Chemical weapon in the 20th and 21st centuries. Part 3. Organophosphorus chemical warfare agents used until the year 1970. V-group [PDF]
Biuletyn Wojskowej Akademii Technicznej, 2020 The article contains the knowledge about the V-group of organophosphorus chemical warfare agents, named nerve agents, used since their discovery until the year 1970.
Marcin Kloske, Zygfryd Witkiewicz
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Nerve Agent Hydrolysis Activity Designed into a Human Drug Metabolism Enzyme [PDF]
, 2010 Organophosphorus (OP) nerve agents are potent suicide inhibitors of the essential neurotransmitter-regulating enzyme acetylcholinesterase. Due to their acute toxicity, there is significant interest in developing effective countermeasures to OP ...
Andrew C. Hemmert +15 more
core +6 more sources
A sweet emergency due to bitter poisoning—A case report
Journal of Family Medicine and Primary Care, 2023 Organophosphorus compounds (OPC) are major components of pesticides and nerve gas agents. Self-harm by ingestion of OPC pesticides is one of the common problems encountered in the emergency room (ER), especially in developing countries such as India.
Jenny Joseph +3 more
doaj +1 more source
Mixed cationic liposomes for brain delivery of drugs by the intranasal route: the acetylcholinesterase reactivator 2-PAM as encapsulated drug model [PDF]
Colloids and Surfaces B: Biointerfaces, 171, 358-367 (2018), 2018 New mixed cationic liposomes based on L-{\alpha}-phosphatidylcholine and dihexadecylmethylhydroxyethylammonium bromide (DHDHAB) were designed to overcome the BBB crossing by using the intranasal route. Synthesis and self-assembly of DHDHAB were performed.
arxiv +1 more source
Deformation and breakup of compound droplets in airflow [PDF]
Journal of Colloid and Interface Science, (2024) 653, 517-527, 2023 Hypothesis: Immiscible liquids are commonly used to achieve unique functions in many applications, where the breakup of compound droplets in airflow is an important process. Due to the existence of the liquid-liquid interface, compound droplets are expected to form different deformation and breakup morphologies compared with single-component droplets ...
arxiv +1 more source
Complexation of lithium and sodium cations with B-phosphorylate ethers, modelling terminal groups of organophosphorus podands. An experimental and theoretical study [PDF]
, 1992 The organophosphorus compounds o-Ph2P(O)C6H4OCH3 and Ph2P(O)C2H4OCH3, which are analogs of podands' terminal groups, have been synthesized. The thermodynamic characteristics of their complexation with LiNCS and NaNCS in acetonitrile were obtained by ...
Baulin, V.E. +5 more
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Machine learning for the prediction of safe and biologically active organophosphorus molecules [PDF]
arXiv, 2023 Drug discovery is a complex process with a large molecular space to be considered. By constraining the search space, the fragment-based drug design is an approach that can effectively sample the chemical space of interest. Here we propose a framework of Recurrent Neural Networks (RNN) with an attention model to sample the chemical space of ...
arxiv
Metabolism of profenofos to 4-bromo-2-chlorophenol, a specific and sensitive exposure biomarker. [PDF]
, 2013 Profenofos is a direct acting phosphorothioate organophosphorus (OP) pesticide capable of inhibiting β-esterases such as acetylcholinesterase, butyrylcholinesterase, and carboxylesterase.
Chi, Lai-Har +8 more
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Organophosphorus Chemistry 2018 [PDF]
, 2020 Organophosphorus chemistry is an important discipline within organic chemistry. Phosphorus compounds, such as phosphines, trialkyl phosphites, phosphine oxides (chalcogenides), phosphonates, phosphinates and >P(O)H species, etc., may be important ...
Keglevich, György
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Macrophage TNF-α mediates parathion-induced airway hyperreactivity in guinea pigs. [PDF]
, 2013 Organophosphorus pesticides (OPs) are implicated in human asthma. We previously demonstrated that, at concentrations that do not inhibit acetylcholinesterase activity, the OP parathion causes airway hyperreactivity in guinea pigs as a result of ...
Allison D. Fryer +12 more
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