Results 201 to 210 of about 108,308 (280)

Turnip mosaic virus utilizes the lipid droplet biogenesis machinery to facilitate its propagation in plants

New Phytologist, EarlyView.
Potyvirus turnip mosaic virus induces neutral lipid accumulation and lipid droplet biogenesis in infected leaves for its own benefit. Summary Lipid droplets (LDs), which are dedicated to storing neutral lipids (NLs), are dynamic organelles involved in numerous other functions, including membrane remodeling during abiotic stress.
Léna Jambou, Nathalie Arvy, Marguerite Batsale, Luc Sofer, Sara Shakir, Marielle Cochet, Vincent Simon, Charlotte Quinteau, Thomas Scotti, Nathan M. Doner, Satinder K. Gidda, Robert T. Mullen, Sabine D'Andréa, Jean‐Luc Gallois, Denis Coulon, Claire Bréhélin, Sylvie German‐Retana   +16 more
wiley   +1 more source

Unfolding Plant Defence: Endoplasmic Reticulum Stress Signalling at the Plant‐Pathogen Interface

Plant Biotechnology Journal, EarlyView.
ABSTRACT The endoplasmic reticulum (ER) stress response, a conserved proteostasis network, has emerged as a central hub that reprograms plant immunity during pathogen attack. This review synthesises how plants harness ER‐stress signalling to mount multilayered defences and how pathogens have evolved counterstrategies to subvert these pathways.
Zhe Meng, Shuqin Zheng, Federica Brandizzi, Yiran Liu, Chunlei Li, Congcong Ai, Yujiao Wang, Jiadong Qi, Xiuguo Zhang   +8 more
wiley   +1 more source

Long‐Term Salt Exposure Reprograms the Nicotiana tabacum BY‐2 Suspension Proteome and Metabolome Toward Stabilization of the Core Metabolic Pathways, Protein Turnover Machinery Modifications, and Protective Metabolome Adjustments

Plant, Cell &Environment, EarlyView.
ABSTRACT In this study, we analyzed a unique Nicotiana tabacum BY‐2 line that was gradually adapted to and subsequently maintained in 190 mM NaCl for over 15 years. Years of continuous high salinity shaped a stable “new homeostasis” in BY‐2 suspension cells. Salt‐adapted cells were smaller and formed tighter clusters. Metabolomics revealed constitutive
Anita Rzadkiewicz, Łukasz Marczak, Aleksander Strugała, Maria Tomys, Ewelina Ratajczak, Tomasz Skrzypczak, Przemysław Wojtaszek, Anna Kasprowicz‐Maluśki, Agnieszka Szuba   +8 more
wiley   +1 more source

Natural Product Treatment for Metabolic Dysfunction-Associated Steatotic Liver Disease: Targeted Mitochondrial Quality Control. [PDF]

Drug Des Devel Ther
Liu J, Li F, Zeng Q, Hu W, Yang L, Luo S, Lv F, Li D, Deng Y.   +8 more
europepmc   +1 more source

Optimal timing to assess exercise‐induced oxidative stress: A systematic review and meta‐analysis

Experimental Physiology, EarlyView.
Abstract There is a lack of consensus on optimal timing to assess redox biomarkers post‐exercise, limiting methodological standardisation and linking oxidative stress to physiology. We determined optimal post‐exercise oxidative stress assessment times using three redox biomarkers: glutathione, F2‐isoprostanes and protein carbonyls.
Chrysovalantis Stachteas, Nikolaos Georgogiannis, George G. Nastos, Panagiotis N. Chatzinikolaou, Petros C. Dinas, Anastasios A. Theodorou, Vassilis Paschalis, Ioannis S. Vrabas, Antonios Kyparos, Athanasios Z. Jamurtas, Ioannis G. Fatouros, Michalis G. Nikolaidis, Nikos V. Margaritelis   +12 more
wiley   +1 more source

Spatial architecture of immunometabolism: Mitochondrial‑organelle interfaces in immune signaling (Review). [PDF]

Int J Mol Med
Wu Y, Yu H, Xia L, Yang L, Zhou Y, Yu Q.
europepmc   +1 more source

Mitophagy in skeletal muscle: Impact of ageing, exercise and disuse

Experimental Physiology, EarlyView.
Abstract Skeletal muscle plays an important role in whole‐body health, quality of life and regulation of metabolism. The maintenance of a healthy mitochondrial pool is imperative for the preservation of skeletal muscle quality and is mediated through mitochondrial quality control consisting of mitochondrial turnover mediated by a balance between ...
Anastasiya Kuznyetsova, David A. Hood
wiley   +1 more source

Heat treatment combined with hybrid exercises retraining mitigates cellular markers of protein turnover after hindlimb suspension in male mice: A pilot study

Experimental Physiology, EarlyView.
Abstract Recent evidence suggests that heat treatment (HT) and resistance training can limit skeletal muscle mass loss during immobilization. However, the effects of repeated HT sessions combined with hybrid exercises (EX), which promote both endurance and resistance responses, on muscle protein turnover following hindlimb unloading (HU) remain ...
Tom Normand‐Gravier, Robert Solsona, Christelle Bertrand‐Gaday, Margot Issertine, Florence Sabatier, Flavie Arnould, Sébastien Racinais, Fabio Borrani, Henri Bernardi, Anthony M. J. Sanchez   +9 more
wiley   +1 more source

Canonical and non‐canonical functions of proteins regulating mitochondrial dynamics in mammalian physiology

The Journal of Physiology, EarlyView.
Abstract figure legend Mitochondria are highly dynamic organelles that continuously remodel their architecture through coordinated cycles of fusion and fission. This review examines the four key GTPases that orchestrate mitochondrial dynamics in mammals: MFN1, MFN2, OPA1, and DRP1.
Rémi Chaney, Vincent Marcangeli, Krystel Desjardins, Shima Taherkhani, Gilles Gouspillou   +4 more
wiley   +1 more source

Lysosome-related organelles orchestrate guanine crystal formation in pigment cells. [PDF]

Proc Natl Acad Sci U S A
Gorelick-Ashkenazi A, Barzilay Y, Lerer-Goldshtein T, Olender T, Eyal Z, Glaser M, Broder Y, Mishol N, Deis R, Kedmi M, Gur D.   +10 more
europepmc   +1 more source