Results 71 to 80 of about 3,507 (204)

Protective effects of organoselenium compounds against methylmercury-induced oxidative stress in mouse brain mitochondrial-enriched fractions

Brazilian Journal of Medical and Biological Research, 2011
We evaluated the potential neuroprotective effect of 1-100 µM of four organoselenium compounds: diphenyl diselenide, 3’3-ditri-fluoromethyldiphenyl diselenide, p-methoxy-diphenyl diselenide, and p-chloro-diphenyl diselenide, against methylmercury ...
D.F. Meinerz, M.T. de Paula, B. Comparsi, M.U. Silva, A.E. Schmitz, H.C. Braga, P.S. Taube, A.L. Braga, J.B.T. Rocha, A.L. Dafre, M. Farina, J.L. Franco, T. Posser   +12 more
doaj   +3 more sources

Crystal structure and Hirshfeld surface analysis of (2E,2′E)-1,1′-[selenobis(4,1-phenylene)]bis[3-(4-chlorophenyl)prop-2-en-1-one]

Acta Crystallographica Section E: Crystallographic Communications, 2019
In the title compound, C30H20Cl2O2Se, the C—Se—C angle is 99.0 (2)°, with the dihedral angle between the planes of the attached benzene rings being 79.1 (3)°. The average endocyclic angles (Se—C—C) facing the Se atom are 122.1 (5) and 122.2 (5)°.
Hazem Bouraoui, Youcef Mechehoud, Souheyla Chetioui, Rachid Touzani, Meriem Medjani, Ahmed Benmilat, Ali Boudjada   +6 more
doaj   +1 more source

Synthetic Access to Alkali Metal Selenides via Ball Milling

Zeitschrift für anorganische und allgemeine Chemie, Volume 652, Issue 2, 5 February 2026.
We report the synthesis of alkali metal selenides through reactive ball milling under an argon atmosphere. This mechanochemical pathway is solvent‐free and can be performed at room temperature within minutes to hours. The synthesis of several sodium polyselenides (Na2Sen) and alkali metal selenides (A2Se, A = K, Rb, Cs) is investigated and the received
Anahita I. A. Emminghaus, Josina Papenfuß, Alisha Mertens, Bertold Rasche   +3 more
wiley   +1 more source

Organoselenium-Catalyzed Asymmetric Cyclopropanations of (E)‑Chalcones

We report a new class of chiral tetrahydroselenophene based on (S)-diphenyl­(tetrahydroselenophen-2-yl)­methanol, which was prepared from (R)-3-(3-bromopropyl)-2,2-diphenyloxirane and sodium selenide.
Rong-Jie Chein (1796227), Yu-Hsun Tseng (11529195), Pei-Tung Cheng (11529192)   +2 more
core   +1 more source

Enantioselective Catalysis for the Preparation of Organoselenium Compounds and Applications

, 2014
The peculiar reactivity and the interesting biological properties of chiral organoselenium compounds inspired organic chemists to develop new methodologies for their synthesis.
MARINI, Francesca, STERNATIVO, Silvia, BAGNOLI, Luana   +2 more
core   +1 more source

Harnessing coumarin-thio(seleno)cyanate conjugates: potent In vivo antiproliferative agents targeting carbonic anhydrases

Journal of Enzyme Inhibition and Medicinal Chemistry
We synthesised coumarin-based derivatives bearing thio- and selenocyanates to selectively inhibit tumour-associated carbonic anhydrases (CAs) IX and XII and to exert antiproliferative effects on tumour cells. Structural variations included chalcogen atom
Silvia Alejandra Meza-Ireta, Laura L. Romero-Hernández, Paloma Begines, Simone Giouvannuzi, Adrián Puerta, Aday González-Bakker, Amador Romero-Franco, Pablo Huertas, Alessio Nocentini, José Luis Vega-Báez, Sara Montiel-Smith, José G. Fernández-Bolaños, Maikel Castellano-Pozo, José M. Padrón, Claudiu T. Supuran, Penélope Merino-Montiel, Óscar López   +16 more
doaj   +1 more source

Synthesis of New Organoselenium Compounds: Characterization and Biological Studies

Macedonian Journal of Chemistry and Chemical Engineering, 2020
Two new organoselenium analogs, (3,3'-(1,2-phenylenebis(methylene))bis(2-selenoxo-2,3-dihydro-1H-imidazole-3,1-diyl))bis(methylene) dibenzoate (III) and 3,3'-(1,2-phenylenebis(methylene))bis(1-benzyl-1H-imidazole-2(3H)-selenone) (V), were derived from ...
Nimra Naz, Saima Saqib, Rizwan Ashraf, Muhammad Irfan Majeed, Muhammad Adnan Iqbal   +4 more
doaj   +1 more source

Preparation of Se(IV) Aryltrifluoromethylselenide Dichlorides

European Journal of Organic Chemistry, Volume 29, Issue 1, January 12, 2026.
An efficient synthesis of dichloro(aryl)(trifluoromethyl)‐λ4‐selanes via chlorination of aryl trifluoromethylselenides with SO2Cl2 is reported. The compounds were fully characterized and their stability studied. Density functional theory studies reveal an asynchronous concerted, exergonic pathway, while formation of the Se(VI) derivative is both ...
Julien Paut, Gabriel Goujon, Arnaud De Zordo‐Banliat, Guillaume Dagousset, Jorge Juan Cabrera‐Trujillo, Karinne Miqueu, Emmanuel Magnier, Bruce Pégot   +7 more
wiley   +1 more source

Synthesis, Biological Evaluation, and Molecular Docking of Tellurium‐Containing Benzothiazole Derivatives as Enzyme Inhibitors of DNA Gyrase and Dihydrofolate Reductase

BioMed Research International, Volume 2026, Issue 1, 2026.
Tellurium‐containing heterocycles represent an emerging class of organochalcogen compounds with notable redox properties and antimicrobial potential. Incorporation of tellurium into sulfur‐ and nitrogen‐containing frameworks can enhance biological activity through increased polarizability and favorable noncovalent interactions.
Olha Haleha, Valeriy Pantyo, Nataliya Korol, Elvira Danko, Mykhailo Onysko, Poorani Gurumallesh Prabu   +5 more
wiley   +1 more source

Reduction of Diphenyl Diselenide and Analogs by Mammalian Thioredoxin Reductase Is Independent of Their Gluthathione Peroxidase-Like Activity: A Possible Novel Pathway for Their Antioxidant Activity

Molecules, 2010
Since the successful use of the organoselenium drug ebselen in clinical trials for the treatment of neuropathological conditions associated with oxidative stress, there have been concerted efforts geared towards understanding the precise mechanism of ...
João Batista Teixeira Rocha, Diego Alves, Lisiane Oliveira Porciúncula, Jéssie Haigert Sudati, Caroline Wagner, Andressa Sausen de Freitas, Alessandro de Souza Prestes, Ige Joseph Kade   +7 more
doaj   +1 more source