Optimization of TX-100/SDS-based decellularized vascular material using ultrasound and chemical treatment: evaluation of structure and biosafety [PDF]
OrganogenesisDecellularized blood vessels with low immunogenicity and excellent biocompatibility are promising for tissue engineering and clinical applications.
Hongguang Chen +6 more
doaj +2 more sources
A novel tissue-engineered stent graft combining decellularized scaffold and bioresorbable stent: a pilot feasibility study in a porcine model [PDF]
OrganogenesisEndovascular aneurysm repair (EVAR) is a widely accepted treatment for aortic pathologies owing to its minimally invasive nature. However, long-term complications, such as stent graft migration and infection, remain unresolved, primarily due to the ...
Tatsuya Shimogawara +6 more
doaj +2 more sources
Exosomal miR-29a-3p derived from bone marrow stromal cells suppresses malignant behavior of NSCLC by regulating DNMT3A/JAK2/STAT3 axis [PDF]
OrganogenesisMicroRNAs (miRNAs) can be transported to tumor cells through exosomes secreted by bone marrow mesenchymal stem cells (BMSC-Exos) and exert regulatory functions within cells.
Chao Su, Xiaoliang Han, Kang Zhang
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A single-cell transcriptome atlas profiles early organogenesis in human embryos
Nature Cell Biology, 2023 Xu et al. provide a single-cell transcriptomic atlas of 4–6 week human embryos, thereby profiling early human organogenesis. The early window of human embryogenesis is largely a black box for developmental biologists.
Yichi Xu +9 more
semanticscholar +1 more source
Cold Spring Harbor Perspectives in Medicine, 2017 The prostate is a male exocrine gland that secretes components of the seminal fluid. In men, prostate tumors are one of the most prevalent cancers. Studies on the development of the prostate have given a better understanding of the processes and genes that are important in the formation of this organ and have provided insights into the mechanisms of ...
Jeffrey C, Francis, Amanda, Swain
openaire +2 more sources
Cytokinins – regulators of de novo shoot organogenesis
Frontiers in Plant Science, 2023 Plants, unlike animals, possess a unique developmental plasticity, that allows them to adapt to changing environmental conditions. A fundamental aspect of this plasticity is their ability to undergo postembryonic de novo organogenesis.
Ján Šmeringai +2 more
semanticscholar +1 more source
Embryo model completes gastrulation to neurulation and organogenesis
Nature, 2022 Embryonic stem (ES) cells can undergo many aspects of mammalian embryogenesis in vitro1–5, but their developmental potential is substantially extended by interactions with extraembryonic stem cells, including trophoblast stem (TS) cells, extraembryonic ...
G. Amadei +14 more
semanticscholar +1 more source
Toxics, 2023 Persistent organic pollutants (POPs) are posing major environmental and health threats due to their stability, ubiquity, and bioaccumulation. Most of the numerous studies of these compounds deal with single chemicals, although real exposures always ...
Gustavo Guerrero-Limón +4 more
doaj +1 more source
Long-term in toto Imaging of Cellular Behavior during Nerve Injury and Regeneration
Bio-Protocol, 2023 Accidental wounding of the peripheral nervous system leads to acute neural dysfunction. Normally, chronic deficits are overcome because peripheral nerves naturally regenerate.
Weili Tian +2 more
doaj +1 more source
Integration of spatial and single-cell transcriptomic data elucidates mouse organogenesis
Nature Biotechnology, 2021 Molecular profiling of single cells has advanced our knowledge of the molecular basis of development. However, current approaches mostly rely on dissociating cells from tissues, thereby losing the crucial spatial context of regulatory processes. Here, we
T. Lohoff +19 more
semanticscholar +1 more source