Results 51 to 60 of about 16,879 (311)

Crystallographic investigation into the self-assembly, guest binding, and flexibility of urea functionalised metal-organic frameworks [PDF]

, 2017
Introduction of hydrogen bond functionality into metal-organic frameworks can enhance guest binding and activation, but a combination of linker flexibility and interligand hydrogen bonding often results in the generation of unwanted structures where the ...
Forgan, Ross S., Marshall, Ross J., McGuire, Jake, Wilson, Claire   +3 more
core   +1 more source

Halogen, Chalcogen, Pnictogen, and Tetrel Bonding in Non-Covalent Organocatalysis: An Update.

Angewandte Chemie
The use of noncovalent interactions based on electrophilic halogen, chalcogen, pnictogen, or tetrel centers in organocatalysis has gained noticeable attention.
Dragana Radic Jovanovic, Meghana Poliyodath Mohanan, Stefan M. Huber   +2 more
semanticscholar   +1 more source

Total Synthesis of Feglymycin Using Umpolung Amide Synthesis

Angewandte Chemie, EarlyView.
A total synthesis of the antiviral feglymycin is described, leveraging enantioselective umpolung amide synthesis (UmAS). The strategic use of UmAS to prepare the aryl glycine‐rich tridecapeptide reduced hazardous amide coupling agents by 50%, and replaced asymmetric synthesis reliant on toxic transition metals by organocatalysis.
Preston C. Gourville, Jade A. Bing, Rashanique D. Quarels, Sergey V. Tsukanov, Kenneth E. Schwieter, Kazuyuki Tokumaru, Amanda B. Stephens, Dawn M. Makley, Bo Shen, Abigail N. Smith, Jeffrey N. Johnston   +10 more
wiley   +2 more sources

N-heterocyclic germylenes: structural characterisation of some heavy analogues of the ubiquitous N-heterocyclic carbenes [PDF]

, 2019
The X-ray crystal structures of three N-heterocyclic germylenes (NHGes) have been elucidated including the previously unknown 1,3-bis(2,6-dimethylphenyl)diazagermol-2-ylidene (1).
Dodds, Christopher A., Kennedy, Alan R., Spicer, Mark D.   +2 more
core   +2 more sources

Electrochemical Enantioselective Oxidation of Indoles via Chiral Phosphoric Acid Catalysis in Cooperation with H3PO4 in Aqueous Media

Angewandte Chemie, EarlyView.
A binary organic–inorganic acid cooperative catalytic system has been developed to achieve highly enantioselective electrochemical oxidative rearrangement of indoles. The use of electricity as an oxidant in this case showed several advantages including environmental benignity and improved enantiocontrol.
Xuefeng Tan, Zhijie Zhou, Minhua Shao, Jianwei Sun   +3 more
wiley   +2 more sources

Stereodivergent propargylic alkylation of enals via cooperative NHC and copper catalysis

Nature Communications, 2022
The ability to construct multiple stereocenters in a modular fashion is an important goal of synthetic organic chemistry. Here the authors present a method to construct oxindoles in four stereoisomers with high enantioselectivity and diastereoselectivity
Yu-Hua Wen, Zi-Jing Zhang, Shuai Li, Jin Song, Liu-Zhu Gong   +4 more
doaj   +1 more source

The aza-Morita-Baylis-Hillman reaction of electronically and sterically deactivated substrates. [PDF]

, 2012
The aza-Morita–Baylis–Hillman (azaMBH) reaction has been studied for electronically and sterically deactivated Michael acceptors. It is found that electronically deactivated systems can be converted with electron-rich phosphanes and pyridines as ...
Abermil, Abermil, Aggarwal, Aggarwal, Aggarwal, Anstiss, Basavaiah, Basavaiah, Basavaiah, Boris Maryasin, Bryantsev, Buskens, Christoph Lindner, D'Elia, De Rycke, De Rycke, Declerck, Fisher, Garnier, Garnier, Gausepohl, Guan, Hammett, Hansch, Heinrich, Held, Held, Held, Hendrik Zipse, Heo, Hill, Hoops, Ito, Kelly, Kelly, Kobayashi, Lei, Lei, Lindner, Liu, Liu, Lutz, Mansilla, Masson, Matsui, Matsui, Matsui, McDougal, McDougal, Raheem, Raman Tandon, Robiette, Shi, Shi, Shi, Shi, Shi, Shi, Shi, Singh, Singh, Singh, Tang, Wei, Wei, Wei, Wei, Xu, Yinghao Liu, Yu, Yukawa, Zhao   +71 more
core   +1 more source

Nitrogen‐Centered Organic Persistent Radicals Catalyze Redox‐Neutral C─C Bond Forming Reactions

Angewandte Chemie, EarlyView.
Kuhn verdazyls, discovered over 60 years ago, are shown as effective catalysts for the first time. Their tunable redox properties enable organocatalytic redox‐neutral C─H arylation and C─H trifluoromethylation reactions without light activation.
Shrouq Mujahed, Jaysan Janabel, Kundan Shaw, Roberta Cagliani, Tynchtyk Amatov   +4 more
wiley   +2 more sources

Asymmetric Organocatalysis: A Survival Guide to Medicinal Chemists

Molecules, 2022
Majority of drugs act by interacting with chiral counterparts, e.g., proteins, and we are, unfortunately, well-aware of how chirality can negatively impact the outcome of a therapeutic regime.
Efraim Reyes, Liher Prieto, Andrea Milelli   +2 more
doaj   +1 more source

Stereodivergent, Diels-Alder-initiated organocascades employing α,β-unsaturated acylammonium salts: scope, mechanism, and application. [PDF]

, 2017
Chiral α,β-unsaturated acylammonium salts are novel dienophiles enabling enantioselective Diels-Alder-lactonization (DAL) organocascades leading to cis- and trans-fused, bicyclic γ- and δ-lactones from readily prepared dienes, commodity acid chlorides ...
Abbasov, Mikail E, Hudson, Brandi M, Romo, Daniel, Tantillo, Dean J   +3 more
core   +2 more sources