Results 41 to 50 of about 136,156 (356)

Adaptable haemodynamic endothelial cells for organogenesis and tumorigenesis

Nature, 2020
Endothelial cells adopt tissue-specific characteristics to instruct organ development and regeneration 1 , 2 . This adaptability is lost in cultured adult endothelial cells, which do not vascularize tissues in an organotypic manner.
Brisa Palikuqi, Duc-Huy T. Nguyen, Ge Li, Ryan Schreiner, A. Pellegata, Y. Liu, D. Redmond, F. Geng, Yang Lin, J. Gómez-Salinero, Masataka Yokoyama, P. Zumbo, Tuo Zhang, Balvir Kunar, Mavee Witherspoon, Teng Han, A. Tedeschi, F. Scottoni, S. Lipkin, L. Dow, O. Elemento, J. Xiang, K. Shido, J. Spence, Qiao Zhou, R. Schwartz, P. de Coppi, S. Rabbany, S. Rafii   +28 more
semanticscholar   +1 more source

Morphogenesis along the animal-vegetal axis: fates of primary quartet micromere daughters in the gastropod Crepidula fornicata. [PDF]

, 2017
BackgroundThe Spiralia are a large, morphologically diverse group of protostomes (e.g. molluscs, annelids, nemerteans) that share a homologous mode of early development called spiral cleavage.
Henry, Jonathan Q, Lyons, Deirdre C, Perry, Kimberly J   +2 more
core   +1 more source

Organogenesis

Chinese Medical Journal, 2019
This chapter focuses on organogenesis. It looks into the process of developing organs such as vertebrate eyes, vertebrate heart, teeth, vertebrate lungs, vertebrate limb, and insect wings. The chapter also highlights the complexity of organogenesis as it involves large numbers of genes and different types of tissues while ensuring integrated ...
Lewis Wolpert, Cheryll Tickle, Alfonso Martinez Arias, Peter Lawrence, James Locke   +4 more
openaire   +4 more sources

Sonic Hedgehog Signaling in Organogenesis, Tumors, and Tumor Microenvironments

International Journal of Molecular Sciences, 2020
During mammalian embryonic development, primary cilia transduce and regulate several signaling pathways. Among the various pathways, Sonic hedgehog (SHH) is one of the most significant. SHH signaling remains quiescent in adult mammalian tissues. However,
K. Jeng, Chiung-Fang Chang, Shuru Lin
semanticscholar   +1 more source

Auxin-Regulated Lateral Root Organogenesis.

Cold Spring Harbor Perspectives in Biology, 2021
Plant fitness is largely dependent on the root, the underground organ, which, besides its anchoring function, supplies the plant body with water and all nutrients necessary for growth and development.
N. Cavallari, Christina Artner, E. Benková   +2 more
semanticscholar   +1 more source

Clinical Manufacturing of Regulatory T Cell Products For Adoptive Cell Therapy and Strategies to Improve Therapeutic Efficacy

Organogenesis, 2023
Based on successes in preclinical animal transplant models, adoptive cell therapy (ACT) with regulatory T cells (Tregs) is a promising modality to induce allograft tolerance or reduce the use of immunosuppressive drugs to prevent rejection.
Kassandra J. Baron, Hēth R. Turnquist
doaj   +1 more source

Organogenesis in vitro

Current Opinion in Cell Biology, 2021
Organoids are three-dimensional structures that self-organize from human pluripotent stem cells or primary tissue, potentially serving as a traceable and manipulatable platform to facilitate our understanding of organogenesis. Despite the ongoing advancement in generating organoids of diverse systems, biological applications of in vitro generated ...
Kentaro Iwasawa, Takanori Takebe
openaire   +2 more sources

Plant Cellular and Molecular Biotechnology: Following Mariotti's Steps [PDF]

, 2019
This review is dedicated to the memory of Prof. Domenico Mariotti, who significantly contributed to establishing the Italian research community in Agricultural Genetics and carried out the first experiments of Agrobacterium-mediated plant genetic ...
Caretto, Sofia, Frugis, Giovanna, Giannino, Donato, Iannelli, Maria Adelaide, Mauro, Maria Luisa, Mele, Giovanni, Nicolodi, Chiara, Paolis, Angelo De, Rugini, Eddo, Silvestri, Cristian, Sparvoli, Francesca, Testone, Giulio   +11 more
core   +1 more source

Direct reprogramming of human umbilical vein- and peripheral blood-derived endothelial cells into hepatic progenitor cells

Nature Communications, 2020
The conditions to induce human hepatic progenitor cells from other cell types are unclear. Here, the authors reprogram human endothelial cells to hepatic progenitor cells by expressing FOXA3, HNF1A and HNF6, capable of giving rise to hepatocytes and ...
Hiroki Inada, Miyako Udono, Kanae Matsuda-Ito, Kenichi Horisawa, Yasuyuki Ohkawa, Shizuka Miura, Takeshi Goya, Junpei Yamamoto, Masao Nagasaki, Kazuko Ueno, Daisuke Saitou, Mikita Suyama, Yoshihiko Maehara, Wataru Kumamaru, Yoshihiro Ogawa, Sayaka Sekiya, Atsushi Suzuki   +16 more
doaj   +1 more source

Modeling human hepato-biliary-pancreatic organogenesis from the foregut-midgut boundary

Nature, 2019
Organogenesis is a complex and interconnected process that is orchestrated by multiple boundary tissue interactions1–7. However, it remains unclear how individual, neighbouring components coordinate to establish an integral multi-organ structure. Here we
H. Koike, K. Iwasawa, Rie Ouchi, Mari Maezawa, Kirsten B. Giesbrecht, Norikazu Saiki, Autumn Ferguson, M. Kimura, Wendy L Thompson, James M. Wells, A. Zorn, T. Takebe   +11 more
semanticscholar   +1 more source