Results 91 to 100 of about 21,525 (288)
Regulation of organic anion transport in the liver.
The Yale journal of biology and medicine, 1997 In several liver diseases the biliary transport is disturbed, resulting in, for example, jaundice and cholestasis. Many of these symptoms can be attributed to altered regulation of hepatic transporters. Organic anion transport, mediated by the canalicular multispecific organic anion transporter (cmoat), has been extensively studied.
Roelofsen, H. +2 more
openaire +2 more sources
This project contains extended data for "Effect of late second to early third trimester of pregnancy on the activity of renal organic anion transporters (OAT1 and OAT3): A biomarker study" manuscript which includes: 1.
Aarzoo Thakur, Jashvant D. Unadkat
core +2 more sources
, 2018 The aim of this study was to assess the effects of Keishibukuryogan (K-06) and Shakuyakukanzoto (TJ-68), commercial herbal medicines, on the substrate uptake activities of renal organic anion transporters.
Ho-Sung Lee +4 more
core +1 more source
Distinguishing Molecular Properties of OAT, OATP, and MRP Drug Substrates by Machine Learning
PharmaceuticsThe movement of organic anionic drugs across cell membranes is partly governed by interactions with SLC and ABC transporters in the intestine, liver, kidney, blood–brain barrier, placenta, breast, and other tissues.
Anisha K. Nigam +3 more
doaj +1 more source
Organic anion transporters in remote sensing and organ crosstalk
Pharmacology & TherapeuticsThe organic anion transporters, OAT1 and OAT3, regulate the movement of drugs, toxins, and endogenous metabolites. In 2007, we proposed that OATs and other SLC22 transporters are involved in "remote sensing" and organ crosstalk. This is now known as the Remote Sensing and Signaling Theory (RSST).
Jeffry C, Granados, Sanjay K, Nigam
openaire +2 more sources
Synthesis of AgBiS2 and AgInS2 Based on Formation Energies in Sulfur‐Rich Reducing Flame
Advanced Functional Materials, EarlyView.High‐surface‐area AgInS2 and AgBiS2 nanoparticles were synthesized via enclosed flame spray pyrolysis by tuning flame conditions and formation energies to guide phase formation. Flame parameters were tuned to suppress oxides and enable pure sulfide phase growth.
Muhammad Ali Martuza +7 more
wiley +1 more source
, 2007 The human organic anion transporters OAT1, OAT2, OAT3, OAT4 and URAT1 belong to a family of poly-specific transporters mainly located in kidneys. Selected OATs occur also in liver, placenta, and brain. OATs interact with endogenous metabolic end products
Burckhardt, Gerhard, Rizwan, Ahsan N.
core +1 more source
Marine Drugs, 2017 This study examined the urinary excretion of tetrodotoxin (TTX) modeled in a porcine renal proximal tubule epithelial cell line, LLC-PK1. Time course profiles of TTX excretion and reabsorption across the cell monolayers at 37 °C showed that the amount of
Takuya Matsumoto +6 more
doaj +1 more source
Advanced Materials, EarlyView.Fluorene‐functionalized spiro‐phenothiazine (PTZ‐Fl) exhibits strong Li+ affinity and thermal stability, enabling a PCE of 25.75% in small‐area cells and 22.07% in 25 cm2 modules. Under ISOS‐L3 conditions, PTZ‐Flbased devices retain over 80% efficiency after 1000 hours, demonstrating superior stability and scalability compared to spiro‐OMeTAD for next ...
Javier Urieta‐Mora +17 more
wiley +1 more source
, 1999 BACKGROUND & AIMS: Liver regeneration in response to various forms of injury or surgical resection is a complex process resulting in restoration of the original liver mass and maintenance of liver-specific functions such as bile formation. However, liver
Gartung, C. +6 more
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