Involvement of Organic Anion Transporters in the Pharmacokinetics and Drug Interaction of Rosmarinic Acid [PDF]
Pharmaceutics, 2021 We investigated the involvement of drug transporters in the pharmacokinetics of rosmarinic acid in rats as well as the transporter-mediated drug interaction potential of rosmarinic acid in HEK293 cells overexpressing clinically important solute carrier ...
Yun Ju Kang +5 more
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Recent Advances on the Regulations of Organic Anion Transporters [PDF]
PharmaceuticsThe organic anion transporter (OAT) family of over 10 members within the solute carrier (SLC) superfamily of membrane proteins plays critical roles in facilitating the flux of negatively charged molecules in and out of cell membranes.
Zhou Yu, Guofeng You
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The Importance of Steroid Uptake and Intracrine Action in Endometrial and Ovarian Cancers [PDF]
Frontiers in Pharmacology, 2017 Endometrial and ovarian cancers predominately affect women after menopause, and are more frequently observed in developed countries. These are considered to be hormone-dependent cancers, as steroid hormones, and estrogens in particular, have roles in ...
Tea Lanišnik Rižner +2 more
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(−)-Epigallocatechin-3-gallate Inhibits Human and Rat Renal Organic Anion Transporters [PDF]
ACS Omega, 2021 Tatsuya Kawasaki +3 more
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Renal Organic Anion Transporters 1 and 3 In Vitro: Gone but Not Forgotten [PDF]
International Journal of Molecular Sciences, 2023 Pedro Pinto, Simone H Stahl
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Post-translational regulation of the major drug transporters in the families of organic anion transporters and organic anion–transporting polypeptides [PDF]
Journal of Biological Chemistry, 2020 Wooin Lee, Yuichi Sugiyama
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Organic anion transporters also mediate the drug–drug interaction between imipenem and cilastatin [PDF]
Asian Journal of Pharmaceutical Sciences, 2020 Xiao-Kui Huo, Changyuan Wang, Qiang Meng
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Uremic Toxins in Organ Crosstalk
Frontiers in Medicine, 2021 Many putative uremic toxins—like indoxyl sulfate, p-cresol sulfate, kynurenic acid, uric acid, and CMPF—are organic anions. Both inter-organ and inter-organismal communication are involved.
Jerome Lowenstein, Sanjay K. Nigam
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Uptake Transporters at the Blood–Brain Barrier and Their Role in Brain Drug Disposition
Pharmaceutics, 2023 Uptake drug transporters play a significant role in the pharmacokinetic of drugs within the brain, facilitating their entry into the central nervous system (CNS).
Md Masud Parvez +4 more
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Interactions of organophosphate flame retardants with human drug transporters
Ecotoxicology and Environmental Safety, 2023 Organophosphate flame retardants (OPFRs) are environmental pollutants of increasing interest, widely distributed in the environment and exerting possible deleterious effects towards the human health. The present study investigates in vitro their possible
Valentin Tastet +6 more
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