Bivalent COVID-19 Vaccines: Can the Original Antigenic Sin Be Forgiven? [PDF]
Journal of Infectious Diseases, 2023 Joel Blankson
exaly +2 more sources
Analysis of Anti-Influenza Virus Neuraminidase Antibodies in Children, Adults, and the Elderly by ELISA and Enzyme Inhibition: Evidence for Original Antigenic Sin [PDF]
mBio, 2017 Antibody responses to influenza virus hemagglutinin provide protection against infection and are well studied. Less is known about the human antibody responses to the second surface glycoprotein, neuraminidase. Here, we assessed human antibody reactivity
Madhusudan Rajendran +9 more
doaj +2 more sources
The Wages of Original Antigenic Sin [PDF]
Emerging Infectious Diseases, 2010 David M. Morens +2 more
doaj +2 more sources
Original antigenic sin priming of influenza virus hemagglutinin stalk antibodies [PDF]
Proceedings of the National Academy of Sciences of the United States of America, 2020 Valerie le Sage, Scott Hensley
exaly +2 more sources
Original Antigenic Sin and Pandemic (H1N1) 2009 [PDF]
Emerging Infectious Diseases, 2010 Amesh A. Adalja, D.A. Henderson
doaj +2 more sources
A speed limit on serial strain replacement from original antigenic sin. [PDF]
Proc Natl Acad Sci U S AMany pathogens evolve to escape immunity, yet it remains difficult to predict whether immune pressure will lead to diversification, serial replacement of one variant by another, or more complex patterns.
McGough L, Cobey S.
europepmc +2 more sources
Original antigenic sin in dengue - Hoskins effect
APIK Journal of Internal Medicine, 2023 Dengue is a mosquito-borne viral infection found in tropical and subtropical climates worldwide, mostly in urban and semiurban areas. The virus responsible for causing dengue is called dengue virus. There are four dengue virus serotypes, implying that it
Vasantha Kamath, Nisha Davy Olakkengi
doaj +1 more source
From Original Antigenic Sin to the Universal Influenza Virus Vaccine [PDF]
Trends in Immunology, 2018 Anna-Karin E Palm +2 more
exaly +2 more sources
Earliest infections predict the age distribution of seasonal influenza A cases
eLife, 2020 Seasonal variation in the age distribution of influenza A cases suggests that factors other than age shape susceptibility to medically attended infection.
Philip Arevalo +3 more
doaj +1 more source
Serological Cross-Reactivity in Zoonotic Flaviviral Infections of Medical Importance
Antibodies, 2023 Flaviviruses are enveloped RNA viruses from the family Flaviviridae that comprise many important human pathogenic arboviruses such as Yellow Fever, Dengue, and Zika viruses.
Priscilla Gomes da Silva +4 more
doaj +1 more source