Results 11 to 20 of about 2,401,578 (298)

The Baltimore declaration toward the exploration of organoid intelligence [PDF]

Frontiers in Science, 2023
CITATION Hartung T, Smirnova L, Morales Pantoja IE, Akwaboah A, Alam El Din D-M, Berlinicke CA, Boyd JL, Caffo BS, Cappiello B, Cohen-Karni T, Curley JL, Etienne-Cummings R, Dastgheyb R, Gracias DH, Gilbert F, Habela CW, Han F, Harris TD, Herrmann K ...
T. Hartung, L. Smirnova, Itzy E. Morales Pantoja, A. Akwaboah, Dowlette-Mary Alam El Din, C. Berlinicke, J. Boyd, B. Caffo, Ben Cappiello, Tzahi Cohen-Karni, J. Curley, R. Etienne-Cummings, Raha M. Dastgheyb, D. Gracias, Frederic Gilbert, C. Habela, Fang Han, Timothy D. Harris, Kathrin Herrmann, Eric Hill, Qi Huang, R. Jabbour, E. Johnson, Brett J. Kagan, C. Krall, A. Levchenko, P. Locke, A. Maertens, Monica R. Metea, A. Muotri, R. Parri, B. Paulhamus, J. Plotkin, Paul Roach, J. C. Romero, J. Schwamborn, F. Sillé, A. Szalay, K. Tsaioun, D. Tornero, J. Vogelstein, K. Wahlin, D. Zack   +42 more
semanticscholar   +5 more sources

From Brain Organoids to Organoid Intelligence. Benefits and Ethical-Moral Framework

Current Stem Cell Reports
Organoid intelligence (OI) is an emerging field in biological computing that integrates brain organoids with external interfaces capable of receiving and transmitting signals.
René García-Contreras
exaly   +3 more sources

Organoid intelligence (OI): the new frontier in biocomputing and intelligence-in-a-dish [PDF]

Frontiers in Science, 2023
Recent advances in human stem cell-derived brain organoids promise to replicate critical molecular and cellular aspects of learning and memory and possibly aspects of cognition in vitro.
L. Smirnova, B. Caffo, D. Gracias, Qi Huang, Itzy E. Morales Pantoja, Bohao Tang, D. Zack, C. Berlinicke, J. Boyd, T. Harris, E. C. Johnson, Brett J. Kagan, Jeffrey Kahn, A. Muotri, B. Paulhamus, J. Schwamborn, J. Plotkin, Alexander S. Szalay, J. Vogelstein, P. Worley, T. Hartung   +20 more
semanticscholar   +2 more sources

Organoid intelligence (OI) - The ultimate functionality of a brain microphysiological system.

ALTEX, 2023
Understanding brain function remains challenging as work with human and animal models is complicated by compensatory mechanisms, while in vitro models have been too simple until now.
L. Smirnova, Itzy E. Morales Pantoja, T. Hartung   +2 more
semanticscholar   +4 more sources

Brain organoids and “organoid intelligence”: a neuroethical critique

Bioethics Update
Background: The article “Brain organoids and ‘organoid intelligence’” delves into the cutting-edge research surrounding the cultivation and utilization of brain organoids.
Alberto Carrara
doaj   +2 more sources

Colorectal cancer organoids: a developmental trajectory from Matrigel embedding to AI-empowered precision medicine [PDF]

Frontiers in Oncology
The high heterogeneity and complex microenvironment of colorectal cancer (CRC) represent critical bottlenecks contributing to treatment resistance and clinical translation failure, and the iterative development of organoid technology provides a key ...
Muxin Tang, Lin Shaoyi, Qian Liang, Di Long   +3 more
doaj   +2 more sources

AI‐organoid integrated systems for biomedical studies and applications

Bioengineering & Translational Medicine
In this review, we explore the growing role of artificial intelligence (AI) in advancing the biomedical applications of human pluripotent stem cell (hPSC)‐derived organoids.
Sudhiksha Maramraju, Andrew Kowalczewski, Anirudh Kaza, Xiyuan Liu, Jathin Pranav Singaraju, Mark V. Albert, Zhen Ma, Huaxiao Yang   +7 more
doaj   +2 more sources

Artificial Intelligence–Enabled Organoid Platforms for Precision Medicine: Integrating Multi-Omics, Digital Twins, and Microphysiological Systems

Organoids
The convergence of artificial intelligence (AI) and organoid technology represents a transformative advance toward precision and predictive medicine. Organoids derived from pluripotent stem cells or patient tissues provide physiologically relevant three ...
Ramandeep Saini, Bishakha Thakur, Bikram Kumar Basaba, Mantosh Kumar Satapathy   +3 more
doaj   +2 more sources

Inflammasomes meet organoids and artificial intelligence: unraveling the complexity of gynecological inflammation [PDF]

Frontiers in Immunology
Gynecological diseases represent a persistent global health burden. According to a WHO report, the global incidence of gynecological diseases exceeds 65%. Furthermore, over 90% of women suffer from gynecological issues to varying degrees.
Lanyue Zhang, Jiangnan Zhao, Guanghui Cheng, Jiaxin Wu, Yunhao Liu, Guo Lei, Qin Wang   +6 more
doaj   +2 more sources

Artificial intelligence-, organoid-, and organ-on-chip-powered models to improve pre-clinical animal testing of vaccines and immunotherapeutics: potential, progress, and challenges

Frontiers in Artificial Intelligence
Vaccines and immunotherapies against infectious diseases and cancers have been a great success of the medical sciences over the last century.
Sweta Karan
exaly   +2 more sources