Results 101 to 110 of about 114,242,522 (291)

THE ROLE OF THE CANALICULAR MULTISPECIFIC ORGANIC ANION TRANSPORTER IN THE DISPOSAL OF ENDOBIOTICS AND XENOBIOTICS

, 1994
Bile is an important excretory route for the elimination of amphiphilic organic anions, and hepatocytes are the primary secretory units of bile formation.
JANSEN, PLM, ELFERINK, RPJO
core   +1 more source

Blueberry ellagic acid attenuates potassium oxonate-induced hyperuricemia and renal injury in mice

Journal of Functional Foods
To investigate the effect of blueberry ellagic acid (BEA) on hyperuricemia, a hyperuricemia model was established in mice by intraperitoneal injection of potassium oxonate (300 mg/kg).
Yuping Zhu, Pan Yang, Jiao Xie, Chunlin Zhang, Tingyuan Ren   +4 more
doaj   +1 more source

Digitally Printed Eco‐Friendly Electronic Devices

Advanced Functional Materials, EarlyView.
Fabrication of electronics using eco‐friendly materials through digital printing routes is a promising strategy for improving life cycle sustainability and reducing the environmental impacts of conventional manufacturing. This review highlights state‐of‐the‐art eco‐friendly materials, green ink formulations, various resource‐efficient digital printing ...
Nitheesh M. Nair, Mikel Rincón‐Iglesias, Cristian Mendes‐Felipe, Fatemeh Etehadi, Senentxu Lanceros‐Méndez, Gerardo Hernandez‐Sosa   +5 more
wiley   +1 more source

Material Coupling in Hybrid Neuromorphic Devices: From Fundamentals to System‐Level Applications

Advanced Functional Materials, EarlyView.
Hybrid neuromorphic devices utilize heterointerfaces between emerging semiconductors, where charge transfer and trapping, ion or defect modulation, and photogating are translated into synaptic functions. This paper discusses coupling strategies that tailor interfacial electronic and ionic properties in organic semiconductors, metal oxides, two ...
Minsu So, Sunwoo Jeong, Youngmin Han, Fabrizio Torricelli, Hocheon Yoo, Junhwan Choi   +5 more
wiley   +1 more source

Changes of drug pharmacokinetics mediated by downregulation of kidney organic cation transporters Mate1 and Oct2 in a rat model of hyperuricemia.

PLoS ONE, 2019
The effects of hyperuricemia on the expression of kidney drug transporters and on the pharmacokinetics of several substrate drugs were examined. We first established a rat model of hyperuricemia without marked symptoms of chronic kidney failure by 10-day
Kei Nishizawa, Noriaki Yoda, Fumi Morokado, Hisakazu Komori, Takeo Nakanishi, Ikumi Tamai   +5 more
doaj   +1 more source

Architected Bio‐Based Iontronic Skin With Dual‐Mode Pressure and Strain Sensing

Advanced Functional Materials, EarlyView.
Bio‐based acrylates in combination with an ionic liquid create 3D‐printed ionogels with compositionally tuneable mechanics and ionic conductivity. Gyroid architectures amplify low‐pressure sensitivity while preserving robust strain sensing, enabling dual‐mode detection of pressure and deformation.
Maksims Jurinovs, Madara Veseta, Fevzihan Basarir, Beatrise Silava, Eduards Bakis, Krisjanis Smits, Olesja Starkova, Jaana Vapaavuori, Sergejs Gaidukovs   +8 more
wiley   +1 more source

Cyclic AMP stimulates sorting of the canalicular organic anion transporter (Mrp2/cMoat) to the apical domain in hepatocyte couplets [PDF]

, 1998
The canalicular membrane of rat hepatocytes contains an ATP-dependent multispecific organic anion transporter, also named multidrug resistance protein 2, that is responsible for the biliary secretion of several amphiphilic organic anions.
Roelofsen, Han, Boyer, James L., Keppler, Dietrich, Soroka, Carol J.   +3 more
core   +4 more sources

Biodegradable Conductors for Implantable and Wearable Transient Bioelectronics

Advanced Functional Materials, EarlyView.
Biodegradable conductors are essential building blocks for transient bioelectronics, enabling temporary sensing, stimulation, and energy transfer while eliminating the need for device retrieval. This review summarizes biodegradable metals, conducting polymers, ionic conductors, and conductive composites, highlighting degradation mechanisms, material ...
Yicheng Zhu, Yijun Liu, Naoji Matsuhisa
wiley   +1 more source

Interactions of Human Organic Anion Transporters With Aristolochic Acids

, 2010
Aristolochic acids (AAs), contained in Chinese herbal preparations, have been considered to induce nephropathy. In order to elucidate the molecular mechanisms of AA-induced nephrotoxicity, we have elucidated the interaction of human organic anion ...
Ellappan Babu, Michio Takeda, Rie Noshiro-Kofuji, Naohiko Anzai, Masaaki Yoshida, Ritsuo Nishida, Hitoshi Endou, Shiro Ueda, Toshiyuki Fukutomi   +8 more
core   +1 more source

Anti‐Inflammatory and Neuroactive Effects of Polymer‐Coated Iron Oxide Nanoparticles Functionalized With Interleukin 4 for Spinal Cord Injury

Advanced Healthcare Materials, EarlyView.
Polymer‐coated IONPs functionalized with IL‐4 display respective neuroactive and anti‐inflammatory actions on neural progenitor cells and macrophages/microglia in vitro. When examined chronically in a rat experimental model of spinal cord injury, rGO scaffolds carrying these nanosystems adequately integrate into the lesion, significantly reduce ...
Julia Martínez‐Ramírez, Paloma Lozano‐Picazo, María de Lamo‐Atencia, Andrea Ferreras, Esther Benayas‐Martín, Elena Fernández‐López, Marina Sánchez‐Petidier, Verónica Barranco‐Maresca, Víctor Caz, Anne des Rieux, Juliana M. Rosa, María del Puerto Morales, María C. Serrano   +12 more
wiley   +1 more source