Results 1 to 10 of about 72,000 (263)
MicroRNA-214-3p Delivered by Bone Marrow Mesenchymal Stem Cells-Secreted Exosomes Affects Oxidative Stress in Alzheimer’s Disease Rats by Targeting CD151 [PDF]
OrganogenesisObjective This study probed the effect of targeted regulation of CD151 by microRNA-214-3p (miR-214-3p) delivered by bone marrow mesenchymal stem cells-secreted exosomes (BMSCs-exo) on oxidative stress and apoptosis of neurons in Alzheimer’s disease (AD ...
Luzy Zhang
doaj +2 more sources
Cold Spring Harbor Perspectives in Medicine, 2017 The prostate is a male exocrine gland that secretes components of the seminal fluid. In men, prostate tumors are one of the most prevalent cancers. Studies on the development of the prostate have given a better understanding of the processes and genes that are important in the formation of this organ and have provided insights into the mechanisms of ...
Jeffrey C, Francis, Amanda, Swain
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Optimized Individualized Nursing Improves Recovery and Reduces Complications in ICU Patients with Severe Pneumonia [PDF]
OrganogenesisObjective This study evaluates the effectiveness of optimized individualized nursing interventions on clinical outcomes in intensive care unit (ICU) patients with severe pneumoniaMethods In this randomized controlled trial, 76 patients with severe ...
Linjuan Wu, Jingchuan Lin
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Correlation of MicroRNA-31 with Endometrial Receptivity in Patients with Repeated Implantation Failure of In Vitro Fertilization and Embryo Transfer [PDF]
OrganogenesisObjective This trial probed the correlation between miR-31 expression and endometrial receptivity (ER) in patients with repeated implantation failure (RIF) of in vitro fertilization and embryo transfer (IVF-ET).Methods A retrospective study of 80 ...
Yan Tan +3 more
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Image-based Modelling of Organogenesis [PDF]
arXiv, 2015 One of the major challenges in biology concerns the integration of data across length and time scales into a consistent framework: how do macroscopic properties and functionalities arise from the molecular regulatory networks - and how can they change as a result of mutations?
Erkan Ünal +2 more
arxiv +6 more sources
The Role of SUMO1 Modification of SOX9 in Cartilage Development Stimulated by Zinc Ions in Mice [PDF]
OrganogenesisZinc ions play a pivotal role in facilitating the development of cartilage in mice. Nevertheless, the precise underlying mechanism remains elusive. Our investigation was centered on elucidating the impact of zinc deficiency on cartilage maturation by ...
Na Xue +7 more
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Tetramethylpyrazine Confers Protection Against Oxidative Stress and NLRP3-Dependent Pyroptosis in Rats with Endometriosis [PDF]
OrganogenesisTetramethylpyrazine (TMP) has been confirmed to suppress inflammation in endometriosis (EMs). Herein, this study investigated whether and how TMP affected NLRP3 inflammasomes and oxidative stress in EMs. After establishment of an EMs rat model, rats were
Ke Xu +3 more
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Current Opinion in Cell Biology, 2021 Organoids are three-dimensional structures that self-organize from human pluripotent stem cells or primary tissue, potentially serving as a traceable and manipulatable platform to facilitate our understanding of organogenesis. Despite the ongoing advancement in generating organoids of diverse systems, biological applications of in vitro generated ...
Kentaro Iwasawa, Takanori Takebe
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Organogenesis, 2023 Hard-to-heal wounds can be detrimental to patients’ quality of life. Currently, there is scarcity of therapeutic alternatives to mainstay surgical treatment, which uses the principles of tissue debridement, temporary wound coverage, and subsequent tissue
Hadjipanayi Ektoras +5 more
doaj +1 more source
A single-cell transcriptome atlas profiles early organogenesis in human embryos
Nature Cell Biology, 2023 Xu et al. provide a single-cell transcriptomic atlas of 4–6 week human embryos, thereby profiling early human organogenesis. The early window of human embryogenesis is largely a black box for developmental biologists.
Yichi Xu +9 more
semanticscholar +1 more source