Results 171 to 180 of about 7,059 (201)

Bioanalysis of organophosphate nerve agents in soil samples

Chemosphere, 1993
Abstract Four soil samples that may have been spiked with chemical warfare (CW) agents and their degradation products were received by Defence Research Establishment Suffield as part of a multinational round-robin exercise designed to evaluate laboratory methodologies for the chemical detection of CW agents in soil.
T.W. Sawyer, M.T. Weiss
openaire   +1 more source

Anticholinesterase activity of organophosphate nerve agents in neuronal tissue culture

Toxicology in Vitro, 1992
Primary chick embryo forebrain culture was examined with respect to its usefulness as a model to study organophosphate (OP) anticholinesterases. The acetylcholinesterase (AChE) activity of these cultures increased with time in culture and paralleled the development in ovo of this enzyme.
T W, Sawyer, M T, Weiss, R J, Unger
openaire   +2 more sources

Selective detection of organophosphate nerve agents using microplasma device

Anal. Methods, 2014
A newly designed microplasma device can detect two parts of the nerve agent components simultaneously which enhances the selectivity in analysis.
Bo Wang, Wenqing Cao, Yixiang Duan
openaire   +1 more source

Bioassay of organophosphate nerve agents in soil using neuronal tissue cultures

Journal of Applied Toxicology, 1992
AbstractA soil sample originating from an area of suspected chemical warfare activity was subjected to chemical analysis and bioassay. Sarin and several related compounds were confirmed in the soil by capillary column gas chromatography–mass spectrometry (GC–MS); however, the binding of these compounds to the soil hindered quantitation.
T W, Sawyer, M T, Weiss, P A, D'Agostino, L R, Provost, J R, Hancock   +4 more
openaire   +2 more sources

Capillary Electrophoresis Microchips for Separation and Detection of Organophosphate Nerve Agents

Analytical Chemistry, 2001
A miniaturized analytical system for separating and detecting toxic organophosphate nerve agent compounds, based on the coupling of a micromachined capillary electrophoresis chip with a thick-film amperometric detector, is described. Factors influencing the on-chip separation and detection processes have been optimized.
J, Wang, M P, Chatrathi, A, Mulchandani, W, Chen   +3 more
openaire   +2 more sources

Fiber-Optic Enzyme Biosensor for Direct Determination of Organophosphate Nerve Agents

Biotechnology Progress, 1999
A fiber-optic enzyme biosensor for the direct measurement of organophosphate nerve agents was developed. The basic element of this biosensor is organophosphorus hydrolase immobilized on a nylon membrane and attached to the common end of a bifurcated optical fiber bundle.
A, Mulchandani, S, Pan, W, Chen
openaire   +2 more sources

Flow Injection Amperometric Enzyme Biosensor for Direct Determination of Organophosphate Nerve Agents

Environmental Science & Technology, 2001
A flow injection amperometric biosensor for the determination of organophosphate nerve agents was developed. The biosensor incorporated an immobilized enzyme reactor that contains the enzyme organophosphorus hydrolase covalently immobilized on activated aminopropyl controlled pore glass beads and an electrochemical flow-through detector containing ...
P, Mulchandani, W, Chen, A, Mulchandani
openaire   +2 more sources

Photonic crystal sensor for organophosphate nerve agents utilizing the organophosphorus hydrolase enzyme

Analytical and Bioanalytical Chemistry, 2007
We developed an intelligent polymerized crystalline colloidal array (IPCCA) photonic crystal sensing material which reversibly senses the organophosphate compound methyl paraoxon at micromolar concentrations in aqueous solutions. A periodic array of colloidal particles is embedded in a poly-2-hydroxyethylacrylate hydrogel.
Jeremy P, Walker, Kyle W, Kimble, Sanford A, Asher   +2 more
openaire   +2 more sources

Detoxification of organophosphate nerve agents by immobilizedEscherichia coli with surface-expressed organophosphorus hydrolase

Biotechnology and Bioengineering, 1999
An improved whole-cell technology for detoxifying organophosphate nerve agents was recently developed based on genetically engineered Escherichia coli with organophosphorus hydrolase anchored on the surface. This article reports the immobilization of these novel biocatalysts on nonwoven polypropylene fabric and their applications in detoxifying ...
A, Mulchandani, I, Kaneva, W, Chen
openaire   +2 more sources

Detection of Toxic Organophosphate Nerve Agents Using DBR Porous Silicon Chip

Solid State Phenomena, 2007
The efficient detection method based on nanostructured photonic DBR PSi has been developed for DMMP, which is a simulant for G-type nerve agents. The manufactured DBR PSi chip exhibits a sharp photonic band gap at 520 nm. The detection method involves the shift of DBR peak in reflectivity spectra under the exposure of vapors of analyte. Rapid detection
Bong Ju Lee, Seung Hyun Jang, Hong Lae Sohn   +2 more
openaire   +1 more source