Results 101 to 110 of about 43,519 (302)

Regiorandom Polythiophenes for Fully Stretchable Electrochemical Transistors and Logic Circuits

Advanced Functional Materials, EarlyView.
Regiorandom (RRa) polythiophenes, once regarded as unsuitable for electronics, exhibit exceptional switching performance via volumetric electrochemical doping. Optimized RRa‐based organic electrochemical transistors (OECTs) achieve a high on/off ratio (≈104), stable operation under 200% strain, and enable fully stretchable logic gates, demonstrating ...
Dong Hyun Park, Min Su Kim, Kyu Yeon Kim, Jae Hyun Han, Moon Sung Kang, Kyung Gook Cho, Keun Hyung Lee   +6 more
wiley   +1 more source

Dysregulation of the mRNA Expression of Human Renal Drug Transporters by Proinflammatory Cytokines in Primary Human Proximal Tubular Epithelial Cells

Pharmaceutics
Proinflammatory cytokines, which are elevated during inflammation or infections, can affect drug pharmacokinetics (PK) due to the altered expression or activity of drug transporters and/or metabolizing enzymes.
Yik Pui Tsang, Tianran Hao, Qingcheng Mao, Edward J. Kelly, Jashvant D. Unadkat   +4 more
doaj   +1 more source

Polarization and Charge Transfer in the Hydration of Chloride Ions

, 2009
A theoretical study of the structural and electronic properties of the chloride ion and water molecules in the first hydration shell is presented.
Bader R. F. W., David M. Rogers, Dommert F., Hille B., Ninham B., Stein W. D., Thomas L. Beck, Zhen Zhao   +7 more
core   +1 more source

Strain‐Programmable Luminescent Adhesive Patch With Tartrazine‐Mediated Optical Skin Clearing for Photochemical Tissue Bonding

Advanced Functional Materials, EarlyView.
We propose a suture‐complementary approach that integrates optical skin clearing with a strain‐programmable luminescent adhesive patch. Hyaluronic acid promotes transdermal delivery of tartrazine to improve optical clearing and stabilizes its interaction with a photosensitizer. Optical clearing increases the penetration depth of visible light into skin,
Seong‐Jong Kim, Kyungjoo Jo, Kwanghyeon Park, Jun Hee Kim, Jong Hyeong Cho, Inhoo Choi, Sei Kwang Hahn   +6 more
wiley   +1 more source

Distinguishing Molecular Properties of OAT, OATP, and MRP Drug Substrates by Machine Learning

Pharmaceutics
The movement of organic anionic drugs across cell membranes is partly governed by interactions with SLC and ABC transporters in the intestine, liver, kidney, blood–brain barrier, placenta, breast, and other tissues.
Anisha K. Nigam, Jeremiah D. Momper, Anupam Anand Ojha, Sanjay K. Nigam   +3 more
doaj   +1 more source

Urinary Excretion of Tetrodotoxin Modeled in a Porcine Renal Proximal Tubule Epithelial Cell Line, LLC-PK1

Marine Drugs, 2017
This study examined the urinary excretion of tetrodotoxin (TTX) modeled in a porcine renal proximal tubule epithelial cell line, LLC-PK1. Time course profiles of TTX excretion and reabsorption across the cell monolayers at 37 °C showed that the amount of
Takuya Matsumoto, Yui Ishizaki, Keika Mochizuki, Mitsuru Aoyagi, Yoshiharu Mitoma, Shoichiro Ishizaki, Yuji Nagashima   +6 more
doaj   +1 more source

In Situ 3D Bioprinting: Impact of Cross‐Linking on the Adhesive Properties of Hydrogels

Advanced Functional Materials, EarlyView.
In situ 3D bioprinting enables the direct deposition of cell‐laden, adhesive biomaterials for on‐site tissue regeneration. This review provides a comprehensive overview of how cross‐linking influences the bioadhesive properties of hydrogels used in 3D bioprinting, highlighting cross‐linking triggers, bioadhesion mechanisms, polymer interpenetration ...
Odile Romero Fernandez, Mulazim Hussain Asim, Shumaila Arshad, Gergely Kali, Andreas Bernkop‐Schnürch   +4 more
wiley   +1 more source

Identification of novel cell-impermeant fluorescent substrates for testing the function and drug interaction of Organic Anion-Transporting Polypeptides, OATP1B1/1B3 and 2B1. [PDF]

, 2018
Organic Anion-Transporting Polypeptides are multispecific membrane proteins that regulate the passage of crucial endobiotics and drugs across pharmacological barriers. OATP1B1 and OATP1B3 have been described to play a major role in the hepatic uptake of
Bakos, Éva, Kucsma, Nóra, Német, Orsolya, Patik, Izabel, Szakács, Gergely, Szepesi, Áron, Székely, Virág, Várady, György, Özvegy-Laczka, Csilla   +8 more
core   +2 more sources

Understanding the Role of Superhydrophobicity and Superhydrophilicity in Salt‐Spray Corrosion of Nanosecond Pulsed Laser‐Textured AA2024 Alloy

Advanced Functional Materials, EarlyView.
Nanosecond pulse laser texturing yields superhydrophobic and superhydrophilic AA2024 surfaces. Salt‐spray tests show that periodic superhydrophobic patterns suppress pitting, whereas superhydrophilic textures enhance it, linking laser‐induced morphology, wettability, and oxide chemistry to corrosion resistance.
Lis Geraldine Zschach, Robert Baumann, Eric Pohl, Angelika Wrzesińska‐Lashkova, Marcelo Sallese, Ignacio Tabares, Herman Heffner, Yana Vaynzof, Andrés Fabián Lasagni   +8 more
wiley   +1 more source

Plasma membrane transport of thyroid hormones and its role in thyroid hormone metabolism and bioavailability [PDF]

, 2001
Although it was originally believed that thyroid hormones enter target cells by passive diffusion, it is now clear that cellular uptake is effected by carrier-mediated processes.
Docter, R. (Roel), Friesema, E.C.H. (Edith), Hennemann, G. (George), Jong, M. (Marion) de, Krenning, E.P. (Eric), Visser, T.J. (Theo)   +5 more
core   +3 more sources