Results 131 to 140 of about 1,044,908 (274)
iMetaMed, EarlyView.The occurrence and progression of colorectal cancer are intricately linked to metabolites produced by the gut microbiota. Metabolites generated by pathogenic microbial communities can promote colorectal cancer development by reshaping the immune microenvironment.
Xinrui Yang +3 more
wiley +1 more source
iMetaMed, EarlyView.Pyridoxal (PL) exhibits the strongest anti‐tumor activity within the vitamin B6 family, demonstrating significant ovarian cancer cell‐killing efficacy in vivo, in vitro, and in patient‐derived organoid (PDO) models. The anti‐tumor mechanism involves PL inducing a shift in peroxisome dynamics towards fission, promoting peroxisome proliferation, and ...
Ruonan Li +12 more
wiley +1 more source
Encoding Tactile Stimuli for Organoid Intelligence in Braille Recognition
This study proposes a generalizable encoding strategy that maps tactile sensor data to electrical stimulation patterns, enabling neural organoids to perform an open-loop artificial tactile Braille classification task. Human forebrain organoids cultured on a low-density microelectrode array (MEA) are systematically stimulated to characterize the ...
Liu, Tianyi +2 more
openaire +2 more sources
Microbial metabolites in tumor epigenetic regulation
iMeta, EarlyView.The gut microbiome modulates tumor epigenetic regulation through bioactive metabolites derived from dietary substrates. Microbiota‐produced SCFAs, secondary BAs, one‐carbon metabolites, and tryptophan‐derived ligands regulate histone acetylation, DNA methylation, and chromatin remodeling via HDAC, DNMT, AhR, and metabolic cofactor‐dependent pathways ...
Wangzheqi Zhang +31 more
wiley +1 more source
The Donation of Human Biological Material for Brain Organoid Research: The Problems of Consciousness and Consent [PDF]
脳を作る研究への細胞提供 --細胞提供者を守るための研究者への提言--. 京都大学プレスリリース. 2024-02-27.Proposals for cell donation procedures to create brain organoids. 京都大学プレスリリース. 2024-02-29.Human brain organoids are three-dimensional masses of tissues derived from human stem cells that ...
Gyngell, Christopher +3 more
core +2 more sources
iNew Medicine, EarlyView.This review traces the evolution of functional biliary stents, outlining the paradigm shift from “active intervention” strategies that target stent failure to next‐generation “enabling platforms.” These platforms leverage biodegradable materials, 3D/4D printing, and smart sensors to achieve personalized, regenerative, and theranostic solutions ...
Muhan Li +4 more
wiley +1 more source
Nanobiosensors for monitoring of stem-cell differentiation and organoids
Frontiers in NanotechnologyNanobiosensors now allow continuous, nondestructive tracking of stem cell differentiation and organoid maturation. Classical assays such as immunostaining and polymerase chain reaction are invasive snapshots that overlook fast molecular events guiding ...
Young Hoon Son, Gun-Jae Jeong
doaj +1 more source
Organoid bioinks: construction and application
BiofabricationOrganoids have emerged as crucial platforms in tissue engineering and regenerative medicine but confront challenges in faithfully mimicking native tissue structures and functions.
Fuxiao Wang +6 more
semanticscholar +1 more source
Aerospace medicine and biology: A continuing bibliography with indexes (supplement 338) [PDF]
This bibliography lists 139 reports, articles and other documents introduced into the NASA Scientific and Technical Information System during June 1990.
core +1 more source
iNew Medicine, EarlyView.ABSTRACT Ovarian cancer (OC) continues to be the deadliest gynecological malignancy and a significant cause of cancer‐related mortality among women worldwide. Standard treatment strategies typically entail platinum‐based chemotherapy in conjunction with cytoreductive surgery.
Zunera Khalid +4 more
wiley +1 more source