Results 91 to 100 of about 7,059 (201)

Assessment of enzyme inhibition : a review with examples from the development of monoamine oxidase and cholinesterase inhibitory drugs [PDF]

, 2017
Both authors are grateful for the collaborations on multi-target drugs facilitated by COST Action CM1103 (2011-2015).The actions of many drugs involve enzyme inhibition.
Ramsay, Rona R., Tipton, Keith F.
core   +1 more source

Report of the Scientific Committee of the Spanish Agency for Food Safety and Nutrition (AESAN) on nutritional risks for women during menopause, perimenopause and postmenopause

Food Risk Assess Europe, Volume 4, Issue 2, April 2026.
Abstract Menopause is the time when a woman transitions from the reproductive stage of life to the non‐reproductive state. It is characterised by significant hormonal changes, which can affect a woman's physical, emotional, mental and social well‐being.
Irene Bretón Lesmes, Concepción María Aguilera García, Araceli Díaz Perales, Ángel Gil Izquierdo, Gema Nieto Martínez, Ana María Rivas Velasco, Virginia Arianna Aparicio García‐Molina, María Ángeles Carlos Chillerón   +7 more
wiley   +1 more source

Substrate Analogues for the Enzyme-Catalyzed Detoxification of the Organophosphate Nerve Agents-Sarin, Soman, and Cyclosarin. [PDF]

Biochemistry, 2021
Bigley AN, Harvey SP, Narindoshvili T, Raushel FM.   +3 more
europepmc   +1 more source

Atropine Use in Children After Nerve Gas Exposure [PDF]

, 2004
Following the FDA's approval of a pediatric dosage Atropen®, the Pediatric Expert Advisory Panel was asked to review the existing guidelines and recommendations regarding the treatment of children exposed to nerve agents and the Mark-1 Kit; review the ...
National Center for Disaster Preparedness
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Socio-Demographic Profiling Of Organophosphorus Pesticides Poisoning Reported To National Poison Centre Of Malaysia Between Year 2006 To 2015 [PDF]

, 2017
Keracunan dan kesan negatif terhadap kesihatan manusia akibat penggunaan racun makhluk perosak daripada bahan organofosforus telah dikaji secara meluas dan berterusan oleh para saintis Toxicity of organophosphorus compound pesticides towards human ...
Abdullah, Zuraini
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Pyrethroid insecticide exposure and cognitive developmental disabilities in children: The PELAGIE mother–child cohort

, 2015
International audiencePyrethroid insecticides are widely used in agriculture and in homes. Despite the neurotoxicity of these insecticides at high doses, few studies have examined whether lower-level exposures could adversely affect children's ...
Chevrier, Cécile, Cordier, Sylvaine, Durand, Gaël, Lacroix, Agnès, Le Maner-Idrissi, Gaïd, Limon, Gwendolina, Monfort, Christine, Rouget, Florence, Viel, Jean-François, Warembourg, Charline   +9 more
core   +4 more sources

A case report and overview of Carbamate insecticide (Baygon) poisoning [PDF]

, 2017
The following is a case report of a 55-year-old gentleman who experienced excessive exposure to Baygon® , a local carbamate insecticide spray. He developed symptoms that were compatible with cholinesterase inhibition, namely headache, light-headedness ...
Attard, Marlene, Muscat, Peter
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Cholesterol Oxime Olesoxime Assessed as a Potential Ligand of Human Cholinesterases

Biomolecules
Olesoxime, a cholesterol derivative with an oxime group, possesses the ability to cross the blood–brain barrier, and has demonstrated excellent safety and tolerability properties in clinical research.
Dora Kolić, Goran Šinko, Ludovic Jean, Mourad Chioua, José Dias, José Marco-Contelles, Zrinka Kovarik   +6 more
doaj   +1 more source

Dual targeting of iNOS and Src tyrosine kinase as a superior therapeutic strategy against soman-induced long-term neurotoxicity: multimodal biomarker, imaging, and neurobehavioral outcome analyses

Acta Neuropathologica Communications
Acute exposure to the organophosphate nerve agent (OPNA) soman (GD) triggers severe and persistent brain injury characterized by seizures, oxidative stress, and structural and functional network alterations, collectively described as the brain’s “SOS ...
Nyzil Massey, Suraj S. Vasanthi, Christina Meyer, Nikhil S. Rao, Daniel R. Thedens, Chong Wang, Sridhar Kannurpatti, Thimmasettappa Thippeswamy   +7 more
doaj   +1 more source

Management of Treatment and Prevention of Acute OP Pesticide Poisoning by Medical Informatics, Telemedicine and Nanomedicine [PDF]

, 2013
Acute organophosphorous pesticide (OP) poisoning kills a lot of people each year. Treatment of acute OP poisoning is of very difficult task and is a time taking event.
Anurag Singh Chauhan, Ganesh Chandra Sahoo, Krishna Pandey, Kumar Gaurav, Manas Ranjan Dikhit, Md. Yousuf Ansari, Mukta Rani, Naresh Kumar Sinha, Pradeep Das, Rishikesh Kumar, Roshan Kamal Topno, Sindhuprava Rana, Vahab Ali, Vidyananda Ravi Das   +13 more
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