Results 71 to 80 of about 21,525 (288)

A Molecular Shielding Strategy to Develop Low Protein Binding, Renal Clearable Pan‐Cancer Near‐Infrared Probes

open access: yesAdvanced Functional Materials, EarlyView.
A molecular shielding strategy to convert “protein‐sticky” and “non‐tumor specific” clinical ICG dye, into a “low protein binding” and “tumor‐targeting” dye with prolonged blood circulation and renal clearance is described. These shielded ICGs demonstrate strong tumor accumulation and optimal tissue clearance, resulting in high tumor‐to‐background ...
Li Xiang   +9 more
wiley   +1 more source

Extremely Long Electron Lifetime in Spontaneously Passivated Polycrystalline Perovskite Layers via Illumination‐Assisted Trap Filling

open access: yesAdvanced Functional Materials, EarlyView.
ABSTRACT Perovskite solar cells (PSCs) are promising next‐generation photovoltaics. The high performance of PSCs is attributed to the long carrier lifetimes of perovskite photoabsorbers. However, the carrier lifetimes of polycrystalline perovskite layers, which serve as the photoabsorbers in practical PSCs, have remained limited to several tens of ...
Naoyuki Nishimura   +2 more
wiley   +1 more source

A Novel Human Organic Anion Transporter NPT4 Mediates the Transport of Ochratoxin A

open access: yesJournal of Pharmacological Sciences, 2011
.: In the present study, we investigated the transport of nephrotoxic mycotoxin ochratoxin A (OTxA) by a novel human organic anion transporter hNPT4 using the Xenopus oocyte expression system.
Promsuk Jutabha   +6 more
doaj   +1 more source

Altered Renal Expression of Relevant Clinical Drug Transporters in Different Models of Acute Uremia in Rats. Role of Urea Levels

open access: yesCellular Physiology and Biochemistry, 2015
Background/Aims: Organic anion transporter 1 (Oat1) and 3 (Oat3) are organic anion transporters that play critical roles in the body disposition of numerous clinically important drugs.
Anabel Brandoni, Adriana M. Torres
doaj   +1 more source

Advances in Sustainable and Wearable Textile Based Soft Robotics

open access: yesAdvanced Functional Materials, EarlyView.
This Review examines advances in wearable textile‐based soft robotics, focusing on sustainable materials, integrated sensing, and scalable actuation. It discusses manufacturing and system integration across healthcare, assistive robotics, prosthetics, and human–machine interfaces, and highlights key challenges in circular design, including life‐cycle ...
Zahir Abbas   +6 more
wiley   +1 more source

The altered renal and hepatic expression of solute carrier transporters (SLCs) in type 1 diabetic mice. [PDF]

open access: yesPLoS ONE, 2015
Diabetes mellitus is a chronic metabolic disorder that significantly affects human health and well-being. The Solute carrier transporters (SLCs), particularly the Organic anion/cation transporters (Oats/Octs/Octns), Organic anion transporting ...
Chenghao Xu   +6 more
doaj   +1 more source

Polymer‐Redox Interactions Enhance Ferro/Ferricyanide Thermogalvanic Cells

open access: yesAdvanced Functional Materials, EarlyView.
Polyelectrolyte could modify the hydration structure of the redox couple in solution and improve the output performance of thermogalvanic cells, providing new fundamental insight into how electrostatic interactions can be exploited to tailor thermoelectric properties.
Pedro Santos Candiotto de Oliveira   +6 more
wiley   +1 more source

The role of organic anion transporters in diagnosing liver diseases by magnetic resonance imaging [PDF]

open access: yes, 2014
The expression and transport functions of organic anion transporters are modified in liver diseases, and therefore the vascular clearances of endogenous and exogenous organic anions that are taken up by these transporters have been used to assess liver ...
Müllhaupt, Beat   +3 more
core   +1 more source

Effect of Statin Lipophilicity on the Proliferation of Hepatocellular Carcinoma Cells

open access: yesBiology
The HMG-CoA reductase inhibitors, statins, are drugs used globally for lowering the level of cholesterol in the blood. Different clinical studies of statins in cancer patients have indicated a decrease in cancer mortality, particularly in patients using ...
Goda Glebavičiūtė   +2 more
doaj   +1 more source

Role of Transporters in Central Nervous System Drug Delivery and Blood-Brain Barrier Protection: Relevance to Treatment of Stroke

open access: yesJournal of Central Nervous System Disease, 2017
Ischemic stroke is a leading cause of morbidity and mortality in the United States. The only approved pharmacologic treatment for ischemic stroke is thrombolysis via recombinant tissue plasminogen activator (r-tPA). A short therapeutic window and serious
Hrvoje Brzica   +3 more
doaj   +1 more source

Home - About - Disclaimer - Privacy