Results 11 to 20 of about 5,589,379 (336)

Electrifying Organic Synthesis [PDF]

Angewandte Chemie International Edition, 2018
AbstractThe direct synthetic organic use of electricity is currently experiencing a renaissance. More synthetically oriented laboratories working in this area are exploiting both novel and more traditional concepts, paving the way to broader applications of this niche technology.
Anton Wiebe, Tile Gieshoff, Sabine Möhle, Eduardo Rodrigo, Michael Zirbes, Siegfried R. Waldvogel   +5 more
openaire   +3 more sources

Photobiocatalytic Strategies for Organic Synthesis.

Chemical Reviews, 2023
Biocatalysis has revolutionized chemical synthesis, providing sustainable methods for preparing various organic molecules. In enzyme-mediated organic synthesis, most reactions involve molecules operating from their ground states.
Megan A Emmanuel, Sophie G Bender, Catherine Bilodeau, J. M. Carceller, Jacob S. DeHovitz, H. Fu, Yi Liu, B. Nicholls, Ouyang Yao, C. Page, Tianzhang Qiao, Felix C Raps, D. Sorigué, Shang Z. Sun, Joshua Turek-Herman, Yuxuan Ye, Ariadna Rivas-Souchet, Jingzhe Cao, T. Hyster   +18 more
semanticscholar   +1 more source

Bicyclobutanes as unusual building blocks for complexity generation in organic synthesis

Communications Chemistry, 2023
Bicyclobutanes are among the most highly strained organic compounds and are intriguing building blocks in organic synthesis. This review provides an overview of the recent developments in bicyclobutane synthesis, their synthetic utility and their modes ...
Maxim Golfmann, Johannes C. L. Walker
semanticscholar   +1 more source

Microbiota-Derived Metabolite Trimethylamine N-Oxide Protects Mitochondrial Energy Metabolism and Cardiac Functionality in a Rat Model of Right Ventricle Heart Failure

Frontiers in Cell and Developmental Biology, 2021
Aim: Trimethylamine N-oxide (TMAO) is a gut microbiota-derived metabolite synthesized in host organisms from specific food constituents, such as choline, carnitine and betaine. During the last decade, elevated TMAO levels have been proposed as biomarkers
Melita Videja, Melita Videja, Reinis Vilskersts, Reinis Vilskersts, Stanislava Korzh, Helena Cirule, Eduards Sevostjanovs, Maija Dambrova, Maija Dambrova, Marina Makrecka-Kuka   +9 more
doaj   +1 more source

Single-Atom Catalysis in Organic Synthesis.

Angewandte Chemie, 2023
Single-atom catalysts hold the potential to significantly impact the chemical sector, pushing the boundaries of catalysis in new, uncharted directions.
Vitthal B. Saptal, V. Ruta, Mark A. Bajada, G. Vilé   +3 more
semanticscholar   +1 more source

Knockout of Tmlhe in mice is not associated with autism spectrum disorder phenotypes or motor dysfunction despite low carnitine levels

Molecular Autism, 2023
Deletion of exon 2 of the trimethyllysine hydroxylase epsilon (TMLHE) gene was identified in probands with autism spectrum disorder (ASD). TMLHE encodes the first enzyme in carnitine biosynthesis, N6-trimethyllysine dioxygenase (TMLD).
Edgars Liepinsh, Baiba Svalbe, Gundega Stelfa, Solveiga Grinberga, Liga Zvejniece, Helgi B. Schiöth, Maija Dambrova   +6 more
doaj   +1 more source

Detection of Anti-viral Drug Riamilovir and Herbicides in Aqueous Media by Using Pyrene-based Fluorescent Chemosensors

Chimica Techno Acta, 2021
Two ethyleneglycol esters of 1-pyrene carboxylic acid were studied as chemosensors for the fluorescence “turn-off” detection of two nitro-containing analytes, such as antiviral drug Riamilovir (Triazavirin ®) and herbicidal agent dinitro-ortho-cresol ...
I. S. Kovalev, L. K. Sadieva, O. S. Taniya, D. S. Kopchuk, G. V. Zyryanov, E. N. Ulomsky, V. L. Rusinov, O. N. Chupakhin   +7 more
doaj   +1 more source

Photochemical and Electrochemical Applications of Proton-Coupled Electron Transfer in Organic Synthesis

Chemical Reviews, 2021
We present here a review of the photochemical and electrochemical applications of multi-site proton-coupled electron transfer (MS-PCET) in organic synthesis.
Philip R. D. Murray, J. H. Cox, Nicolas D Chiappini, Casey B. Roos, Elizabeth A. McLoughlin, Benjamin G. Hejna, Suong T. T. Nguyen, H. Ripberger, J. M. Ganley, Elaine Tsui, N. Y. Shin, Brian Koronkiewicz, Guanqi Qiu, R. Knowles   +13 more
semanticscholar   +1 more source

3-(Adenosylthio)benzoic Acid Derivatives as SARS-CoV-2 Nsp14 Methyltransferase Inhibitors

Molecules, 2023
SARS-CoV-2 nsp14 guanine-N7-methyltransferase plays an important role in the viral RNA translation process by catalyzing the transfer of a methyl group from S-adenosyl-methionine (SAM) to viral mRNA cap.
Olga Bobileva, Raitis Bobrovs, Evelina Elva Sirma, Iveta Kanepe, Anna L. Bula, Liene Patetko, Anna Ramata-Stunda, Solveiga Grinberga, Aigars Jirgensons, Kristaps Jaudzems   +9 more
doaj   +1 more source

Bispyrenylalkane Chemosensor for the Naked-eye Detection of Nitro-explosives

Chimica Techno Acta, 2021
Pyrene-based compounds have a great potential as fluorescent chemosensors for various analytes including common nitro-explosives, such as 2,4,6-trinitrotoluene (TNT).
I. S. Kovalev, L. K. Sadieva, O. S. Taniya, V. M. Yurk, A. S. Minin, D. S. Kopchuk, G. V. Zyryanov, V. N. Charushin, O. N. Chupakhin   +8 more
doaj   +1 more source