Results 51 to 60 of about 78,797 (204)

Chromosomes distribute randomly to, but not within, human neutrophil nuclear lobes

iScience, 2021
Summary: The proximity pattern and radial distribution of chromosome territories within spherical nuclei are random and non-random, respectively. Whether this distribution pattern is conserved in the partitioned or lobed nuclei of polymorphonuclear cells
Christine R. Keenan, Michael J. Mlodzianoski, Hannah D. Coughlan, Naiara G. Bediaga, Gaetano Naselli, Erin C. Lucas, Qike Wang, Carolyn A. de Graaf, Douglas J. Hilton, Leonard C. Harrison, Gordon K. Smyth, Kelly L. Rogers, Thomas Boudier, Rhys S. Allan, Timothy M. Johanson   +14 more
doaj   +1 more source

Universal Cell Embeddings: A Foundation Model for Cell Biology

bioRxiv
Developing a universal representation space for cells which encompasses the tremendous molecular diversity of cell types within the human body and more generally, across species, would be transformative for cell biology.
Yanay Rosen, Yusuf H. Roohani, Ayush Agrawal, Leon Samotorčan, S. Quake, J. Leskovec   +5 more
semanticscholar   +1 more source

The Role of Spastin in Axon Biology

Frontiers in Cell and Developmental Biology, 2022
Neurons are highly polarized cells with elaborate shapes that allow them to perform their function. In neurons, microtubule organization—length, density, and dynamics—are essential for the establishment of polarity, growth, and transport. A mounting body
A. C. Costa, M. Sousa
semanticscholar   +1 more source

Tracing the Biological Roots of Knowledge [PDF]

, 2006
The essay is a critical review of three possible approaches in the theory of knowledge while tracing the biological roots of knowledge: empiricist, rationalist and developmentalist approaches. Piaget's genetic epistemology, a developmentalist
Nagarjuna, G.
core  

Fission yeast Bgs1 glucan synthase participates in the control of growth polarity and membrane traffic

iScience
Summary: Rod-shaped fission yeast grows through cell wall expansion at poles and septum, synthesized by essential glucan synthases. Bgs1 synthesizes the linear β(1,3)glucan of primary septum at cytokinesis. Linear β(1,3)glucan is also present in the wall
Mariona Ramos, Rebeca Martín-García, M. Ángeles Curto, Laura Gómez-Delgado, M. Belén Moreno, Mamiko Sato, Elvira Portales, Masako Osumi, Sergio A. Rincón, Pilar Pérez, Juan C. Ribas, Juan C.G. Cortés   +11 more
doaj   +1 more source

Temporal Coordination of Collective Migration and Lumen Formation by Antagonism between Two Nuclear Receptors

iScience, 2020
Summary: During development, cells undergo multiple, distinct morphogenetic processes to form a tissue or organ, but how their temporal order and time interval are determined remain poorly understood.
Xianping Wang, Heng Wang, Lin Liu, Sheng Li, Gregory Emery, Jiong Chen   +5 more
doaj   +1 more source

DAB2IP suppresses invadopodia formation through destabilizing ALK by interacting with USP10 in breast cancer

iScience, 2023
Summary: Invadopodia, being actin-rich membrane protrusions, play a vital role in tumor cell invasion and metastasis. Our previous studies have revealed some functions of the DOC-2/DAB2 interacting protein (DAB2IP) as a tumor suppressor.
Qingwen Huang, Rui Zhang, Yun Xia, Jie Shen, Hongliang Dong, Xiaolan Li, Deding Tao, Daxing Xie, Liang Liu   +8 more
doaj   +1 more source

Proceedings ICPW'07: 2nd International Conference on the Pragmatic Web, 22-23 Oct. 2007, Tilburg: NL [PDF]

, 2007
Proceedings ICPW'07: 2nd International Conference on the Pragmatic Web, 22-23 Oct.

core  

Subjective Evolution of Consciousness in Modern Science and Vedāntic Philosophy: Particulate Concept to Quantum Mechanics in Modern Science and Śūnyavāda to Acintya-Bhedābheda-Tattva in Vedānta [PDF]

, 2019
How the universe came to be what it is now is a key philosophical question. The hypothesis that it came from nothing or śūnya (as proposed by Stephen Hawking, among others) proves to be dissembling, since the quantum vacuum can hardly be considered a ...
Ph D. Shanta, PhD
core  

Precise and timely delivery of proteins within cells continues to be an exciting area of cell biology

Molecular Biology of the Cell, 2013
To deliver the right amount of the right protein to the right place at the right time is a fundamental cell biology event underlying diverse cellular, physiological, and pathological processes.
W. Hong, A. Spang
semanticscholar   +1 more source