Results 201 to 210 of about 114,312 (393)

Microphysiological Systems of Lymphatics and Immune Organs

open access: yesAdvanced Healthcare Materials, EarlyView.
This review surveys recent progress in engineering lymphatic microenvironments and immune organoids within microphysiological systems, emphasizing innovative strategies to recreate the biochemical and biophysical complexity of native lymphatic tissues.
Ishita Jain   +2 more
wiley   +1 more source

ECM-based molecular subtypes define prognostic, EMT status, and therapeutic diversity in IDH-mutant gliomas

open access: yesnpj Precision Oncology
IDH-mutant gliomas show prognostic heterogeneity despite favorable overall outcomes, necessitating refined molecular classification. While the extracellular matrix (ECM) critically regulates tumor progression, immunity, and EMT, its prognostic ...
Yanfei Wei   +10 more
doaj   +1 more source

Advances in biomarkers and diagnostic significance of organ aging

open access: yesFundamental Research
A complete understanding of aging is a critical first step in treating age-related diseases and postponing aging dysfunction in the context of an aging global population.
Yulin Chen   +5 more
doaj   +1 more source

Two cases of basal cell epithelioma on organoid nevus.

open access: bronze, 1997
Masahiro Amano   +2 more
openalex   +2 more sources

Brain organoids and Ó?organoid intelligenceÓ�: a neuroethical critique

open access: yesBioethics Update
Background: The article “Brain organoids and ‘organoid intelligence’” delves into the cutting-edge research surrounding the cultivation and utilization of brain organoids. It highlights the potential of these miniaturized, simplified versions of the brain to revolutionize our understanding of neural development, disease mechanisms, and neurophysiology.
openaire   +2 more sources

Development of a Synthetic 3D Platform for Compartmentalized Kidney In Vitro Disease Modeling

open access: yesAdvanced Healthcare Materials, EarlyView.
A fully synthetic, compartmentalized 3D kidney disease model is introduced. The kidney model combines a PEG‐based hydrogel matrix with anisotropic, enzymatically degradable rod‐shaped microgels to spatially arrange a triple co‐culture of key renal epithelial, endothelial, and fibroblast cells.
Ninon Möhl   +8 more
wiley   +1 more source

Progressive Insights into 3D Bioprinting for Corneal Tissue Restoration

open access: yesAdvanced Healthcare Materials, EarlyView.
This review explores the potential of 3D bioprinting to replicate the complex structure and function of the human cornea. It highlights key advances in bioink development, printing modalities, and in vivo performance, while addressing current challenges and emerging strategies. The review emphasizes bioprinting's promise to overcome donor shortages and
Ilayda Namli   +6 more
wiley   +1 more source

Biomimetic Fibrinogen Nanofiber Scaffolds for Vascular Hematopoietic Stem Cell Niche Engineering

open access: yesAdvanced Healthcare Materials, EarlyView.
This study presents an advanced in vitro model of the vascular hematopoietic stem cell niche using self‐assembled fibrinogen nanofibers, mimicking the basement membrane in bone marrow (BM) sinusoids. The model supports the coculture of microvascular endothelial cells, stromal cells, and hematopoietic stem and progenitor cells, providing insights into ...
Sophia Lena Meermeyer   +4 more
wiley   +1 more source

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