Results 271 to 280 of about 114,242,522 (291)

Modulation Of CNS Neurotransmitter Levels And Associated Behaviors In Organic Anion Transporter 1 (Slc22a6) And Organic Anion Transporter 3 (Slc22a8) Knockout Mice

2014
VCU Theses and ...
openaire   +1 more source

Interaction of oral antidiabetic drugs with hepatic uptake transporters: focus on organic anion transporting polypeptides and organic cation transporter 1.

Diabetes, 2008
The uptake of drugs into hepatocytes is a key determinant for hepatic metabolism, intrahepatic action, their subsequent systemic plasma concentrations, and extrahepatic actions. In vitro and in vivo studies indicate that many drugs used for treatment of cardiovascular diseases (e.g., oral antidiabetic drugs, statins) are taken up into hepatocytes by ...
Iouri, Bachmakov, Hartmut, Glaeser, Martin F, Fromm, Jörg, König   +3 more
openaire   +1 more source

OAT1, Organic Anion Transporter 1

2007
Yohannes Hagos, Gerhard Burckhardt
openaire   +1 more source

Regulation of Organic Anion Transporters: Role in Physiology, Pathophysiology, and Drug Elimination

Pharmacology & Therapeutics, 2021
Haoxun Wang, Guofeng You, Yunzhou Fan
exaly  

Characterization of Uremic Toxin Transport by Organic Anion Transporters in the Kidney

Kidney International, 2004
Hiroyuki Kusuhara, Akira Takadate, Tsuneo Deguchi   +2 more
exaly  

Major Role of Organic Anion Transporter 3 in the Transport of Indoxyl Sulfate in the Kidney

Kidney International, 2002
Tetsuya Terasaki, Sumio Ohtsuki, Hitomi Takanaga   +2 more
exaly  

The importance of charged amino acids in the human Organic Anion Transporter 1

The organic anion transporter 1 (OAT1) is key for the secretion of organic anions in renal proximal tubules. However, not much is currently known about structure-activity relationships or substrate-binding and translocation. In this study we investigated the role of conserved charged residues possibly important for substrate binding and turnover of the
Rizwan, Ahsan Naqi, Burckhardt, Gerhard, Burckhardt, Gerhard, Georg-August-Universität Göttingen, Hardeland, Rüdiger, Doenecke, Detlef   +5 more
openaire   +1 more source

The Multispecific Organic Anion Transporter (OAT) Family

Pflugers Archiv European Journal of Physiology, 2000
Seok Ho Cha, Hitoshi Endou, T Sekine
exaly  

The Organic Anion Transporter (OATP) Family

Drug Metabolism and Pharmacokinetics, 2004
Takehiro Suzuki, Sadayoshi Itō, Masayuki Tanemoto   +2 more
exaly  

Identification of Multispecific Organic Anion Transporter 2 Expressed Predominantly in the Liver

FEBS Letters, 1998
Yoshikatsu Kanai, Seok Ho Cha, Hitoshi Endou   +2 more
exaly