Results 51 to 60 of about 4,761,340 (218)

Efficient processing of an antigenic sequence for presentation by MHC class I molecules depends on its neighboring residues in the protein [PDF]

, 1991
Processing of endogenously synthesized proteins generates short peptides that are presented by MHC class I molecules to CD8 T lymphocytes. Here it is documented that not only the sequence of the presented peptide but also the residues by which it is ...
Reddehase, Matthias J., Del Val, Margarita, Koszinowski, Ulrich H., Schlicht, Hans-Jürgen, Ruppert, Thomas, Margarita Del Val, Hans-Jürgen Schlicht, Thomas Ruppert, Matthias J. Reddehase, Ulrich H. Koszinowski   +9 more
core   +1 more source

Antigenic variation in African trypanosomes [PDF]

, 2014
Studies on Variant Surface Glycoproteins (VSGs) and antigenic variation in the African trypanosome, Trypanosoma brucei, have yielded a remarkable range of novel and important insights. The features first identified in T.
Horn, David; id_orcid
core   +1 more source

Antigenic variation in Trypanosoma brucei: joining the DOTs [PDF]

, 2008
African trypanosomes, such as <i>Trypanosoma brucei</i>, are protistan parasites that cause sleeping sickness. Though first described more than a century ago, trypanosomes remain a blight on the health of the human population and on the ...
Swiderski, Michal R., J David Barry, McCulloch, Richard, Michal R Swiderski, Chris Stockdale, McCulloch Richard, Barry, J. David, Stockdale Chris, Barry J. David, Stockdale, Chris, Richard McCulloch, Swiderski Michal R   +11 more
core   +1 more source

Yet It Endures: The Persistence of Original Sin

, 2023
Notwithstanding announcements of progress, "international original sin" (the denomination of external debt in foreign currency) remains a persistent phenomenon in emerging markets.
Panizza, Ugo, Eichengreen, Barry, Hausmann, Ricardo   +2 more
core   +1 more source

Back to the Future for Influenza Preimmunity—Looking Back at Influenza Virus History to Infer the Outcome of Future Infections

Viruses, 2019
The influenza virus-host interaction is a classic arms race. The recurrent and evolving nature of the influenza virus family allows a single host to be infected several times.
Magen Ellen Francis, Morgan Leslie King, Alyson Ann Kelvin   +2 more
doaj   +1 more source

Beta RBD boost broadens antibody-mediated protection against SARS-CoV-2 variants in animal models

Cell Reports Medicine, 2021
Summary: Severe acute respiratory syndrome-coronavirus 2 (SARS-CoV-2) variants of concern (VOCs) with resistance to neutralizing antibodies are threatening to undermine vaccine efficacy.
Daniel J. Sheward, Marco Mandolesi, Egon Urgard, Changil Kim, Leo Hanke, Laura Perez Vidakovics, Alec Pankow, Natalie L. Smith, Xaquin Castro Dopico, Gerald M. McInerney, Jonathan M. Coquet, Gunilla B. Karlsson Hedestam, Ben Murrell   +12 more
doaj   +1 more source

Broadly Reactive IgG Responses to Heterologous H5 Prime-Boost Influenza Vaccination Are Shaped by Antigenic Relatedness to Priming Strains

mBio, 2021
Prime-boost vaccinations of humans with different H5 strains have generated broadly protective antibody levels. However, the effect of an individual’s H5 exposure history on antibody responses to subsequent H5 vaccination is poorly understood.
Jiong Wang, Dongmei Li, Sheldon Perry, Shannon P. Hilchey, Alexander Wiltse, John J. Treanor, Mark Y. Sangster, Martin S. Zand   +7 more
doaj   +1 more source

Tierra mía sin nombre, sin América... [PDF]

, 1999
Tierra mía sin nombre, sin América..
AsN, América sin nombre
core   +2 more sources

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source

SARS-CoV-2 Spike Protein Vaccine-Induced Immune Imprinting Reduces Nucleocapsid Protein Antibody Response in SARS-CoV-2 Infection

Journal of Immunology Research, 2022
Immune imprinting or original antigenic sin (OAS) is the process by which the humoral memory response to an antigen can inhibit the response to new epitopes of that antigen originating from a second encounter with the pathogen. Given the situation of the
Juan F. Delgado, Mónica Vidal-Pla, M. Carmen Moya, Mateu Espasa, Antonio Casabella, Manel Seda, Joan Calvet, Jordi Gratacós, Rosa M. Serrano, Pilar Peña   +9 more
doaj   +1 more source