Results 31 to 40 of about 72,062 (325)
Arthritis Research & Therapy, 2022 Background Osteoarthritis is a degenerative disease of the knee that affects 250 million people worldwide. Due to the rising incidence of knee replacement and revision surgery, there is a need for a nonsurgical treatment to reduce pain and improve ...
Kelly A. Kimmerling +3 more
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Auxin-Regulated Lateral Root Organogenesis.
Cold Spring Harbor Perspectives in Biology, 2021 Plant fitness is largely dependent on the root, the underground organ, which, besides its anchoring function, supplies the plant body with water and all nutrients necessary for growth and development.
N. Cavallari +2 more
semanticscholar +1 more source
The Effect of Coculture with Nonparenchymal Cells on Porcine Hepatocyte Function
Cell Transplantation, 2001 Porcine hepatocytes are currently being investigated as a therapy for patients suffering from acute liver failure. Incorporating hepatocytes in an extracorporeal device that would stabilize a patient until transplantation or recovery could dramatically ...
Paul G. Gregory +3 more
doaj +1 more source
Adaptable haemodynamic endothelial cells for organogenesis and tumorigenesis
Nature, 2020 Endothelial cells adopt tissue-specific characteristics to instruct organ development and regeneration 1 , 2 . This adaptability is lost in cultured adult endothelial cells, which do not vascularize tissues in an organotypic manner.
Brisa Palikuqi +28 more
semanticscholar +1 more source
In Vitro Characterization of Porcine Hepatocyte Function
Cell Transplantation, 2000 The clinical consequences of acute liver failure are associated with high mortality. Intensive medical intervention is required to treat the symptoms of liver failure, including coagulopathy, metabolic instability, and encephalopathy. Providing temporary
Paul G. Gregory +3 more
doaj +1 more source
Inexhaustible hair-cell regeneration in young and aged zebrafish
Biology Open, 2015 Animals have evolved two general strategies to counter injury and maintain physiological function. The most prevalent is protection by isolating vital organs into body cavities.
Filipe Pinto-Teixeira +6 more
doaj +1 more source
Organogenesis, 2023 Prostate cancer (PCa) poses a serious burden to men. Interferon-β (IFN-β) is implicated in cancer cell growth. This study hence explored the regulation of IFN-β-modified human umbilical cord mesenchymal stem cell-derived exosomes (hUCMSC-Exos) in PCa ...
Haichao Yuan +3 more
doaj +1 more source
Organogenesis of the exocrine gland
Developmental Biology, 2004 Morphogenesis of exocrine glands is a complex stepwise process of epithelial ingrowth, ductal elongation, ductal branching, and alveolar or acinar differentiation. Emerging from an increasing number of mouse gene knockout, dominant-negative, and antisense models is the identification of a remarkable collection of cell adhesion molecules, growth factors,
Jiahu Wang, Gordon W. Laurie
openaire +3 more sources
Sonic Hedgehog Signaling in Organogenesis, Tumors, and Tumor Microenvironments
International Journal of Molecular Sciences, 2020 During mammalian embryonic development, primary cilia transduce and regulate several signaling pathways. Among the various pathways, Sonic hedgehog (SHH) is one of the most significant. SHH signaling remains quiescent in adult mammalian tissues. However,
K. Jeng, Chiung-Fang Chang, Shuru Lin
semanticscholar +1 more source
The Role of Gasdermin-D-Mediated Pyroptosis in Organ Injury and Its Therapeutic Implications
Organogenesis, 2023 Gasdermin-D (GSDMD) belongs to the Gasdermin family (GSDM), which are pore-forming effector proteins that facilitate inflammatory cell death, also known as pyroptosis.
Joud Mulla +2 more
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