Results 261 to 270 of about 517,577 (347)
Effects of Centrifugal Force and Centrifugation Time on the Sedimentation of Plant Organelles
Jerry Nagahashi, Kathleen Hiraike
openalex +1 more source
RSPO2 and GDF9:BMP15 heterodimers—core components of oocyte‐secreted factors (OSFs)—coordinate to shape the molecular architecture of preantral granulosa cells via gene‐specific synergistic and antagonistic regulation, mediated through CTNNB1–SMAD2 signaling crosstalk.
Yingmei Wang+7 more
wiley +1 more source
A Prion‐Like Domain in EBV EBNA1 Promotes Phase Separation and Enables SRRM1 Splicing
This study discoveries that EBV EBNA1 behaves as a prion‐like protein, verified using cell‐based assays and the Saccharomyces cerevisiae Sup35p prion identification system. The prion‐like domain of EBNA1 drives liquid–liquid phase separation. EBNA1 interacts with the splicing factor SRSF1 to regulate the expression of the SRRM1 splicing isoforms ...
Xiaoyue Zhang+17 more
wiley +1 more source
Phase separation participates in the genetic regulation mechanism of hematopoietic stem cells: potential therapeutic methods. [PDF]
Tang X, Wang Y, Xu R.
europepmc +1 more source
AIE Luminogens for Bioimaging and Theranostics: From Organelles to Animals
J. Qian, J. Qian, B. Tang, B. Tang
semanticscholar +1 more source
Histone Demethylase UTX Suppresses Tumor Cell Proliferation by Regulating Stress Granules
These findings indicate that cytoplasmic UTX forms puncta and co‐localizes in stress granules (SGs) upon various stresses. UTX TPR‐domain‐dependently and demethylase‐activity‐independently destabilize SGs by binding G3BP1, the SG hub protein, to disrupt SG network, thus affects tumorigenesis.
Xikai Liu+17 more
wiley +1 more source
Mechanical stress activates PIEZO1 in vertebral growth plate chondrocytes, triggering ferroptosis through direct binding and inhibition of GPX4. This axis promotes lipid peroxidation and pathological ossification, accelerating spinal deformities. Clinical and genetic evidence (Piezo1‐cKO) confirms its role in scoliosis progression.
Fei Chen+14 more
wiley +1 more source
Rapid Miniprep of Intact Chloroplasts from <i>Arabidopsis thaliana</i> Leaves. [PDF]
Carranza-Correa BA+2 more
europepmc +1 more source