Results 61 to 70 of about 5,589,379 (336)
Chimica Techno Acta, 2018 Two mutually complementary synthetic approaches towards 3- and 3,4-disubstituted 1-(2-pyridyl) isoquinolines were studied. The aryne-based method was successfully used for the obtaining of the corresponding the 3-cyano-1-(2-pyridyl)isoquinolines in one ...
I. L. Nikonov +10 more
doaj +1 more source
Isoxazolyl-Derived 1,4-Dihydroazolo[5,1-c][1,2,4]Triazines: Synthesis and Photochemical Properties
Molecules, 2023 New fluorescent dyes containing an assembled 1,4-dihydroazolo[5,1-c][1,2,4]triazine (DAT) core and an isoxazole ring were synthesized through a reaction between diazopyrazole or diazoimidazoles and isoxazolyl-derived enamines in mild conditions.
Elena V. Sadchikova +4 more
doaj +1 more source
Machine‐Assisted Organic Synthesis [PDF]
Angewandte Chemie International Edition, 2015 AbstractIn this Review we describe how the advent of machines is impacting on organic synthesis programs, with particular emphasis on the practical issues associated with the design of chemical reactors. In the rapidly changing, multivariant environment of the research laboratory, equipment needs to be modular to accommodate high and low temperatures ...
Ley, Steven V +4 more
openaire +2 more sources
Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10
FEBS Letters, EarlyView.Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang +8 more
wiley +1 more source
Frontiers in Endocrinology, 2019 Background: Insulin plays a pivotal role in the regulation of both carbohydrate and lipid intermediate turnover and metabolism. In the transition from a fasted to fed state, insulin action inhibits lipolysis in adipocytes, and acylcarnitine synthesis in ...
Elina Makarova +13 more
doaj +1 more source
New monomers for (bi)pyridine-containing polymers
Chimica Techno Acta, 2020 Convenient methods for the synthesis of three monomers based on functionalized (bi)pyridines with using “1,2,4-triaizine” methodology have been developed.
A. P. Krinochkin +9 more
doaj +1 more source
Styrylpyridinium Derivatives for Fluorescent Cell Imaging
Pharmaceuticals, 2023 A set of styrylpyridinium (SP) compounds was synthesised in order to study their spectroscopic and cell labelling properties. The compounds comprised different electron donating parts (julolidine, p-dimethylaminophenyl, p-methoxyphenyl, 3,4,5 ...
Reinis Putralis +16 more
doaj +1 more source
Recent advances in photoelectrochemical cells (PECs) for organic synthesis
Organic Chemistry Frontiers, 2020 The application of PECs in organic synthesis reactions and their reaction mechanisms are highlighted.
Yan-Chen Wu +2 more
semanticscholar +1 more source
Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer
FEBS Letters, EarlyView.Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani +4 more
wiley +1 more source
Keratin/Hydrotalcites Hybrid Sponges as Promising Adsorbents for Cationic and Anionic Dyes
Frontiers in Bioengineering and Biotechnology, 2020 In this work, keratin sponges were prepared by freeze-drying method and tested for adsorption of Azure A and Methyl Orange dyes. The obtained materials showed a porosity of 99.92% and a mean pore size dimension of about 91 μm. The use of oxidized sucrose
Tamara Posati +5 more
doaj +1 more source