Results 31 to 40 of about 136,612 (370)

Cell Therapy Approaches for Articular Cartilage Regeneration

Organogenesis, 2023
Articular cartilage is a common cartilage type found in a multitude of joints throughout the human body. However, cartilage is limited in its regenerative capacity.
Meagan J. Makarczyk
doaj   +1 more source

TEAD and YAP regulate the enhancer network of human embryonic pancreatic progenitors. [PDF]

, 2015
The genomic regulatory programmes that underlie human organogenesis are poorly understood. Pancreas development, in particular, has pivotal implications for pancreatic regeneration, cancer and diabetes.
A Kapoor, A Krapp, A Rada-Iglesias, A Sawada, A-C Binot, AF Hezel, AJ Saldanha, B Zhao, B Zhao, C Cortijo, C Haumaitre, C Trapnell, CHH Cho, CY McLean, DA Stoffers, DW Huang, E Kroon, E Rodríguez-Seguel, EF Chiang, F Argenton, F Esni, F Supek, FC Lynn, FC Pan, H Fang, H Fang, H Lango Allen, I Morán, I Rooman, J Bessa, J van Arensbergen, JM Oliver-Krasinski, K Kawakami, K Piper, K Piper, K Skouloudaki, KJ Gaulton, KM Petzold, KS Zaret, L Elghazi, L Pasquali, M Borowiak, M Carrasco, M Gannon, MA Maestro, MC Whitlock, MF Offield, MJL de Hoon, MN Weedon, MP Creyghton, N Bardeesy, N Gao, NM George, P Jacquemin, PA Seymour, R O’Rahilly, R Xie, RE Jennings, RF Luco, S Gupta, S Heinz, S Xuan, T Derrien, T Jowett, W Zhang, WA Whyte, Y Fujitani, Y Liu-Chittenden   +67 more
core   +2 more sources

The Effect of Coculture with Nonparenchymal Cells on Porcine Hepatocyte Function

Cell Transplantation, 2001
Porcine hepatocytes are currently being investigated as a therapy for patients suffering from acute liver failure. Incorporating hepatocytes in an extracorporeal device that would stabilize a patient until transplantation or recovery could dramatically ...
Paul G. Gregory, Christopher K. Connolly, Bryan E. Gillis, Susan J. Sullivan   +3 more
doaj   +1 more source

Inexhaustible hair-cell regeneration in young and aged zebrafish

Biology Open, 2015
Animals have evolved two general strategies to counter injury and maintain physiological function. The most prevalent is protection by isolating vital organs into body cavities.
Filipe Pinto-Teixeira, Oriol Viader-Llargués, Elen Torres-Mejía, Melissa Turan, Estela González-Gualda, Laura Pola-Morell, Hernán López-Schier   +6 more
doaj   +1 more source

Expression Levels of WNT Signaling Pathway Genes During Early Tooth Development

Organogenesis, 2023
It is known to all that Wnt signaling pathway plays an important role in the early development of tooth. Our previous research found that Wnt signaling pathway played crucial roles in dental development, and mutations in antagonist of Wnt signaling ...
Yuhan Song, Fujie Song, Xuan Xiao, Zhifeng Song, Shangfeng Liu   +4 more
doaj   +1 more source

Cotyledon organogenesis [PDF]

Journal of Experimental Botany, 2008
The cotyledon represents one of the bases of classification within the plant kingdom, providing the name-giving difference between dicotyledonous and monocotyledonous plants. It is also a fundamental organ and there have been many reports of cotyledon mutants in many species. The use of these mutants where they have arisen in Arabidopsis has allowed us
openaire   +2 more sources

Single cell transcriptomics identifies a signaling network coordinating endoderm and mesoderm diversification during foregut organogenesis

Nature Communications, 2020
Visceral organs, such as the lungs, stomach and liver, are derived from the fetal foregut through a series of inductive interactions between the definitive endoderm (DE) and the surrounding splanchnic mesoderm (SM).
Lu Han, P. Chaturvedi, Keishi Kishimoto, H. Koike, Talia Nasr, K. Iwasawa, Kirsten B. Giesbrecht, Phillip C. Witcher, Alexandra K. Eicher, Lauren E. Haines, Yarim Lee, J. Shannon, M. Morimoto, James M. Wells, T. Takebe, A. Zorn   +15 more
semanticscholar   +1 more source

GOLVEN peptide signalling through RGI receptors and MPK6 restricts asymmetric cell division during lateral root initiation [PDF]

, 2020
During lateral root initiation, lateral root founder cells undergo asymmetric cell divisions that generate daughter cells with different sizes and fates, a prerequisite for correct primordium organogenesis.
Alves Neubus Claus, Lucas, Beeckman, Tom, De Gernier, dr. Hugues, Drozdzecki, Andrzej, Fernandez Salina, Ana, Hoogewijs, Kurt, Jourquin, Joris, Madder, Annemieke, Maruta, Takanori, Morales, Stefania, Nimchuk, Zachary L., Opdenacker, Davy, Parizot, Boris, Peterson, Brenda, Russinova, Eugenia, Vangheluwe, Nick, Vannecke, Willem, Xu, Ke, Yu, Qiaozhi   +18 more
core   +1 more source

Cell Aggregation Culture Induces Functional Differentiation of Induced Hepatocyte-like Cells through Activation of Hippo Signaling

Cell Reports, 2018
Summary: Recent progress in direct lineage reprogramming has enabled the generation of induced hepatocyte-like (iHep) cells and revealed their potential as an alternative to hepatocytes for medical applications.
Junpei Yamamoto, Miyako Udono, Shizuka Miura, Sayaka Sekiya, Atsushi Suzuki   +4 more
doaj   +1 more source

Adaptable haemodynamic endothelial cells for organogenesis and tumorigenesis

Nature, 2020
Endothelial cells adopt tissue-specific characteristics to instruct organ development and regeneration 1 , 2 . This adaptability is lost in cultured adult endothelial cells, which do not vascularize tissues in an organotypic manner.
Brisa Palikuqi, Duc-Huy T. Nguyen, Ge Li, Ryan Schreiner, A. Pellegata, Y. Liu, D. Redmond, F. Geng, Yang Lin, J. Gómez-Salinero, Masataka Yokoyama, P. Zumbo, Tuo Zhang, Balvir Kunar, Mavee Witherspoon, Teng Han, A. Tedeschi, F. Scottoni, S. Lipkin, L. Dow, O. Elemento, J. Xiang, K. Shido, J. Spence, Qiao Zhou, R. Schwartz, P. de Coppi, S. Rabbany, S. Rafii   +28 more
semanticscholar   +1 more source