Results 51 to 60 of about 72,062 (325)

Organogenesis of the endocrine pancreas [PDF]

open access: yesKidney International, 2005
Organogenesis of the endocrine pancreas. Embryonic pancreatic primordia transplanted into diabetic animal hosts undergo selective endocrine differentiation in situ and normalize glucose tolerance. Pancreatic primordia can be transplanted across isogeneic, allogeneic, and both concordant (rat to mouse) and highly disparate (pig to rodent) xenogeneic ...
openaire   +3 more sources

Progress in the Application of Organoids-On-A-Chip in Diseases

open access: yesOrganogenesis
With the rapid development of the field of life sciences, traditional 2D cell culture and animal models have long been unable to meet the urgent needs of modern biomedical research and new drug development.
Qiao Geng   +6 more
doaj   +1 more source

Discovering Novel Bioactivities of Controversial Food Additives by Means of Simple Zebrafish Embryotoxicity (ZET) Assays

open access: yesToxics, 2022
The rising concerns about controversial food additives’ potential hazardous properties require extensive yet animal-minimized testing strategies. Zebrafish embryos are the ideal in vivo model representing both human and environmental health.
Dinh Duy-Thanh   +4 more
doaj   +1 more source

Role of VEGF in Organogenesis [PDF]

open access: yesOrganogenesis, 2008
The cardiovascular system, consisting of the heart, blood vessels and hematopoietic cells, is the first organ system to develop in vertebrates and is essential for providing oxygen and nutrients to the embryo and adult organs. Work done predominantly using the mouse and zebrafish as model systems has demonstrated that Vascular Endothelial Growth Factor
openaire   +3 more sources

Root nodule organogenesis: a unique lateral organogenesis in legumes

open access: yesBreeding Science, 2023
During the course of plant evolution, leguminous and a few plants species have established root nodule symbiosis (RNS), one of the nitrogen nutrient acquisition strategies based on mutual interaction between plants and nitrogen-fixing bacteria. In addition to its useful agronomic trait, RNS comprises a unique form of plant lateral organogenesis ...
openaire   +2 more sources

Cytoskeleton and plant organogenesis [PDF]

open access: yesPhilosophical Transactions of the Royal Society of London. Series B: Biological Sciences, 2002
The functions of microtubules and actin filaments during various processes that are essential for the growth, reproduction and survival of single plant cells have been well characterized. A large number of plant structural cytoskeletal or cytoskeleton–associated proteins, as well as genes encoding such proteins, have been identified.
Yi-Qun Bao, Benedikt Kost, Nam-Hai Chua
openaire   +2 more sources

Cyborg Organoids: Implantation of Nanoelectronics via Organogenesis for Tissue-Wide Electrophysiology

open access: yesbioRxiv, 2019
Tissue-wide electrophysiology with single-cell and millisecond spatiotemporal resolution is critical for heart and brain studies, yet issues arise from invasive, localized implantation of electronics that destructs the well-connected cellular networks ...
Qiang Li   +6 more
semanticscholar   +1 more source

The thioredoxin‐like and one glutaredoxin domain are required to rescue the iron‐starvation phenotype of HeLa GLRX3 knock out cells

open access: yesFEBS Letters, EarlyView.
Glutaredoxin (Grx) 3 proteins contain a thioredoxin domain and one to three class II Grx domains. These proteins play a crucial role in iron homeostasis in eukaryotic cells. In human Grx3, at least one of the two Grx domains, together with the thioredoxin domain, is essential for its function in iron metabolism.
Laura Magdalena Jordt   +4 more
wiley   +1 more source

Hepatocytes differentiate into intestinal epithelial cells through a hybrid epithelial/mesenchymal cell state in culture

open access: yesNature Communications
Hepatocytes play important roles in the liver, but in culture, they immediately lose function and dedifferentiate into progenitor-like cells. Although this unique feature is well-known, the dynamics and mechanisms of hepatocyte dedifferentiation and the ...
Shizuka Miura   +9 more
doaj   +1 more source

The Interactivity between TGFβ and BMP Signaling in Organogenesis, Fibrosis, and Cancer

open access: yesCells, 2019
The Transforming Growth Factor beta (TGFβ) and Bone Morphogenic Protein (BMP) pathways intersect at multiple signaling hubs and cooperatively or counteractively participate to bring about cellular processes which are critical not only for tissue ...
F. Dituri   +3 more
semanticscholar   +1 more source

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