Vascular Microphysiological System for Investigating Endothelial Barrier Function During Organ Preservation and Reperfusion. [PDF]
SmallEndothelial cell damage after cold preservation and reperfusion injury causes deterioration of the endothelial barrier and ultimately results in edema, leading to transplant failure.
Kim Y +14 more
europepmc +3 more sources
Organ preservation strategy: new therapeutic alternative in rectal cancer [PDF]
Journal of the Egyptian National Cancer Institute, 2023 Background The therapeutic modalities for nonmetastatic rectal cancer are presently undergoing major changes. The standard treatment is multidisciplinary, combining radiotherapy, chemotherapy, and surgery.
F. Safini +3 more
doaj +2 more sources
The European Larynx Organ Preservation Study [MK-3475-C44] [PDF]
Frontiers in OncologyThe European Larynx Organ Preservation Study (ELOS; NCT06137378) is a prospective, randomized, open-label, two-armed parallel group controlled, phase II multicenter larynx organ preservation (LOP) trial in locoregionally advanced (LA) stage III, IVA/B ...
Gunnar Wichmann +33 more
doaj +2 more sources
Evaluation of the presence of microorganisms in solid-organ preservation solution [PDF]
Brazilian Journal of Infectious Diseases, 2011 Objective: To assess the presence of microorganism contamination in the preservation solution for transplant organs (kidney/pancreas). Method: Between August 2007 and March 2008, 136 samples of preservation solution were studied prior to graft ...
André Marcelo Colvara Mattana +5 more
doaj +2 more sources
Hydrogen sulphide-induced hypometabolism in human-sized porcine kidneys. [PDF]
PLoS ONE, 2019 BACKGROUND:Since the start of organ transplantation, hypothermia-forced hypometabolism has been the cornerstone in organ preservation. Cold preservation showed to protect against ischemia, although post-transplant injury still occurs and further ...
Hanno Maassen +7 more
doaj +2 more sources
The Impact of Culturing the Organ Preservation Fluid on Solid Organ Transplantation: A Prospective Multicenter Cohort Study [PDF]
Open Forum Infectious Diseases, 2019 Background We analyzed the prevalence, etiology, and risk factors of culture-positive preservation fluid and their impact on the management of solid organ transplant recipients.
I. Oriol +37 more
semanticscholar +4 more sources
Development of a Novel Perfusable Solution for ex vivo Preservation: Towards Photosynthetic Oxygenation for Organ Transplantation [PDF]
Frontiers in Bioengineering and Biotechnology, 2021 Oxygen is the key molecule for aerobic metabolism, but no animal cells can produce it, creating an extreme dependency on external supply. In contrast, microalgae are photosynthetic microorganisms, therefore, they are able to produce oxygen as plant cells
Valentina Veloso-Giménez +10 more
semanticscholar +3 more sources
JAMA Netw OpenThis secondary analysis of a randomized clinical trial assesses organ preservation and survival outcomes for patients with rectal cancer according to a 3-tier clinical tumor response grading schema.
Hannah M Thompson +22 more
semanticscholar +2 more sources
PLoS ONE, 2019 Various methods have been devised to dissolve hydrogen gas in organ preservation solutions, including use of a hydrogen gas cylinder, electrolysis, or a hydrogen-generating agent.
Eiji Kobayashi, Motoaki Sano
doaj +2 more sources
Organ Preservation in Rectal Cancer: The Patients' Perspective
Frontiers in Oncology, 2019 Organ preservation after a clinical complete response to radiochemotherapy is currently one of the most discussed topics in the management of rectal cancer. However, the patients' perspective has only been poorly studied so far. In this multicenter study,
Cihan Gani +16 more
doaj +2 more sources