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Serological Cross-Reactivity in Zoonotic Flaviviral Infections of Medical Importance

open access: yesAntibodies, 2023
Flaviviruses are enveloped RNA viruses from the family Flaviviridae that comprise many important human pathogenic arboviruses such as Yellow Fever, Dengue, and Zika viruses.
Priscilla Gomes da Silva   +4 more
doaj   +1 more source

Genesis and pathogenesis of the 1918 pandemic H1N1 influenza A virus [PDF]

open access: yes, 2014
The source, timing, and geographical origin of the 1918–1920 pandemic influenza A virus have remained tenaciously obscure for nearly a century, as have the reasons for its unusual severity among young adults.
A. Rambaut   +29 more
core   +2 more sources

Heterologous prime-boost vaccination with H3N2 influenza viruses of swine favors cross-clade antibody responses and protection [PDF]

open access: yes, 2017
The emergence of multiple novel lineages of H1 and H3 influenza A viruses in swine has confounded control by inactivated vaccines. Because of substantial genetic and geographic heterogeneity among circulating swine influenza viruses, one vaccine strain ...
Claes, Gerwin   +8 more
core   +2 more sources

Pre-Pandemic Cross-Reactive Immunity against SARS-CoV-2 among Central and West African Populations

open access: yesViruses, 2022
For more than two years after the emergence of COVID-19 (Coronavirus Disease-2019), significant regional differences in morbidity persist. These differences clearly show lower incidence rates in several regions of the African and Asian continents.
Marc Souris   +16 more
doaj   +1 more source

Heterotypic Neuraminidase Antibodies Against Different A(H1N1) Strains are Elicited after Seasonal Influenza Vaccination

open access: yesVaccines, 2019
Neuraminidase (NA) content is not standardized in current seasonal influenza vaccines; neither anti-NA antibodies (anti-NA Abs) are measured nor is it well-defined as a correlate of humoral protection. In this work, the presence of NA1 antibodies against
Jose Manuel Mendez-Legaza   +2 more
doaj   +1 more source

Generation and selection of anti-flagellin monoclonal antibodies useful for serotyping Salmonella enterica [PDF]

open access: yes, 2013
In developing countries, bacterial acute gastroenteritis continues to be an important cause of morbidity and mortality among young children. Salmonellosis constitutes a major cause of infectious enteritis worldwide, most of them associated to the ...
Algorta, Gabriela   +8 more
core   +2 more sources

Pandemic Paradox: Early Life H2N2 Pandemic Influenza Infection Enhanced Susceptibility to Death during the 2009 H1N1 Pandemic. [PDF]

open access: yes, 2018
Recent outbreaks of H5, H7, and H9 influenza A viruses in humans have served as a vivid reminder of the potentially devastating effects that a novel pandemic could exert on the modern world.
Alain Gagnon   +11 more
core   +3 more sources

Cross protection to SARS-CoV-2 variants in hamsters with naturally-acquired immunity

open access: yesVirology Journal, 2023
Since SARS-CoV-2 was first reported in late 2019, multiple variations of the original virus have emerged. Each variant harbors accumulations of mutations, particularly within the spike glycoprotein, that are associated with increased viral ...
Saina Beitari   +6 more
doaj   +1 more source

Immunogenicity of NS4b dengue 3 virus mimotope presented to the immune system as multiple antigen peptide system [PDF]

open access: yes, 2013
The availability of random peptide libraries displayed on bacteriophage (RPL) has provided a powerful tool for selecting sequences that mimic binding properties of natural antigen epitopes (mimotopes). These mimotopes can be used for vaccine design, drug
Acosta, Armando   +11 more
core   +2 more sources

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