Results 41 to 50 of about 2,181,867 (291)
Anion channel sensitivity to cytosolic organic acids implicates a central role for oxaloacetate in integrating ion flux with metabolism in stomatal guard cells [PDF]
, 2011 Stomatal guard cells play a key role in gas exchange for photosynthesis and in minimizing transpirational water loss from plants by opening and closing the stomatal pore.
Yizhou Wang +5 more
core +1 more source
The Importance of Steroid Uptake and Intracrine Action in Endometrial and Ovarian Cancers
Frontiers in Pharmacology, 2017 Endometrial and ovarian cancers predominately affect women after menopause, and are more frequently observed in developed countries. These are considered to be hormone-dependent cancers, as steroid hormones, and estrogens in particular, have roles in ...
Tea Lanišnik Rižner +2 more
doaj +1 more source
Current Research in Food Science, 2022 The present study aimed to determine the effects of polysaccharides-riched Prunus mume fruit juice concentrate (PFC) on uric acid (UA) excretion and the gut microbiota in mice with chronic kidney disease (CKD).
Yan Huang +4 more
doaj +1 more source
The superfamily of organic anion transporting polypeptides
Biochimica et Biophysica Acta (BBA) - Biomembranes, 2003 Organic anion transporting polypeptides (Oatps/OATPs) form a growing gene superfamily and mediate transport of a wide spectrum of amphipathic organic solutes. Different Oatps/OATPs have partially overlapping and partially distinct substrate preferences for organic solutes such as bile salts, steroid conjugates, thyroid hormones, anionic oligopeptides ...
Hagenbuch, B., Meier, P. J.
openaire +2 more sources
Interactions of Human- and Rat-Organic Anion Transporters With Pravastatin and Cimetidine
Journal of Pharmacological Sciences, 2004 We have elucidated the interactions of human and rat organic anion transporters (hOATs and rOATs) with pravastatin and cimetidine. Pravastatin inhibited hOAT1/rOAT1, hOAT2/rOAT2, hOAT3/rOAT3, and hOAT4. The mode of inhibition was noncompetitive for hOAT1
Suparat Khamdang +8 more
doaj +1 more source
, 2019 Supplemental Data for Renal Secretion of Hydrochlorothiazide Involves Organic Anion Transporter 1/3, Organic Cation Transporter 2, and Multidrug and Toxin Extrusion Protein 2-
David Wagner (6491240)
core +1 more source
Choroid plexus transport: gene deletion studies
Fluids and Barriers of the CNS, 2011 This review examines the use of transporter knockout (KO) animals to evaluate transporter function at the choroid plexus (the blood-CSF barrier; BCSFB). Compared to the blood-brain barrier, there have been few such studies on choroid plexus (CP) function.
Keep Richard F, Smith David E
doaj +1 more source
Effects of organic anion transporter inhibitors on MA cytotoxicity.
, 2015 The organic anion transporter inhibitor probenecid (P) blocked MA-induced LDH release, whereas succinic acid, p-aminohippuric acid (PAH) and taurocholic acid were ineffective.
Ali Tunç Tuncel (757088) +6 more
core +1 more source
Characterization of a human renal organic anion transporter [PDF]
, 2000 The renal excretion of organic anions, including a variety of endogenous substances, xenobiotics and their metabolites, involves an organic anion transport system with multiple specificity. The well characterized
Reid, Glen +5 more
core +1 more source
FEBS Letters, EarlyView.Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise +5 more
wiley +1 more source