Results 41 to 50 of about 72,062 (325)
Human Hepatocellular response in Cholestatic Liver Diseases
Primary biliary cholangitis (PBC) and primary sclerosing cholangitis (PSC), the most common types of cholestatic liver disease (CLD), result in enterohepatic obstruction, bile acid accumulation, and hepatotoxicity.
Kimberly Ortiz+9 more
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Decellularized scaffolds are promising biomaterials for tissue and organ reconstruction; however, strategies to effectively suppress the host immune responses toward these implants, particularly those without chemical crosslinking, remain warranted ...
Makoto Hisanaga+14 more
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The cotyledon represents one of the bases of classification within the plant kingdom, providing the name-giving difference between dicotyledonous and monocotyledonous plants. It is also a fundamental organ and there have been many reports of cotyledon mutants in many species. The use of these mutants where they have arisen in Arabidopsis has allowed us
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The Regeneration ofOrganogenesis [PDF]
We would like to welcome our readers to the regenerated Organogenesis and to share with you the reasoning behind the refocusing of this journal toward the development of tissues and organs as a future means to improve the health of patients.
Alejandro Soto-Gutierrez+1 more
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Modeling human hepato-biliary-pancreatic organogenesis from the foregut-midgut boundary
Organogenesis is a complex and interconnected process that is orchestrated by multiple boundary tissue interactions1–7. However, it remains unclear how individual, neighbouring components coordinate to establish an integral multi-organ structure. Here we
H. Koike+11 more
semanticscholar +1 more source
Cells with Many Talents: Lymphatic Endothelial Cells in the Brain Meninges
The lymphatic system serves key functions in maintaining fluid homeostasis, the uptake of dietary fats in the small intestine, and the trafficking of immune cells. Almost all vascularized peripheral tissues and organs contain lymphatic vessels. The brain
Irina Suárez, Stefan Schulte-Merker
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Mechanisms of ectodermal organogenesis
All ectodermal organs, e.g. hair, teeth, and many exocrine glands, originate from two adjacent tissue layers: the epithelium and the mesenchyme. Similar sequential and reciprocal interactions between the epithelium and mesenchyme regulate the early steps of development in all ectodermal organs.
Johanna Pispa, Irma Thesleff
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Bone morphogenetic proteins (BMPs) control many developmental and physiological processes, including skeleton formation and homeostasis. Previous studies in zebrafish revealed the crucial importance of proper BMP signaling before 48 h post-fertilization (
Thomas Windhausen+3 more
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mRNA methylation at the N6-position of adenosine (m6A) enables multiple layers of post-transcriptional gene control, often via RNA-binding proteins that use a YT521-B homology (YTH) domain for specific m6A recognition.
Laura Arribas-Hernández+7 more
semanticscholar +1 more source
Organogenesis and Development of the Liver [PDF]
Embryonic development of the liver has been studied intensely, yielding insights that impact diverse areas of developmental and cell biology. Understanding the fundamental mechanisms that control hepatogenesis has also laid the basis for the rational differentiation of stem cells into cells that display many hepatic functions. Here, we review the basic
Stephen A. Duncan+3 more
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