Results 101 to 110 of about 6,880,727 (281)

Liver organoids: modelling complexity in homeostasis and disease

FEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

Balancing the Bottom-Line: How Abusive Supervision and Relative Deprivation Influence Career Regret — The Moderating Role of Organisational Support

Purpose — Drawing on conservation of resources theory, this study explores the effect of managers’ abusive supervision and bottom-line mentality on employee relative deprivation and career regret.
Dzandu, M.D., Yawson, M.T.A., Hanu, C., Mensah, P.   +3 more
core   +1 more source

Epigenetic reprogramming of lineage switching in cancer

FEBS Letters, EarlyView.
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı, Burcu Akman, Ezgi Bağırsakçı, Nese Atabey, Serap Erkek‐Ozhan   +4 more
wiley   +1 more source

Organisational cognisance: introducing a cognitive dimension to the concept of organisational alignment [PDF]

, 2011
Contemporary understandings of the concept of organisational alignment in the management and education literature are predominantly strategic and structural in nature.
Jeyaraj, Senthurini
core  

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

FEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source

Child Support Services Handbook

, 2013
application/pdfThe Kansas Child Support Services (CSS) program helps children receive the financial support necessary for their growth and development.
Kansas Child Support Services.
core  

From Organisation’s Affective Commitment to Employees’ Extra Role Behaviour: A Sequential Effect

Journal of Work and Organizational Psychology
The aim of this study is to examine the association between organisation’s affective commitment and employees’ organisational citizenship behaviour.
Joaquín García-Cruz, Ramón Valle-Cabrera   +1 more
doaj   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

FEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass, Dana Reichmann, Gábor Erdős   +2 more
wiley   +1 more source

Organisational support as a moderator between emotional exhaustion and turnover intentions

Acta Commercii
Orientation: The study of food industry workers experiencing emotional exhaustion (EE) and their views on organisational support (OS) becomes a crucial concept of turnover research.
Jeremy Mitonga-Monga, Masase E. Mageza-Mokhethi   +1 more
doaj   +1 more source

Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding

FEBS Letters, EarlyView.
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança, Eline L. Jansen, Jorine M. Eeftens   +2 more
wiley   +1 more source