Results 31 to 40 of about 463,068 (88)

Hyperbranched Polyglycerol as a Colloid in Cold Organ Preservation Solutions

open access: yesPLOS ONE, 2015
Hydroxyethyl starch (HES) is a common colloid in organ preservation solutions, such as in University of Wisconsin (UW) solution, for preventing graft interstitial edema and cell swelling during cold preservation of donor organs. However, HES has undesirable characteristics, such as high viscosity, causing kidney injury and aggregation of erythrocytes ...
Jayachandran N. Kizhakkedathu   +6 more
openaire   +5 more sources

The effect of organ preservation solutions on kidney tubular and endothelial cells [PDF]

open access: yesTransplant International, 1998
Organ preservation solutions have primarily been tested in whole organ animal models. In the current study, we have examined the effect of commonly used organ preservation solutions on both kidney tubular and endothelial cells. Primary human endothelial and kidney tubular cells were incubated at 4 degrees C in the following solutions: 0.9% saline (NS),
Isao Nakanishi   +2 more
openaire   +3 more sources

A Novel Preservation Solution Containing Quercetin and Sucrose for Porcine Kidney Transplantation

open access: yesTransplantation Direct, 2020
Background. In organ transplantation, the University of Wisconsin (UW) solution has been the gold standard for organ preservation. Quercetin (Que) has numerous antioxidant and anti-inflammatory activities, and sucrose (Suc) may be effective for cold ...
Mikako Gochi   +9 more
semanticscholar   +1 more source

A pathophysiologic study of the kidney tubule to optimize organ preservation solutions [PDF]

open access: yesKidney International, 2004
Tissue damage at the time of organ transplantation has a negative impact on the subsequent success of the procedure, both in the immediate and longer term. Hypothermia is the principal element used to prolong organ viability ex vivo, but paradoxically also induces cellular edema through inhibition of energy-dependent adenosine triphosphatases (ATPases).
J. Peter A. Lodge   +10 more
openaire   +3 more sources

IGL‐1 as a preservation solution in intestinal transplantation: a multicenter experience

open access: yesTransplant International, 2020
Intestinal transplantation (ITx) is a life-saving procedure for complicated intestinal failure. It is still characterized by a high risk of infection and rejection(1).
Emilio Canovai   +11 more
semanticscholar   +1 more source

Preparation and testing of solutions for organ perfusion and preservation in transplantation

open access: yesVojnosanitetski pregled, 2008
Background/Aim. Histidine-tryptophan-ketoglutarate (HTK) solution is the most frequently used solution for the preservation of abdominal organs by leading transplant centers worldwide. The aim of the study was to investigate whether it is possible to prepare this kind of perfusion solution in the hospital pharmacy.
Mirjana Antunovic, Dragana Aleksic
openaire   +4 more sources

Strategies in Organ Preservation-A New Golden Age.

open access: yesTransplantation, 2020
I this issue of Transplantation, attention is focused on a perennial challenge, organ preservation and its associated ischemia-reperfusion injury (IRI).
P. Friend
semanticscholar   +1 more source

Glycocalyx as a Useful Marker of Endothelial Injury in Liver Transplantation: The Role of Preservation Solution.

open access: yesTransplantation, 2020
T reported investigations from Schiefer et al, on the role of glycocalyx (GC) in orthotopic liver transplantation, propose GC as a relevant injury marker to be used in this field.
Arnau Panisello-Roselló   +5 more
semanticscholar   +1 more source

A modified CZ-1 preserving solution for organ transplantation: comparative study with UW preserving solution

open access: yesChinese Medical Journal, 2008
The University of Wisconsin colloid based preserving solution (UW solution) is the most efficient preserving solution for multiorgan transplantation. Unfortunately, unavailability of delayed organ preserving solutions hindered further progression of cardinal organ transplantation in China.
Yu-li Li   +8 more
openaire   +3 more sources

The effect of organ preservation solutions on short‐term outcomes after liver transplantation: a single‐center retrospective study

open access: yesTransplant International, 2020
The effect of preservation solutions on outcomes has been subject of many debates but the relative benefits of the various solutions remain unclear. We retrospectively compared short‐term outcomes of 885 liver transplantations performed between 1/2000 ...
Jef Van den Eynde   +7 more
semanticscholar   +1 more source

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