Assessment of Intramuscular Verapamil as Pharmacological Countermeasure in a Rat Model of Organophosphate DFP-induced Status Epilepticus. [PDF]
Paudel YN +9 more
europepmc +1 more source
Graphene-Based Sensors and Biosensors Fabricated via Pulsed Laser Deposition for Chemical and Biological Threat Detection: A Comprehensive Roadmap. [PDF]
Kreusch Filho D +4 more
europepmc +1 more source
Accidental Organophosphate Poisoning in a Patient Due to a Bed Bug Pesticide in the United Kingdom: A Case Report. [PDF]
Griffiths D +4 more
europepmc +1 more source
Case Report: Dropped head syndrome as a main clinical sign of suspected myasthenia gravis in two dogs. [PDF]
Reyes HM +5 more
europepmc +1 more source
Advances in the Molecular Mechanisms of Resistance in <i>Chilo suppressalis</i>. [PDF]
Ge W, Chen G, Wang M, Wu S, Gao C.
europepmc +1 more source
Environmentally Friendly Nanocoating for Rapid Detection of Nerve Agents on Textile Fabric. [PDF]
Jordanov I +3 more
europepmc +1 more source
Neurosteroid mitigation of developmental neurological dysfunction, long-term epileptic biomarkers, chronic neuroinflammation, and neurodegeneration in a pediatric rat model of organophosphate exposure. [PDF]
Ramakrishnan S +4 more
europepmc +1 more source
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Microchip enzymatic assay of organophosphate nerve agents
Analytica Chimica Acta, 2004Abstract An on-chip enzymatic assay for screening organophosphate (OP) nerve agents, based on a pre-column reaction of organophosphorus hydrolase (OPH), electrophoretic separation of the phosphonic acid products, and their contactless-conductivity detection, is described.
Joseph Wang +5 more
openaire +3 more sources
Bacterial detoxification of organophosphate nerve agents
Current Opinion in Microbiology, 2002Bacterial enzymes have been isolated that catalyze the hydrolysis of organophosphate nerve agents with high-rate enhancements and broad substrate specificity. Mutant forms of these enzymes have been constructed through rational redesign of the active-site binding pockets and random mutagenesis to create protein variants that are optimized for the ...
Frank M Raushel
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Degradation of nerve agents by an organophosphate-degrading agent (OpdA)
Journal of Hazardous Materials, 2008Enzyme-catalysed degradation of the nerve agents tabun, sarin, ethyl sarin and soman by three variants of an organophosphate-degrading enzyme was studied at low concentrations of nerve agent. The concentration of nerve agent at a given time was determined by its ability to inhibit the enzyme acetylcholinesterase.
R M, Dawson +3 more
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