Study on the Degradation Effect of Three Organophosphorus Hydrolase Mutant on Sarin [PDF]
Organophosphorus hydrolase can effectively degrade organic phosphorus compounds such as sarin. In this study, we constructed a recombinant Bacillus subtilis mutant expressing organophosphorus hydrolase, measured the effect of the mutant on the ...
Gu Qiamin +4 more
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Neurotoxicity in Preclinical Models of Occupational Exposure to Organophosphorus Compounds. [PDF]
Organophosphorus (OPs) compounds are widely used as insecticides, plasticizers, and fuel additives. These compounds potently inhibit acetylcholinesterase (AChE), the enzyme that inactivates acetylcholine at neuronal synapses, and acute exposure to high ...
Voorhees JR +3 more
europepmc +2 more sources
New Enzymatic Targets for Organophosphorus Compounds
It is known that several decarboxylases (aromatic amino acid decarboxylase (AAD), histidine decarboxylase (HD) and glutamate decarboxylase (GD) with different molecular weights catalyze the most important reactions of neurotransmitter and neuromodulator ...
E. N. Efremenko +2 more
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New Trends in Biosensors for Organophosphorus Pesticides
Biosensors are sensitive and can be used as disposable sensors for environmental control. These biosensors are based either on inhibition of acyl cholinesterases acetylcholinesterase or butyrylcholinesterase) by organophosphorus compounds or on ...
Nicole Jaffrezic-Renault
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Lipase-Catalyzed Phospha-Michael Addition Reactions under Mild Conditions
Organophosphorus compounds are the core structure of many active natural products. The synthesis of these compounds is generally achieved by metal catalysis requiring specifically functionalized substrates or harsh conditions.
Yuelin Xu +7 more
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A sweet emergency due to bitter poisoning—A case report
Organophosphorus compounds (OPC) are major components of pesticides and nerve gas agents. Self-harm by ingestion of OPC pesticides is one of the common problems encountered in the emergency room (ER), especially in developing countries such as India.
Jenny Joseph +3 more
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Chemical weapon in the 20th and 21st centuries. Part 3. Organophosphorus chemical warfare agents used until the year 1970. V-group [PDF]
The article contains the knowledge about the V-group of organophosphorus chemical warfare agents, named nerve agents, used since their discovery until the year 1970.
Marcin Kloske, Zygfryd Witkiewicz
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New Cinchona Oximes Evaluated as Reactivators of Acetylcholinesterase and Butyrylcholinesterase Inhibited by Organophosphorus Compounds. [PDF]
For the last six decades, researchers have been focused on finding efficient reactivators of organophosphorus compound (OP)-inhibited acetylcholinesterase (AChE) and butyrylcholinesterase (BChE). In this study, we have focused our research on a new oxime
Katalinić M +5 more
europepmc +2 more sources
Homolytic substitution at phosphorus for C–P bond formation in organic synthesis
Organophosphorus compounds are important in organic chemistry. This review article covers emerging, powerful synthetic approaches to organophosphorus compounds by homolytic substitution at phosphorus with a carbon-centered radical. Phosphination reagents
Hideki Yorimitsu
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Toxic fasciculations–An unusual presentation of organophosphate poisoning
Key Clinical Message The nicotinic symptom in Organo‐Phosphate (OP) poisoning is an unusual presentation in an adult, as in our case of a 38‐year‐old man who also experienced decreased motor power of all limbs and diffuses fasciculation of the tongue and
Lokesh Koumar Sivanandam +3 more
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