Results 41 to 50 of about 10,956 (235)

Non-Covalent Organocatalyzed Domino Reactions Involving Oxindoles: Recent Advances

Molecules, 2017
The ubiquitous presence of spirooxindole architectures with several functionalities and stereogenic centers in bioactive molecules has been appealing for the development of novel methodologies seeking their preparation in high yields and selectivities ...
Tecla Gasperi, Martina Miceli, Jean-Marc Campagne, Renata Marcia de Figueiredo   +3 more
doaj   +1 more source

The aza-Morita-Baylis-Hillman reaction of electronically and sterically deactivated substrates. [PDF]

, 2012
The aza-Morita–Baylis–Hillman (azaMBH) reaction has been studied for electronically and sterically deactivated Michael acceptors. It is found that electronically deactivated systems can be converted with electron-rich phosphanes and pyridines as ...
Abermil, Abermil, Aggarwal, Aggarwal, Aggarwal, Anstiss, Basavaiah, Basavaiah, Basavaiah, Boris Maryasin, Bryantsev, Buskens, Christoph Lindner, D'Elia, De Rycke, De Rycke, Declerck, Fisher, Garnier, Garnier, Gausepohl, Guan, Hammett, Hansch, Heinrich, Held, Held, Held, Hendrik Zipse, Heo, Hill, Hoops, Ito, Kelly, Kelly, Kobayashi, Lei, Lei, Lindner, Liu, Liu, Lutz, Mansilla, Masson, Matsui, Matsui, Matsui, McDougal, McDougal, Raheem, Raman Tandon, Robiette, Shi, Shi, Shi, Shi, Shi, Shi, Shi, Singh, Singh, Singh, Tang, Wei, Wei, Wei, Wei, Xu, Yinghao Liu, Yu, Yukawa, Zhao   +71 more
core   +1 more source

Manganese‐Catalyzed Enantioselective Dearomative Epoxidation of Naphthalenes with Aqueous Hydrogen Peroxide

Angewandte Chemie, EarlyView.
The enantioselective epoxidation of naphthalenes into their corresponding arene oxides with aqueous hydrogen peroxide is described. The reaction combines dearomatization with installation of chemically versatile functionality in an enantioselective manner.
Najoua Choukairi Afailal, Siu‐Chung Chan, Miquel Costas   +2 more
wiley   +2 more sources

Asymmetric additions to dienes catalysed by a dithiophosphoric acid. [PDF]

, 2011
Chiral Brønsted acids (proton donors) have been shown to facilitate a broad range of asymmetric chemical transformations under catalytic conditions without requiring additional toxic or expensive metals.
Hamilton, Gregory, Rauniyar, Vivek, Shapiro, Nathan, TOSTE, F. Dean, Wu, Jeffrey   +4 more
core   +2 more sources

Stereodivergent propargylic alkylation of enals via cooperative NHC and copper catalysis

Nature Communications, 2022
The ability to construct multiple stereocenters in a modular fashion is an important goal of synthetic organic chemistry. Here the authors present a method to construct oxindoles in four stereoisomers with high enantioselectivity and diastereoselectivity
Yu-Hua Wen, Zi-Jing Zhang, Shuai Li, Jin Song, Liu-Zhu Gong   +4 more
doaj   +1 more source

Development of an Organoautocatalyzed Double σ‐Bond C(sp2)‐N Transamination Metathesis Reaction

Angewandte Chemie, EarlyView.
Organoautocatalyzed transamination metathesis of cyclic tertiary amines is disclosed as a high‐yielding, scalable reaction that proceeds under mild, catalyst‐free conditions. It operates via a multi‐step domino reaction mechanism, where an in situ‐formed pyrrolidinium salt functions as a HBD organoautocatalyst.
Volker Klein, Florian Schuster, Jonas Amthor, Harald Maid, Prabhakar Bijalwan, Fahmi Himo, Stefano Santoro, Svetlana B. Tsogoeva   +7 more
wiley   +2 more sources

Crystallographic investigation into the self-assembly, guest binding, and flexibility of urea functionalised metal-organic frameworks [PDF]

, 2017
Introduction of hydrogen bond functionality into metal-organic frameworks can enhance guest binding and activation, but a combination of linker flexibility and interligand hydrogen bonding often results in the generation of unwanted structures where the ...
Forgan, Ross S., Marshall, Ross J., McGuire, Jake, Wilson, Claire   +3 more
core   +1 more source

Advances in the Asymmetric Total Synthesis of Natural Products Using Chiral Secondary Amine Catalyzed Reactions of α,β-Unsaturated Aldehydes

Molecules, 2019
Chirality is one of the most important attributes for its presence in a vast majority of bioactive natural products and pharmaceuticals. Asymmetric organocatalysis methods have emerged as a powerful methodology for the construction of highly ...
Zhonglei Wang
doaj   +1 more source

Advances in asymmetric organocatalysis over the last 10 years

Nature Communications, 2020
Organocatalysis has become a major pillar of (asymmetric) catalysis. Here, the authors discuss recent trends in organocatalytic activation modes for challenging stereoselective transformations and the emerging integration with other fields, such as ...
Shao-Hua Xiang, Bin Tan
doaj   +1 more source

Stereocontrol in Conformationally Stable C(sp2)─C(sp3) Atropisomers

Angewandte Chemie, EarlyView.
Building in our expertize in the synthesis of trans‐dihydrobenzofurans via organocatalyzed domino Michael/O‐cyclization between β‐naphthols and nitroalkenes, we developed an efficient strategy to access a new family of atropisomers bearing a conformationally stable C(sp2)─C(sp3) bond and two stereogenic centers through simple and highly ...
Antoine Domain, Guishun Bai, Juan‐Carlos Castillo, Hassane Moussa Abdraman, Stéphane Humbel, Michel Giorgi, Jean‐Valère Naubron, Sara Chentouf, Jean Rodriguez, Xiaoze Bao, Damien Bonne   +10 more
wiley   +2 more sources