Results 21 to 30 of about 72,062 (325)
Long-term in toto Imaging of Cellular Behavior during Nerve Injury and Regeneration
Bio-Protocol, 2023 Accidental wounding of the peripheral nervous system leads to acute neural dysfunction. Normally, chronic deficits are overcome because peripheral nerves naturally regenerate.
Weili Tian +2 more
doaj +1 more source
Tumor Necrosis Factor Alpha Signaling and Organogenesis
Frontiers in Cell and Developmental Biology, 2021 Tumor necrosis factor alpha (TNF-α) plays important roles in processes such as immunomodulation, fever, inflammatory response, inhibition of tumor formation, and inhibition of viral replication.
K. You, Hui Gu, Zhengwei Yuan, Xuewen Xu
semanticscholar +1 more source
Toxics, 2023 Persistent organic pollutants (POPs) are posing major environmental and health threats due to their stability, ubiquity, and bioaccumulation. Most of the numerous studies of these compounds deal with single chemicals, although real exposures always ...
Gustavo Guerrero-Limón +4 more
doaj +1 more source
Organogenesis: Cutting to the Chase [PDF]
Current Biology, 2004 Gonad morphogenesis in Caenorhabditis elegans requires two secreted proteases. Recent studies show that alterations of the extracellular matrix component fibulin-1 rescue gonadogenesis in the absence of these proteases. This finding is a critical step toward understanding the role of extracellular matrix in organogenesis.
Jean E. Schwarzbauer +2 more
openaire +3 more sources
The single cell transcriptional landscape of mammalian organogenesis
Nature, 2019 Mammalian organogenesis is a remarkable process. Within a short timeframe, the cells of the three germ layers transform into an embryo that includes most of the major internal and external organs. Here we investigate the transcriptional dynamics of mouse
Junyue Cao +11 more
semanticscholar +1 more source
Cytokinin Signaling and De Novo Shoot Organogenesis
Genes, 2021 The ability to restore or replace injured tissues can be undoubtedly named among the most spectacular achievements of plant organisms. One of such regeneration pathways is organogenesis, the formation of individual organs from nonmeristematic tissue ...
K. Hnatuszko-Konka +3 more
semanticscholar +1 more source
Organogenesis, 2023 Based on successes in preclinical animal transplant models, adoptive cell therapy (ACT) with regulatory T cells (Tregs) is a promising modality to induce allograft tolerance or reduce the use of immunosuppressive drugs to prevent rejection.
Kassandra J. Baron, Hēth R. Turnquist
doaj +1 more source
, 2010 Developmental lung biology is a field that has the potential for significant human impact: lung disease at the extremes of age continues to cause major morbidity and mortality worldwide. Understanding how the lung develops holds the promise that investigators can use this knowledge to aid lung repair and regeneration. In the decade since the "molecular
Daniela Riccardi +13 more
openaire +3 more sources
Hepatology Communications, 2022 Liver cancer is an aggressive cancer associated with a poor prognosis. Development of therapeutic strategies for liver cancer requires fundamental research using suitable experimental models. Recent progress in direct reprogramming technology has enabled
Takeshi Goya +6 more
doaj +1 more source
Nature Communications, 2020 Visceral organs, such as the lungs, stomach and liver, are derived from the fetal foregut through a series of inductive interactions between the definitive endoderm (DE) and the surrounding splanchnic mesoderm (SM).
Lu Han +15 more
semanticscholar +1 more source