Results 41 to 50 of about 4,761,340 (218)

Heterotypic Neuraminidase Antibodies Against Different A(H1N1) Strains are Elicited after Seasonal Influenza Vaccination

open access: yesVaccines, 2019
Neuraminidase (NA) content is not standardized in current seasonal influenza vaccines; neither anti-NA antibodies (anti-NA Abs) are measured nor is it well-defined as a correlate of humoral protection. In this work, the presence of NA1 antibodies against
Jose Manuel Mendez-Legaza   +2 more
doaj   +1 more source

Pre-Pandemic Cross-Reactive Immunity against SARS-CoV-2 among Central and West African Populations

open access: yesViruses, 2022
For more than two years after the emergence of COVID-19 (Coronavirus Disease-2019), significant regional differences in morbidity persist. These differences clearly show lower incidence rates in several regions of the African and Asian continents.
Marc Souris   +16 more
doaj   +1 more source

Original antigenic sin: A comprehensive review

open access: yes, 2020
The concept of “original antigenic sin” was first proposed by Thomas Francis, Jr. in 1960. This phenomenon has the potential to rewrite what we understand about how the immune system responds to infections and its mechanistic implications on how vaccines
Gershwin M.E.   +5 more
core   +1 more source

Cross protection to SARS-CoV-2 variants in hamsters with naturally-acquired immunity

open access: yesVirology Journal, 2023
Since SARS-CoV-2 was first reported in late 2019, multiple variations of the original virus have emerged. Each variant harbors accumulations of mutations, particularly within the spike glycoprotein, that are associated with increased viral ...
Saina Beitari   +6 more
doaj   +1 more source

Vaccine-induced neutralizing antibody responses to seasonal influenza virus H1N1 strains are not enhanced during subsequent pandemic H1N1 infection

open access: yesFrontiers in Immunology, 2023
The first exposure to influenza is presumed to shape the B-cell antibody repertoire, leading to preferential enhancement of the initially formed responses during subsequent exposure to viral variants.
Petra Mooij   +23 more
doaj   +1 more source

Antigenic drift in H5N1 avian influenza virus in poultry is driven by mutations in major antigenic sites of the hemagglutinin molecule analogous to those for human influenza virus [PDF]

open access: yes, 2011
H5N1 highly pathogenic avian influenza virus has been endemic in poultry in Egypt since 2008, notwithstanding the implementation of mass vaccination and culling of infected birds.
Arafa, Abdel   +19 more
core   +1 more source

Contemporaneous SARS-CoV-2-Neutralizing Antibodies Mediated by N-glycan Shields

open access: yesViruses, 2023
Mutations and the glycosylation of epitopes can convert immunogenic epitopes into non-immunogenic ones via natural selection or evolutionary pressure, thereby decreasing their sensitivity to neutralizing antibodies.
Leili Baghaie   +5 more
doaj   +1 more source

The Effects of Birth Year, Age and Sex on Hemagglutination Inhibition Antibody Responses to Influenza Vaccination

open access: yesVaccines, 2018
The first exposure to influenza is thought to impact subsequent immune responses later in life. The consequences of this can be seen during influenza epidemics and pandemics with differences in morbidity and mortality for different birth cohorts.
Ewan P. Plant   +5 more
doaj   +1 more source

Diabetes with hypertension as risk factors for adult dengue hemorrhagic fever in a predominantly dengue serotype 2 epidemic: a case control study. [PDF]

open access: yes, 2012
BACKGROUND: Dengue hemorrhagic fever (DHF) is a severe form of dengue, characterized by bleeding and plasma leakage. A number of DHF risk factors had been suggested.
Kee Seng Chia   +41 more
core   +2 more sources

HLA, Immune Response, and Susceptibility to COVID-19

open access: yesFrontiers in Immunology, 2021
The severe acute respiratory syndrome caused by Coronavirus 2 (SARS-CoV-2) that appeared in December 2019 has precipitated the global pandemic Coronavirus Disease 2019 (COVID-19).
Fataneh Tavasolian   +9 more
doaj   +1 more source

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