Results 51 to 60 of about 4,187 (224)

Cross protection to SARS-CoV-2 variants in hamsters with naturally-acquired immunity

Virology Journal, 2023
Since SARS-CoV-2 was first reported in late 2019, multiple variations of the original virus have emerged. Each variant harbors accumulations of mutations, particularly within the spike glycoprotein, that are associated with increased viral ...
Saina Beitari, Diana Duque, Jegarubee Bavananthasivam, Melissa Hewitt, Jagdeep K. Sandhu, Ita Hadžisejdić, Anh Tran   +6 more
doaj   +1 more source

Vaccine-induced neutralizing antibody responses to seasonal influenza virus H1N1 strains are not enhanced during subsequent pandemic H1N1 infection

Frontiers in Immunology, 2023
The first exposure to influenza is presumed to shape the B-cell antibody repertoire, leading to preferential enhancement of the initially formed responses during subsequent exposure to viral variants.
Petra Mooij, Daniella Mortier, Aafke Aartse, Aafke Aartse, Alexandre B. Murad, Alexandre B. Murad, Ricardo Correia, Ricardo Correia, António Roldão, António Roldão, Paula M. Alves, Paula M. Alves, Zahra Fagrouch, Dirk Eggink, Dirk Eggink, Norbert Stockhofe, Othmar G. Engelhardt, Ernst J. Verschoor, Marit J. van Gils, Marit J. van Gils, Willy M. Bogers, Manuel J. T. Carrondo, Edmond J. Remarque, Gerrit Koopman   +23 more
doaj   +1 more source

Contemporaneous SARS-CoV-2-Neutralizing Antibodies Mediated by N-glycan Shields

Viruses, 2023
Mutations and the glycosylation of epitopes can convert immunogenic epitopes into non-immunogenic ones via natural selection or evolutionary pressure, thereby decreasing their sensitivity to neutralizing antibodies.
Leili Baghaie, Fleur Leroy, Mehdi Sheikhi, Abdollah Jafarzadeh, Myron R. Szewczuk, Abdolkarim Sheikhi   +5 more
doaj   +1 more source

The Effects of Birth Year, Age and Sex on Hemagglutination Inhibition Antibody Responses to Influenza Vaccination

Vaccines, 2018
The first exposure to influenza is thought to impact subsequent immune responses later in life. The consequences of this can be seen during influenza epidemics and pandemics with differences in morbidity and mortality for different birth cohorts.
Ewan P. Plant, Angelia A. Eick-Cost, Hussein Ezzeldin, Jose L. Sanchez, Zhiping Ye, Michael J. Cooper   +5 more
doaj   +1 more source

HLA, Immune Response, and Susceptibility to COVID-19

Frontiers in Immunology, 2021
The severe acute respiratory syndrome caused by Coronavirus 2 (SARS-CoV-2) that appeared in December 2019 has precipitated the global pandemic Coronavirus Disease 2019 (COVID-19).
Fataneh Tavasolian, Mohsen Rashidi, Gholam Reza Hatam, Marjan Jeddi, Ahmad Zavaran Hosseini, Sayed Hussain Mosawi, Sayed Hussain Mosawi, Elham Abdollahi, Robert D. Inman, Robert D. Inman   +9 more
doaj   +1 more source

Review of: "Christ Bearing the Cross: the original antigenic sin of the immune system and its potential role in emerging diseases" [PDF]

, 2023
Rafael Cardoso Maciel Costa Silva
  +6 more sources

Beta RBD boost broadens antibody-mediated protection against SARS-CoV-2 variants in animal models

Cell Reports Medicine, 2021
Summary: Severe acute respiratory syndrome-coronavirus 2 (SARS-CoV-2) variants of concern (VOCs) with resistance to neutralizing antibodies are threatening to undermine vaccine efficacy.
Daniel J. Sheward, Marco Mandolesi, Egon Urgard, Changil Kim, Leo Hanke, Laura Perez Vidakovics, Alec Pankow, Natalie L. Smith, Xaquin Castro Dopico, Gerald M. McInerney, Jonathan M. Coquet, Gunilla B. Karlsson Hedestam, Ben Murrell   +12 more
doaj   +1 more source

Broadly Reactive IgG Responses to Heterologous H5 Prime-Boost Influenza Vaccination Are Shaped by Antigenic Relatedness to Priming Strains

mBio, 2021
Prime-boost vaccinations of humans with different H5 strains have generated broadly protective antibody levels. However, the effect of an individual’s H5 exposure history on antibody responses to subsequent H5 vaccination is poorly understood.
Jiong Wang, Dongmei Li, Sheldon Perry, Shannon P. Hilchey, Alexander Wiltse, John J. Treanor, Mark Y. Sangster, Martin S. Zand   +7 more
doaj   +1 more source

Back to the Future for Influenza Preimmunity—Looking Back at Influenza Virus History to Infer the Outcome of Future Infections

Viruses, 2019
The influenza virus-host interaction is a classic arms race. The recurrent and evolving nature of the influenza virus family allows a single host to be infected several times.
Magen Ellen Francis, Morgan Leslie King, Alyson Ann Kelvin   +2 more
doaj   +1 more source

Christ Bearing the Cross: The Original Antigenic Sin of the Immune System and Its Potential Role in Emerging Diseases [PDF]

, 2023
Ger T. Rijkers, Frans J. van Overveld
openalex   +3 more sources