Malformin A1–mediated cytotoxicity in ovarian cancer cells occurs through pyroptosis and autophagy
This study investigated the effects of the natural compound Malformin A1 (MA1) on the cytoskeleton that regulates cell proliferation and migration. Disruption of the cytoskeleton can impair these processes and promote cancer cell death. MA1 disrupted cytoskeletal organization, induced DNA damage, inflammation, activated autophagy, and pyroptosis ...
Nada Abdullah Hassan +11 more
wiley +1 more source
HISTELCON 2019 Organisers and Representatives of Supporting Organisations [PDF]
openaire +1 more source
Organisational Support, Interprofessional Collaboration and Patient Safety Perceptions Among Healthcare Professionals in Saudi Hospitals. [PDF]
Mostoles RJ, Alharbi A.
europepmc +1 more source
Exploring 'work-life balance' at appraisal and how this links with organisational support. [PDF]
Ferguson J +3 more
europepmc +1 more source
Ionomycin suppresses cancer cell growth by disrupting mitochondrial transcription
In this study, we identify a new function for the selective Ca2+ ionophore, ionomycin, as an inhibitor of mitochondrial transcription. Both total and nascent RNA analyses revealed that ionomycin treatment reduces the transcription of mitochondrial genes.
Lishen Wang +10 more
wiley +1 more source
Ensuring Board Commitment to Organisational Development (OD)
Want to ensure Board Commitment to OD? Do your homework, talk to peers, and be ready to answer tough questions.This practical guidance note explores how foundations can secure and sustain board commitment to providing organisational development (OD ...
Izabela Jurczik-Arnold
core +1 more source
Integrating Workplace Learning Into Healthcare Settings: A Mixed-Methods Study to Inform Curriculum Design, Resource Allocation and Organisational Support. [PDF]
Ho Y +5 more
europepmc +1 more source
ATZ‐1 promotes DNA replication efficiency to maintain normal meiotic function
Absence of ATZ‐1 interferes with meiotic DNA replication and cell cycle function via CHK‐1. This causes downstream defects associated with DNA damage and genomic integrity. Taken together, this study suggests that ATZ‐1 influences DNA replication efficiency and cell cycle function to maintain normal meiotic function.
Taylin E. Gourley +5 more
wiley +1 more source
Dealing with organisational change: Can emotional intelligence enhance organisational learning?
Organisational learning is a method of successfully dealing with continuous change. Emotional aspects of change, however, are not addressed in any detail.
Jordan, Peter
core
Perceived Organisational Support, Work Engagement and Disaster Literacy Among Critical Care Reserve Nurses: A Cross-Sectional Path Analysis. [PDF]
Shu C, Shu Z, Yu Z, Wang L, Hu S, Hu B.
europepmc +1 more source

