Results 11 to 20 of about 119,972 (311)

HTK-N: Modified Histidine-Tryptophan-Ketoglutarate Solution—A Promising New Tool in Solid Organ Preservation [PDF]

International Journal of Molecular Sciences, 2020
To ameliorate ischemia-induced graft injury, optimal organ preservation remains a critical hallmark event in solid organ transplantation. Although numerous preservation solutions are in use, they still have functional limitations.
Annika Mohr, Jens Brockmann, Felix Becker   +2 more
openalex   +2 more sources

Recent Advances in Organ Preservation Solutions and Methods for Using in Liver and Kidney Transplantation

مجله دانشکده پزشکی اصفهان, 2020
Background: The organ transplantation has been developed due to recent advances in transplantation surgery. The method of preservation and the type of preserving solution are determining factors in the outcome of the transplantations.
Zahra Jamadi, Parinaz Parhizgar, Ghasem Yazdanpanah, Tahereh Tayebi, Roghayeh Tarasi, Hassan Niknejad   +5 more
doaj   +2 more sources

Original and generic preservation solutions in organ transplantation. A new paradigm? [PDF]

Acta Cirúrgica Brasileira, 2020
Solid organ transplantation is a very complex process, in which the storage of the graft in a preservation solution is mandatory in order to extend ischemic times and contain further damage.
Joan Roselló-Catafau, Arnau Panisello-Roselló, Gianfranco Pasut, Miquel Navasa, Jacques Pirenne, René Adam   +5 more
doaj   +3 more sources

Evaluation of the presence of microorganisms in solid-organ preservation solution

Brazilian Journal of Infectious Diseases, 2011
OBJECTIVE: To assess the presence of microorganism contamination in the preservation solution for transplant organs (kidney/pancreas). Method: Between August 2007 and March 2008, 136 samples of preservation solution were studied prior to graft ...
André Marcelo Colvara Mattana, Alexandre Rodrigues Marra, Antônia Maria de Oliveira Machado, Gaspar de Jesus Lopes Filho, Alcides Augusto Salzedas Netto, Adriano Miziara Gonzalez   +5 more
doaj   +2 more sources

Tips for optimizing organ preservation solutions

Acta Biochimica Polonica, 2018
Organ injury during ischemia is one of the clinical problems of today's transplantation. It occurs during warm ischemia time (WIT) when the blood flow is cut off and during cold ischemia when a graft is chilled in situ until the circulation is restored to the recipient organism.
Aneta, Ostróżka-Cieślik, Barbara, Dolińska, Florian, Ryszka   +2 more
openaire   +4 more sources

Hyperbranched polyglycerol as a colloid in cold organ preservation solutions.

PLoS ONE, 2015
Hydroxyethyl starch (HES) is a common colloid in organ preservation solutions, such as in University of Wisconsin (UW) solution, for preventing graft interstitial edema and cell swelling during cold preservation of donor organs.
Sihai Gao, Qiunong Guan, Irina Chafeeva, Donald E Brooks, Christopher Y C Nguan, Jayachandran N Kizhakkedathu, Caigan Du   +6 more
doaj   +2 more sources

Current Trends in Organ Preservation Solutions for Pancreas Transplantation: A Single-Center Retrospective Study [PDF]

Transplant International, 2022
GRAPHICAL ABSTRACT Due to the high vulnerability of the pancreas to ischemia-reperfusion injury, choices regarding preservation solution markedly affect pancreas transplant success. A retrospective single-center analysis of 380 pancreas transplants (2000–
Joana Ferrer, Emma Folch‐Puy, Juan José Lozano, Pedro Ventura‐Aguiar, Gabriel Cárdenas, David Paredes, Ángeles García‐Criado, Josep Antoni Bombí, Rocío García-Pérez, M.Á. López-Boado, R. Rull, Enric Esmatjes, M.J. Ricart, Fritz Diekmann, Constantino Fondevila, Laureano Fernández‐Cruz, Josep Fuster, Juan Carlos García‐Valdecasas   +17 more
openalex   +2 more sources

Organ preservation using a photosynthetic solution [PDF]

Transplantation Research, 2012
Abstract Background Organs harvested from a body lapsing into circulatory deficit are exposed to low O2/high CO2, and reach a critical point where original functionality after transplantation is unlikely. The present study evaluates the effect of respiratory assistance using Chlorella photosynthesis on preservation of
Yamaoka, Ippei, Kikuchi, Takeshi, Arata, Tomohiro, Kobayashi, Eiji   +3 more
openaire   +3 more sources

Organ preservation: current limitations and optimization approaches

Frontiers in Medicine
Despite the annual rise in patients with end-stage diseases necessitating organ transplantation, the scarcity of high-quality grafts constrains the further development of transplantation.
Qiulin Ran, Jiayi Zhang, Jisheng Zhong, Ji Lin, Shuai Zhang, Guang Li, Bin You   +6 more
doaj   +2 more sources

A Novel Preservation Solution Containing Quercetin and Sucrose for Porcine Kidney Transplantation

Transplantation Direct, 2020
Background. In organ transplantation, the University of Wisconsin (UW) solution has been the gold standard for organ preservation. Quercetin (Que) has numerous antioxidant and anti-inflammatory activities, and sucrose (Suc) may be effective for cold ...
Mikako Gochi, MD, Fuminori Kato, PhD, Asuka Toriumi, DVM, Tomoko Kawagoe, Shuichi Yotsuya, DVM, MSc, Daisuke Ishii, MD, Masahide Otani, MD, Yuji Nishikawa, MD, PhD, Hiroyuki Furukawa, MD, PhD, Naoto Matsuno, MD, PhD   +9 more
doaj   +2 more sources