Results 111 to 120 of about 65,212 (162)

Human organoids: Fit for drug discovery? [PDF]

Stem Cell Reports
Wittich A, Krieg K, Gribbon P, Metzger JJ, Prigione A, Pless O.   +5 more
europepmc   +1 more source

Urolithin A activates aryl hydrocarbon receptor-NLRP6-mediated pathways in intestinal epithelial cells to modulate mucosal immunity and strengthen gut barrier integrity. [PDF]

Nat Commun
Ghosh S, Vanwinkle ZM, Bodduluri SR, Juin SK, Kadari M, Singh A, Dryden GW, Lawrenz MB, Kanneganti TD, Rai SN, Good M, Kumar P, Haribabu B, Jala VR.   +13 more
europepmc   +1 more source

Mouse Lacrimal Gland Ductal Organoids With Controlled Polarity: A Novel Ex Vivo Research Model. [PDF]

Invest Ophthalmol Vis Sci
Csapó V, Elekes G, Tálosi D, Török D, Bellák T, Tóth-Molnár E.   +5 more
europepmc   +1 more source

Advances and future perspectives of kidney organoid technology in renal disease research and clinical translation. [PDF]

Front Med (Lausanne)
Zhao Z, Tong K, Deng K, Liu H, Li Y, Wang D.   +5 more
europepmc   +1 more source

An appendiceal cancer organoid biobank identifies phenotypic evolution and druggable dependencies of peritoneal carcinomatosis. [PDF]

Dev Cell
Mahmoud A, Sukhwa C, Giarrizzo M, Choi PH, Pintar J, Walch H, Zhao N, Bermeo J, Chung S, Raghavan M, Bapat S, Jiang Q, Meredith J, Firat C, Cercek A, Foote MB, Schultz N, Chatila WK, Nash GM, Shia J, Sanchez-Vega F, Larson S, Dar AC, Rosen N, Karagkounis G, Ganesh K.   +25 more
europepmc   +1 more source

Comparative analysis of zebrafish, organoid, and organ-on-chip models in breast cancer research. [PDF]

Biotechnol Notes
Alzaharani R, Alghadmi MA, Amiri M.
europepmc   +1 more source

Opportunities and challenges in studying non-coding RNAs using neural organoid models. [PDF]

Front Mol Neurosci
Chiang PS, Tsai MH, Hou PS.
europepmc   +1 more source

A patient-derived organoid model identifies TP53-dependent gemcitabine sensitivity in spinal chordoma. [PDF]

Discov Oncol
Hu P, Zeng S, Lei J, Zhou H, Wang B, Liu Z, Liu X, Wei F.   +7 more
europepmc   +1 more source

Induction of fibrosis in human kidney organoids delineates mechanisms and therapeutic targets of fibrotic kidney disease. [PDF]

Stem Cell Res Ther
Doeser MC, Raimann J, Beuke M, Kilcan Z, Menke AF, Klinkhammer BM, Boor P, Schöler HR, Pavenstädt H.   +8 more
europepmc   +1 more source

Integrated mesenchymal and extracellular cues drive bioengineered liver tissue formation and function. [PDF]

Mater Today Bio
Ye S, Wang Z, Dirk Delemarre M, Liv N, van den Dikkenberg A, Vermonden T, van der Laan L, Malda J, Spee B, G Van Steenbeek F, Schneeberger-Verjaal K.   +10 more
europepmc   +1 more source