Results 191 to 200 of about 90,274 (350)

A High Content Imaging and Machine Learning Approach to Identify the Anti-Cancer Effect of Novel Small Molecules on Brain Cancer Patient-Derived Organoids [PDF]

Rizwan Ali, Yassinali Tamboli, Saba M. Alsubaie, Sikander Hayat, Mohamed Boudjelal   +4 more
openalex   +1 more source

Brain organoids and Ó?organoid intelligenceÓ�: a neuroethical critique

Bioethics Update
Background: The article “Brain organoids and ‘organoid intelligence’” delves into the cutting-edge research surrounding the cultivation and utilization of brain organoids. It highlights the potential of these miniaturized, simplified versions of the brain to revolutionize our understanding of neural development, disease mechanisms, and neurophysiology.
openaire   +2 more sources

Advanced Mounting Technique for Improved Imaging and Analysis of Embedded Spheroids and Migrating Cells in Light Sheet Fluorescence Microscopy

Advanced Materials Technologies, EarlyView.
A novel sample holder compatible with the Zeiss Lightsheet 7 microscope improves imaging of spheroids embedded in collagen matrices. By enabling dual‐sided illumination, it enhances image quality and quantitative analysis of migrating cells. This method advances 3D light sheet microscopy for studying tumor invasion and therapeutic responses.
Masoumeh Mohamadian Namaqi, Franziska Moll, Robert Römer, Andreas Grodrian, Doris Heinrich, Karen Lemke   +5 more
wiley   +1 more source

An Integrative Roadmap for Advancing Colorectal Cancer Organoid. [PDF]

Biomedicines
Zhu Y, He K, Shi Z.
europepmc   +1 more source

Epithelial Reprogramming by OM-89 Enhances Antibiotic Clearance of Uropathogenic E. coli in a Bladder Organoid Model [PDF]

Kathrin Tomasek, Kristina Skurvydaite, Gauri Paduthol, Allison M. Burns, Léa Ivana Esméralda Schlunke, Christian Pasquali, Mario Romani, John D. McKinney   +7 more
openalex   +1 more source

Nanoporous Microelectrodes for Neural Electrophysiology Recordings in Organotypic Culture

Advanced Materials Technologies, EarlyView.
The highly porous microelectrodes have been designed and printed on culture membranes, allowing to record electrophysiological neural activity for rodent brain slices. To keep the biocompatible nanoporous structure, the microelectrodes and insulative layer are fabricated on the bottom of culture membranes with only small connector pads added on the top.
Petro Lutsyk, Debjani Goswami, Stephen Worrall, Stuart D. Greenhill   +3 more
wiley   +1 more source

Necessary, Legendary and Detrimental Components of Human Colorectal Organoid Culture Medium: Raising Awareness to Reduce Experimental Bugs. [PDF]

Cancers (Basel)
Benelli R.
europepmc   +1 more source

Utilizing human tonsil organoids to identify host and antigen correlates of protection to influenza vaccines 3311 [PDF]

Zach W. Wagoner, Timothy B. Yates, Jenny E. Davies, Suhas Sureshchandra, Erika Joloya, Aarti Jain, Rafael de Assis, Jenna M. Kastenschmidt, Andrew M. Sorn, Mahina Tabassum Mitul, Ian Tamburini, Gurpreet S. Ahuja, Qiu Zhong, Douglas K. Trask, Marcus Seldin, D. Huw Davies, Lisa E. Wagar   +16 more
openalex   +1 more source

BLOC: Buildable and Linkable Organ on a Chip

Advanced Materials Technologies, EarlyView.
We developed a “Buildable and Linkable Organ on a Chip” (BLOC) that can construct diverse microphysiological systems (MPSs). The BLOC is standardized to the same size and has one of the functions of “Culture,” “Control,” or “Analysis.” Users can freely configure various MPSs, including developing perfusion, cytotoxicity analysis, and biochemical ...
Yusuke Kimura, Hiroki Hamaguchi, Kotaro Oyama, Tomoko G. Oyama, Atsushi Kimura, Yasuhiro Ohshima, Noriko S. Ishioka, Mitsumasa Taguchi   +7 more
wiley   +1 more source

Organoids for disease modeling and treatment: state-of-the-art. [PDF]

Exp Hematol Oncol
Xu M, Kong D, Sun S, Wang Y, Su G, Zhang S, Yan J, Han Z, Li J, Zhang L.   +9 more
europepmc   +1 more source