Results 251 to 260 of about 43,519 (302)

Human OAT1, OAT3, OAT4 and OATP1A2 Facilitate the Renal Accumulation of Ochratoxin A. [PDF]

Pharmaceutics
Mahadeo A, Tsang YP, Zheng AR, Arnzen S, Rodriguez AG, Warren MS, Gáborik Z, Kelly EJ.   +7 more
europepmc   +1 more source

Ecotoxicity of Nitrated Monoaromatic Hydrocarbons in Aquatic Systems: Emerging Risks from Atmospheric Deposition of Biomass Burning and Anthropogenic Aerosols. [PDF]

Toxics
Bakija Alempijević S, Strmečki S, Mihaljević I, Frka S, Dragojević J, Jakovljević I, Smital T.   +6 more
europepmc   +1 more source

Elucidating the role of ABC transporters in the placental efflux of (-)- Δ⁹-tetrahydrocannabinol (THC) using a cocktail of ABC transport inhibitors. [PDF]

Placenta
Balhara A, Chen X, Kumar AR, Wasickanin ME, Monson JW, Damicis JR, Kinsman HJ, Ieronimakis N, Unadkat JD.   +8 more
europepmc   +1 more source

Expression and Functional Evaluation of ABC and SLC Transporters in Human Choroid Plexus Papilloma (HIBCPP) Cells: A Human Blood-Cerebrospinal Fluid Barrier Model. [PDF]

Pharm Res
Kurosawa T, Ohtsuki S, Ishikawa H, Schroten H, Schwerk C, Kubo Y, Deguchi Y.   +6 more
europepmc   +1 more source

Mechanistic insights into atorvastatin-induced hepatotoxicity: molecular pathways, clinical relevance, and strategies for safer personalized therapy. [PDF]

Clin Exp Med
Abdel-Rasol MA, El-Sayed WM.
europepmc   +1 more source

Maternal organophosphate pesticide exposure in relation to birthweight: Modification by placenta transporter genotype. [PDF]

Placenta
Nguyen DQ, Hyman S, Medley E, Bozack AK, Kahn LG, Kannan K, Guitierrez A, Aleksunes LM, Rivera-Núñez Z, Cowell W.   +9 more
europepmc   +1 more source

Impaired Transport Activity of Human Organic Anion Transporters (OATs) and Organic Anion Transporting Polypeptides (OATPs) by Wnt Inhibitors [PDF]

Journal of Pharmaceutical Sciences, 2021
The Wnt/β-catenin signaling pathway is dysregulated in diseases and Wnt inhibitors like PRI-724 are in clinical development. This study evaluated the regulatory actions of PRI-724 and other Wnt inhibitors on the transport activity of human renal Organic anion transporters (OATs) and Organic anion transporting polypeptides (OATPs).
wenying Shu, Xiaofeng Bao, Ling Zhu
exaly   +3 more sources

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Organic Anion Transporters

2002
Organic anion transporters were first identified in intestine, liver, and kidney based on extensive studies of membrane transport phenomena mainly of xenobiotics. Recent advances in membrane transport studies with the use of molecular biological approaches have confirmed the participation of such carrier-mediated transport in these tissues and the ...
A, Tsuji, I, Tamai
openaire   +2 more sources

The Organic Anion Transporter (OATP) Family

Drug Metabolism and Pharmacokinetics, 2004
In the last decade, many organic anion transporters have been isolated, characterized their distribution and substrates. The recently identified organic anion transporter family OATP (organic anion transporting polypeptide)/LST (liver-specific transporter) family, transport bile acids, hormones as well as eicosanoids, various compounds (BSP, HMG-CoA ...
Tsuyoshi, Mikkaichi, Takehiro, Suzuki, Masayuki, Tanemoto, Sadayoshi, Ito, Takaaki, Abe   +4 more
openaire   +2 more sources