Results 41 to 50 of about 154,070 (226)

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

open access: yesFEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source

The relevance of transformational leadership in shaping employee attitudes towards organizational change [PDF]

open access: yesEkonomski Anali, 2014
The subject of the research presented in this paper is the role of the leadership of change agents in the implementation of organizational change. The focus of research is on the micro-aspect of change, specifically on the impact of changes in ...
Penava Suada, Šehić Dževad
doaj   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

Sustainability and Organizational Change

open access: yesAmfiteatru Economic, 2012
The relevant and, above all, remarkable feature of sustainability is due to its "duality": on the one hand, it is an indispensable element within the companies even if, on the other hand, it increases the costs of many activities and processes.
Catălina Sitnikov
doaj  

ORGANIZATIONAL CHANGE AND COMMUNICATION STRATEGIES

open access: yesErciyes İletişim Dergisi, 2015
Despite the popularity of planned change efforts, the failure rates of implementation are as high as 50 to 70 percent. While these efforts are affected by technical issues, the organizations’ approach to change, technological capabilities, leadership ...
Yusuf Yüksel
doaj   +1 more source

Through the professional’s eyes: transfers of care during pregnancy, childbirth and the postpartum period

open access: yesBMC Health Services Research, 2020
Background In the Netherlands, the obstetric and neonatal healthcare system consists of multiple healthcare organizations. Due to this system, transfers between healthcare professionals are inevitable.
Cherelle M. V. van Stenus   +3 more
doaj   +1 more source

Time after time – circadian clocks through the lens of oscillator theory

open access: yesFEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo   +2 more
wiley   +1 more source

Dimensions of organizational change

open access: yesManagement : Journal of Contemporary Management Issues, 2000
A basic characteristic of business operations in developed economic environments is their continuous search for responses to very rapid changes in their broader and closer environment.
Jure Kovač
doaj  

Organizational Change and Temporal Myopia

open access: yesAnnals of Business Administrative Science, 2015
Managers are required to eliminate resistance for making organizational changes. Previous studies have suggested that managers with sufficient power should be aware of the need for an organizational change and promote such changes. However, these factors
Hidenori SATO
doaj   +1 more source

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

open access: yesFEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka   +11 more
wiley   +1 more source

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