Results 21 to 30 of about 17,899 (265)

Molecular profile of cochlear immunity in the resident cells of the organ of Corti [PDF]

open access: goldJournal of Neuroinflammation, 2014
BackgroundThe cochlea is the sensory organ of hearing. In the cochlea, the organ of Corti houses sensory cells that are susceptible to pathological insults. While the organ of Corti lacks immune cells, it does have the capacity for immune activity.
Qunfeng Cai   +7 more
openalex   +2 more sources

ILDR1 deficiency causes degeneration of cochlear outer hair cells and disrupts the structure of the organ of Corti: a mouse model for human DFNB42

open access: yesBiology Open, 2015
Immunoglobulin-like domain containing receptor 1 (ILDR1) is a poorly characterized gene that was first identified in lymphoma cells. Mutations in ILDR1 are responsible for DFNB42, but the pathogenesis of hearing loss caused by ILDR1 mutations remains to ...
Qing Sang   +9 more
doaj   +2 more sources

Identification of mouse cochlear progenitors that develop hair and supporting cells in the organ of Corti [PDF]

open access: goldNature Communications, 2017
The adult mammalian cochlear sensory epithelium houses two major types of cells, mechanosensory hair cells and underlying supporting cells, and lacks regenerative capacity.
Jin Xu   +5 more
openalex   +2 more sources

Organ of Corti: A Listening Device [PDF]

open access: greenLeonardo Music Journal, 2012
The author discusses a piece that recycles noise in the surrounding environment, inviting active listening and contemplation on the act of listening itself.
David Prior
openaire   +3 more sources

Expression of Neurog1 Instead of Atoh1 Can Partially Rescue Organ of Corti Cell Survival

open access: goldPLoS ONE, 2012
In the mammalian inner ear neurosensory cell fate depends on three closely related transcription factors, Atoh1 for hair cells and Neurog1 and Neurod1 for neurons.
Israt Jahan   +8 more
openalex   +3 more sources

Sox2 and FGF20 interact to regulate organ of Corti hair cell and supporting cell development in a spatially-graded manner.

open access: goldPLoS Genetics, 2019
The mouse organ of Corti, housed inside the cochlea, contains hair cells and supporting cells that transduce sound into electrical signals. These cells develop in two main steps: progenitor specification followed by differentiation.
Lu M Yang   +3 more
doaj   +3 more sources

Two-Dimensional Cochlear Micromechanics Measured In Vivo Demonstrate Radial Tuning within the Mouse Organ of Corti [PDF]

open access: bronzeJournal of Neuroscience, 2016
H. Y. Lee   +7 more
openalex   +2 more sources

Cochlea cell-specific marker expression upon in vitro Hes1 knockdown [PDF]

open access: yesBrazilian Journal of Medical and Biological Research, 2021
NOTCH pathway proteins, including the transcriptional factor HES1, play crucial roles in the development of the inner ear by means of the lateral inhibition mechanism, in which supporting cells have their phenotype preserved while they are prevented from
A.C. Batissoco   +9 more
doaj   +1 more source

Estradiol protects hair cells from cisplatin-induced ototoxicity via Nrf2 activation

open access: yesRedox Report, 2023
Cisplatin-induced ototoxicity is caused by reactive oxygen species. It has been recognized that estradiol (E2) regulates redox balance. However, little is known about the protective mechanisms of E2 against cisplatin-induced ototoxicity.
Masahiro Adachi   +5 more
doaj   +1 more source

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