Results 81 to 90 of about 3,887 (197)

Enantioselective Catalysis for the Preparation of Organoselenium Compounds and Applications

, 2014
The peculiar reactivity and the interesting biological properties of chiral organoselenium compounds inspired organic chemists to develop new methodologies for their synthesis.
MARINI, Francesca, STERNATIVO, Silvia, BAGNOLI, Luana   +2 more
core   +1 more source

Synthesis of New Organoselenium Compounds: Characterization and Biological Studies

Macedonian Journal of Chemistry and Chemical Engineering, 2020
Two new organoselenium analogs, (3,3'-(1,2-phenylenebis(methylene))bis(2-selenoxo-2,3-dihydro-1H-imidazole-3,1-diyl))bis(methylene) dibenzoate (III) and 3,3'-(1,2-phenylenebis(methylene))bis(1-benzyl-1H-imidazole-2(3H)-selenone) (V), were derived from ...
Nimra Naz, Saima Saqib, Rizwan Ashraf, Muhammad Irfan Majeed, Muhammad Adnan Iqbal   +4 more
doaj   +1 more source

Isolation and Structural Characterization of Se‐Hügerschoff Intermediates Derived From 4‐Bromoaniline

Journal of Heterocyclic Chemistry, Volume 63, Issue 6, Page 1004-1009, June 2026.
Isolation and characterization of Se‐brominated Hügerschoff intermediates enable structural and mechanistic insight into seleno‐Hügerschoff cyclization to 2‐aminobenzoselenazoles. ABSTRACT A brominated intermediate within the Hügerschoff reaction has long been postulated but never directly observed.
Adam W. E. Stewart, Tom Fellows, Lucy Li, Craig J. Morton, Glen P. Carter, Jonathan M. White   +5 more
wiley   +1 more source

Harnessing coumarin-thio(seleno)cyanate conjugates: potent In vivo antiproliferative agents targeting carbonic anhydrases

Journal of Enzyme Inhibition and Medicinal Chemistry
We synthesised coumarin-based derivatives bearing thio- and selenocyanates to selectively inhibit tumour-associated carbonic anhydrases (CAs) IX and XII and to exert antiproliferative effects on tumour cells. Structural variations included chalcogen atom
Silvia Alejandra Meza-Ireta, Laura L. Romero-Hernández, Paloma Begines, Simone Giouvannuzi, Adrián Puerta, Aday González-Bakker, Amador Romero-Franco, Pablo Huertas, Alessio Nocentini, José Luis Vega-Báez, Sara Montiel-Smith, José G. Fernández-Bolaños, Maikel Castellano-Pozo, José M. Padrón, Claudiu T. Supuran, Penélope Merino-Montiel, Óscar López   +16 more
doaj   +1 more source

Nitric Oxide‐Generating Poly (allylamine hydrochloride) Coating on Biomedical Titanium Implant

Advanced Materials Interfaces, Volume 13, Issue 10, 19 May 2026.
We report a metal‐free, nitric oxide (NO)‐generating coating in which poly(allylamine hydrochloride) (PAH) is covalently immobilized onto titanium. The coating catalyzes NO generation from the endogenous S‐nitrosothiol GSNO, retains activity after multiple reuse cycles and pH exposures, and maintains endothelial cell viability while modulating ...
Siti Nur Asyura Adzlan, Kang Lin, Shu Geng, Qingqing Fan, Franco Centurion, Zifei Han, Federico Mazur, Rona Chandrawati   +7 more
wiley   +1 more source

Planejamento e síntese de seleno-diidropirimidinonas e avaliação como agentes multi-alvo para o tratamento da doença de Alzheimer [PDF]

, 2014
Tese (doutorado) - Universidade Federal de Santa Catarina, Centro de Ciências Físicas e Matemáticas, Programa de Pós-Graduação em Química, Florianópolis, 2014.Nesta tese de doutorado realizou-se a síntese de uma nova classe de compostos organoselênio ...
Canto, Rômulo Faria Santos
core  

Reduction of Diphenyl Diselenide and Analogs by Mammalian Thioredoxin Reductase Is Independent of Their Gluthathione Peroxidase-Like Activity: A Possible Novel Pathway for Their Antioxidant Activity

Molecules, 2010
Since the successful use of the organoselenium drug ebselen in clinical trials for the treatment of neuropathological conditions associated with oxidative stress, there have been concerted efforts geared towards understanding the precise mechanism of ...
João Batista Teixeira Rocha, Diego Alves, Lisiane Oliveira Porciúncula, Jéssie Haigert Sudati, Caroline Wagner, Andressa Sausen de Freitas, Alessandro de Souza Prestes, Ige Joseph Kade   +7 more
doaj   +1 more source

First chemoenzymatic synthesis of organoselenium amines and amides

, 2008
A series of organoselenium amines have been synthesized and submitted to the enzymatic kinetic resolution by acetylation mediated by CAL-B (Novozym 435) to give the corresponding chiral amides in an enantiomerically pure form.
ANDRADE, Leandro H., SILVA, Alexandre V.
core   +1 more source

Therapeutic Gases in Biomedicine: Updates on Nitric Oxide and Beyond

Advanced Science, Volume 13, Issue 23, 23 April 2026.
Therapeutic gases, including NO, CO, H2S, H2, CO2, O2, and Xe, play vital roles in cellular signaling and repair. This review highlights the emerging carriers and delivery systems that enable controlled, localized gas release for diagnostic and therapeutic applications.
Syed Muntazir Andrabi, Navatha Shree Sharma, Imran Ibn Gani Rather, S. M. Shatil Shahriar, Jingwei Xie   +4 more
wiley   +1 more source

Organoselenium Compounds as Catalysts in Nature and Laboratory

, 2010
The importance of selenium as essential trace element is today generally recognized. The major biological form of this element is represented by the selenocysteine, incorporated into certain protein having redox motifs.
SANTORO, STEFANO, SANTI, Claudio, Benedetta Battistelli, Claudio Santi, B. Battistelli, Stefano Santoro   +5 more
core   +1 more source