Results 51 to 60 of about 12,256 (221)
Kinetics and mechanism of organocatalytic aza-Michael additions: direct observation of enamine intermediates. [PDF]
, 2012 The imidazoles 1a–g add to the CC-double bond of the iminium ion 2 with rate constants as predicted by the equation log k = sN(N + E). Unfavourable proton shifts from the imidazolium unit to the enamine fragment in the adduct 3 account for the failure of
Ahrendt +33 more
core +1 more source
Nature Communications, 2022 Nitriles have proven to be useful functional groups in pharmaceuticals and polymers, both as active moieties themselves or as easy precursors to further transformations, but synthesis of benzonitriles with axial chirality has often been difficult.
Ya Lv +5 more
doaj +1 more source
N-Triflylphosphorimidoyl Trichloride: A Versatile Reagent for the Synthesis of Strong Chiral Brønsted Acids [PDF]
, 2017 A series of strong Brønsted acids has been synthesized in high yields using N-triflylphosphorimidoyl trichloride as reagent.
Kaib, P., Lee, S., List, B.
core +2 more sources
Cluster Preface: Non-Covalent Interactions in Asymmetric Catalysis [PDF]
, 2016 The successful harnessing of non-covalent interactions to activate functional groups and control selectivity in chemical reactions is a relatively recent phenomenon in synthetic chemistry, but one that has delivered ground-breaking results, particularly ...
Phipps, RJ
core +2 more sources
Cooperative effects between arginine and glutamic acid in the amino acid catalyzed aldol reaction [PDF]
, 2017 Catalysis of the aldol reaction between cyclohexanone and 4-nitrobenzaldehyde by mixtures of L-Arg and of L-Glu in wet DMSO takes place with higher enantioselectivity (up to a seven-fold enhancement in the anti- aldol for the 1:1 mixture) than that ...
Moyano i Baldoire, Albert +1 more
core +1 more source
Molecules, 2021 In our studies, the organocatalytic 1,3-dipolar cycloaddition between 2-nitrobenzofurans or 2-nitrobenzothiophene and N-2,2,2-trifluoroethyl-substituted isatin imines has been developed.
Maciej Saktura +4 more
doaj +1 more source
Counterion effects in iminium-activated electrophilic aromatic substitutions of pyrroles. [PDF]
, 2011 Electrophilic substitution of pyrroles by a,b-unsaturated iminium ions is slow in acetonitrile when only weakly basic counterions are present. When the reactions are carried out in the presence of KCF3CO2, fast deprotonation of the intermediate r-adducts
Albert +33 more
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Chemistry – A European Journal, EarlyView.Why add another catalyst when the product itself holds the power to catalyze its own formation? Autocatalysis in synthetic chemistry enhances reaction efficiency and uncovers novel catalytic behavior across both closed‐shell and open‐shell systems, expanding reactivity and enabling innovative design strategies.
Jaspreet Kaur, Joshua P. Barham
wiley +1 more source
Chiral Diol-Based Organocatalysts in Enantioselective Reactions
Molecules, 2018 Organocatalysis has emerged as a powerful synthetic tool in organic chemistry in the last few decades. Among various classes of organocatalysis, chiral diol-based scaffolds, such as BINOLs, VANOLs, and tartaric acid derivatives, have been widely used to ...
Truong N. Nguyen +3 more
doaj +1 more source
Thioether-catalysed tandem synthesis of furans and cyclic ethers or lactones [PDF]
, 2017 Acyclic conjugated ynenediones tethered to an alcohol or carboxylic acid are converted into furanyl-substituted cyclic ethers or lactones in a single step by treatment with the tetrahydrothiophene.
Clark, J. Stephen, Klaus, Verena
core +1 more source