, the preparation of this material is a difficult and delicate task.
Luiz César Nakao Iha, Oswaldo Laércio Mendonça Cruz   +1 more
doaj   +1 more source

The regulation of stem cell fate and its application in neural regeneration

Interdisciplinary Medicine, EarlyView.
Regulating stem cell fate is crucial for neural regeneration. This review summarizes key physical, biological, and chemical strategies and their applications in repairing nerve injuries, providing new insights for regenerative medicine. Abstract Regulating the fate of stem cells (SCs) is a key technical problem in the field of regenerative medicine and
Yuexin He, Xingyu Chen, Minghong He, Zhe Li   +3 more
wiley   +1 more source

Predicting cochlear structural alterations from auditory function in age‐related hearing loss mice based on optical coherence tomography

Journal of Intelligent Medicine, EarlyView.
Abstract With global population aging, age‐related hearing loss has become a major public health concern. Understanding the relationship between auditory functional decline and cochlear structural degeneration is essential for early detection and precise intervention.
Shu Zheng, Zhiqi Li, Junyue Wang, Guangjian Ni   +3 more
wiley   +1 more source

Force Transmission in the Organ of Corti Micromachine [PDF]

, 2010
Auditory discrimination is limited by the performance of the cochlea whose acute sensitivity and frequency tuning are underpinned by electromechanical feedback from the outer hair cells.
Jong-Hoon Nam, Robert Fettiplace, Nam, Jong-Hoon, Fettiplace, Robert   +3 more
core   +1 more source

Soil health assessment using buried cotton underpants with the help of 1000 citizen scientists

PLANTS, PEOPLE, PLANET, EarlyView.
Soil is a vital resource for life on Earth. Although many soils are degraded, societal awareness of soil‐related issues is limited. To highlight soil as a key resource and fascinating study system, we initiated a citizen science project together with 1000 participants investigating soil health across Switzerland using buried cotton underpants.
S. Franz Bender, Diane Bürge, Luca Bragazza, Eva Knop, Sandie Masson, Noemi Peter, Romina Demarmels, Daniel Mueller, Ariane Imhof, Pia Viviani, Atlant Bieri, Frank Liebisch, Stefan Geisen, Yann Hautier, Panos Panagos, Pablo Garcia‐Palacios, Marta Goberna, David Johnson, Simon Jöhr, Alain Valzano‐Held, Claudia Weik, Nadine Gloor, Heidi Aguilar, Marco Agustoni, Barbara Albertoni, Regina Anderson, Alberto Andreani, Bénédicte Arguillère, Osvaldo Arrigo, Barbara Auer, Vanessa Badà, Brigitte Baenteli, Gaëlle Balleys, Dagmar Bay, Daniel Beck, Martina Becker, Alma Bender‐Freisinger, Sarah Benoit, Barbara Bernasconi, Chiara Bernasconi, Marco Bertschinger, Michael Bessard, David Bichsel, David Bichsel, Matteo Binda, Joel Bischof, Ruth Bischof, Bernadette Bisig, Andreas Bitterli, Natacha Bodenhausen, Yann Bonjour, Lucien Bovy, Tanja Boyandin, Eliane Breitenmoser, Christian Brönimann, Nathalie Brückner, Marcel Bucher, Stefan Bucher, Andreas Cadonau, Simone Cairoli, Elodie Calais, Bruno Campana, Catrina Canetta Collenberg, Davide Carrara, Cristian Cattaneo, Ester‐Camilla Cattaneo, Renzo Cattori, Silvana Cavagna, Luciano‐Grazia Cavallini, Elio Cavargna, Laura Cerri, Marlis Chanton, Camilla Chiesa, Elisabeth Clément, Morgane Clivaz‐Duc, Léonie Cocquio, Helio Correia, Cristina Corti, Stefano Corti, Fabien Dauphin, Annette Délétroz, Nicola Della Casa, Francesco Denova, Yannick Ducommun, Jacques Dugon, Monique Duplan, Lisa Ehrler, Bruno Enz, Philipp Fässler, Alain Favre, Urs Fellmann, Nadine Fischer, Serge Fischer, Johann‐Peter Flisch, Franklyn Foresti, Paola Frapolli, Simon Freiburghaus, Edie Freisinger, Peter Gamper, Agnes‐Julia Geissberger, Frères Girardin, Stephan Goppel, Fabiana Greco, Ueli Grossniklaus, Gabriela Grubenmann, Marc‐Henri Guex, Urs Hähni, Martina Haller, Gerhard Hardegger, Kyle Hartman, Anastase Hategekimana, Regula Hegglin, Matteus Heiter, Andreas Hellwig, Sandra‐John Hemsley, Chantal Herzog, Stephan Herzog, Ruedi Hess, Werner Hilber, Sarah‐Lea Hipp, Jolanda Hofmann, Mirjam Hofmann, Thomas Holdener, Mischa Hug, Erol Incesu, Sebastian Ineichen, David Iten, Regula‐Christoph Jakob, Peter Jann, Salomé‐David Jantz Bröckelmann, Markus Jocher, Simon Jöhr, Jasmin Joshi, Andreas Jud, Corinne Jud, Beatrice Jung, Daniel Jutzi, Walter Käch, Franziska‐Oli Kägi, Franziska Kaguembega‐Müller, Antonia Kaiser, Lukas Kammermann, Andreas Katz, Pirmin Kneubühler, Janique Koller, Eva Kollmann, Michèle Kraiem, Markus Künzler, Laura Kuonen, David Küttel, Romeo Ladina, Gabriella Lakatos, Anna Lazzarotto, Jean Lebedeff, Manuela Leonardi, Paola Leonardi, Simone Leoni, Eric Leuenberger, Corinne Lüthi, Sari Manaa, Simonetta Mauri, Harald Menzi, Vincenzo‐Corinne Meroni Held, Stephan Meyer, Stéphan Meylan, Matteo Minotti, Paola Molinari, Fabiola Monigatti, Vinciane Monod, Andrea Moroni‐Stampa, Jürg Moser, Res Moser, Alain Müller, Balz Müller, Laurence Müller, Nathalie Nevo, Stefan Odermatt, Lucia Oertle, Sandra Ott, Sébastien Oulevey, Ania Hans‐Peter Padrutt, Manuela Paltenghi, Nadia Paltenghi, Anna Parathazham, Nicolas Pavillard, Cesare Sonia Pedrazzini Giussani, Barbara Loris Pedroia, Alicia Perego, Paola Paolo Pieracci Cestari, Luisa Poggi, Mirko Ponti, Laurence Pot, Pierre‐Antoine Preti, Brice Prudat, Lina Rasheed, Dominique Raphael Reichenbach, Etienne Reichenbach, Beat Reidy, Ruedi Riniker, Chantal Ritter Cochand, Katharina Ritter, Julien Rondez, Fabien Roth, Adrian Rubi, Nicolas Ruch, Nicla‐Alex‐Mia‐Zoe‐Febe Rusca, Mirjam Rust, Erminia Salvi Knobloch, Alberto Sassella, Anke Schäfer, Beat Schär, Sabine Schärer, Patric Schatzmann, Belinda Schegg, Joël Scheidegger, Klaus Schläppi, Judith Schlegel, Marisa Schnüriger, Toni Schönbächler, Jürg Schönholzer, Coni Schweizer, Eugenio Scozzafava, Caroline Serafini, Tina Siegenthaler, Claudio Signer, Dustin Singer, Iris Solothurnmann, Rolf Sonderegger, Stefanie R. Spycher, Mirjam Stähli, Jean‐Pierre Stefanelli, Katja Stucki, Valentina Tanzi, Christina Thalmann, Sylvia Tiercy, Valentina Togni, Mathias Tönz, Paul Trachsel, Dino Troncatti, Pirmin‐Fredy Umbricht, Claude Valloton, Alexander van der Heijden, Liev van Moorsel, Sofia van Moorsel, Thea van Woerkom, Claude Varin, Manuela Villa‐Petraglio, Christophe Viltard, Florian Vogelsanger, Adrian von Niederhäusern, Barbara Walther, Jocelyn Widmer, Gianna Wullschleger, Thomas Würms, Thomas Wüthrich, Anita Zulliger, Renatus C. Zürcher, Thomas D. Bucheli, Marcel G. A. van der Heijden   +258 more
wiley   +1 more source

Practical Methodology for Developing Visions for Carbon‐Neutral Cities and Communities

Sustainable Development, EarlyView.
ABSTRACT Cities and communities play important roles in sustainable development and climate change mitigation. This study presents a novel framework for developing carbon‐neutral visions for cities and communities. We established five “principles,” investigated options encompassing four parameters (management, goal setting, actions, and quantification),
Kei Gomi, Makoto Ooba, Shogo Nakamura, Kohei Sakai, Satoshi Nagatomi   +4 more
wiley   +1 more source

Epidermal Growth Factor Upregulates Production of Supernumerary Hair Cells in Neonatal Rat Organ of Corti Explants

, 2000
peer reviewedThe organ of Corti is highly ordered, with a single row of inner hair cells and three rows of outer hair cells. The number of hair cells produced was thought to be limited by the time of their terminal mitosis (i.e.
Thiry, Marc, Van De Water, T. R., Lefebvre, P P, Malgrange, Brigitte, Thiry, M, Moonen, G, Malgrange, B, Lefèbvre, Philippe, Van De Water, T R, Moonen, Gustave   +9 more
core   +1 more source