A novel organ preservation solution with efficient clearance of red blood cells improves kidney transplantation in a canine model [PDF]
Cell & Bioscience, 2018 Organ preservation solutions are designed to minimize organ damage during transplantation. A novel preservation solution, WMO-II, was developed to have a low viscosity and to improve microvasculature perfusion for kidneys.
Sheng Wang +12 more
doaj +2 more sources
Nanotechnology-driven advancements in organ transplantation: Multifaceted strategies for organ preservation, ischemia reperfusion injury, immunomodulation and post-transplant monitoring [PDF]
Materials Today BioOrgan transplantation faces critical challenges, including donor shortages, suboptimal preservation, ischemia-reperfusion injury (IRI), and immune rejection.
Ziyin Chen +5 more
doaj +2 more sources
Development of a Novel Perfusable Solution for ex vivo Preservation: Towards Photosynthetic Oxygenation for Organ Transplantation [PDF]
Frontiers in Bioengineering and Biotechnology, 2021 Oxygen is the key molecule for aerobic metabolism, but no animal cells can produce it, creating an extreme dependency on external supply. In contrast, microalgae are photosynthetic microorganisms, therefore, they are able to produce oxygen as plant cells
Valentina Veloso-Giménez +14 more
doaj +2 more sources
PLoS ONE, 2019 Various methods have been devised to dissolve hydrogen gas in organ preservation solutions, including use of a hydrogen gas cylinder, electrolysis, or a hydrogen-generating agent.
Eiji Kobayashi, Motoaki Sano
doaj +2 more sources
Current Trends in Organ Preservation Solutions for Pancreas Transplantation: A Single-Center Retrospective Study. [PDF]
Transpl Int, 2022 Ferrer-Fàbrega J +17 more
europepmc +3 more sources
Novel vs clinical organ preservation solutions: improved cardiac mitochondrial protection. [PDF]
J Cardiothorac Surg, 2017 Ferng AS +5 more
europepmc +3 more sources
Improving the viability of tissue‐resident stem cells using an organ‐preservation solution [PDF]
FEBS Open Bio, 2019 Human clinical specimens are a valuable source of tissue‐resident stem cells, but such cells need to be collected immediately after tissue collection. To extend the timescale for collection from fresh human samples, we developed a new extracellular fluid
Takaya Suzuki +8 more
doaj +2 more sources
The novel compound PICCS improves cell viability during cold storage and reduces pulmonary ischemia-reperfusion injury in a rat model [PDF]
Scientific ReportsA simple method to achieve better organ preservation is the addition of compounds to the preservation solution, which effectively inhibits cold injury.
Yuhei Yokoyama +12 more
doaj +2 more sources
Organ Transplantation: Current Status, Challenges, and Future Prospects [PDF]
MedCommOrgan transplantation has progressed from a life‐saving surgical intervention to a multidisciplinary field integrating immunology, bioengineering, and data science.
Xinqiang Li, Ruidong Ding, Jinzhen Cai
doaj +2 more sources
Development of New Organ Preservation Solutions in Kyoto University
Yonsei Medical Journal, 2004 Although lung transplantation (LTx) has been established as a therapeutic approach for end-stage respiratory failure, several problems remain to be solved. In addition to the serious problem of donor shortage, primary graft failure, which is mostly caused by ischemia-reperfusion injury, a serious problem, and represents one of the most frequent causes ...
Fengshi, Chen +2 more
openaire +3 more sources