Results 41 to 50 of about 4,187 (224)

A speed limit on serial strain replacement from original antigenic sin. [PDF]

Proc Natl Acad Sci U S A
McGough L, Cobey S.
europepmc   +3 more sources

Original antigenic sin: A potential double-edged effect for vaccine improvement

Biomedicine and Pharmacotherapy
Original antigenic sin (OAS) influences the immune response to subsequent infections with related variants following initial pathogen exposure. This phenomenon is characterized by cross-reactivity, which, although it may worsen infections, also provides a degree of protection against immune evasion caused by variations.
Xiaohong Zhang, Jiangchen Yao, Jing Liu   +2 more
exaly   +3 more sources

Original antigenic sin priming of influenza virus hemagglutinin stalk antibodies. [PDF]

Proc Natl Acad Sci U S A, 2020
Arevalo CP, Le Sage V, Bolton MJ, Eilola T, Jones JE, Kormuth KA, Nturibi E, Balmaseda A, Gordon A, Lakdawala SS, Hensley SE.   +10 more
europepmc   +3 more sources

SARS-CoV-2 infections elicit higher levels of original antigenic sin antibodies compared to SARS-CoV-2 mRNA vaccinations [PDF]

, 2021
Anderson EM, Eilola T, Goodwin E, Bolton MJ, Gouma S, Goel RR, Painter MM, Apostolidis SA, Mathew D, Dunbar D, Fiore D, Brock A, Weaver J, Millar JS, DerOhannessian S, The UPenn COVID Processing Unit, Greenplate AR, Frank I, Rader DJ, Wherry EJ, Hensley SE.   +20 more
europepmc   +2 more sources

What about the original antigenic sin of the humans versus SARS-CoV-2? [PDF]

Med Hypotheses, 2020
Roncati L, Palmieri B.
europepmc   +3 more sources

Original antigenic sin in Japanese encephalitis vaccination [PDF]

, 2020
Filippo Tatullo
openaire   +2 more sources

Earliest infections predict the age distribution of seasonal influenza A cases

eLife, 2020
Seasonal variation in the age distribution of influenza A cases suggests that factors other than age shape susceptibility to medically attended infection.
Philip Arevalo, Huong Q McLean, Edward A Belongia, Sarah Cobey   +3 more
doaj   +1 more source

Serological Cross-Reactivity in Zoonotic Flaviviral Infections of Medical Importance

Antibodies, 2023
Flaviviruses are enveloped RNA viruses from the family Flaviviridae that comprise many important human pathogenic arboviruses such as Yellow Fever, Dengue, and Zika viruses.
Priscilla Gomes da Silva, José Augusto Seixas dos Reis, Marcio Nogueira Rodrigues, Quézia da Silva Ardaya, João Rodrigo Mesquita   +4 more
doaj   +1 more source

Pre-Pandemic Cross-Reactive Immunity against SARS-CoV-2 among Central and West African Populations

Viruses, 2022
For more than two years after the emergence of COVID-19 (Coronavirus Disease-2019), significant regional differences in morbidity persist. These differences clearly show lower incidence rates in several regions of the African and Asian continents.
Marc Souris, Léon Tshilolo, Daniel Parzy, Line Lobaloba Ingoba, Francine Ntoumi, Rachel Kamgaing, Moussa Ndour, Destin Mbongi, Balthazar Phoba, Marie-Anasthasie Tshilolo, René Mbungu, Martin Samuel Sosso, Nadine Fainguem, Tandakha Ndiaye Dieye, Massamba Sylla, Pierre Morand, Jean-Paul Gonzalez   +16 more
doaj   +1 more source

Heterotypic Neuraminidase Antibodies Against Different A(H1N1) Strains are Elicited after Seasonal Influenza Vaccination

Vaccines, 2019
Neuraminidase (NA) content is not standardized in current seasonal influenza vaccines; neither anti-NA antibodies (anti-NA Abs) are measured nor is it well-defined as a correlate of humoral protection. In this work, the presence of NA1 antibodies against
Jose Manuel Mendez-Legaza, Raúl Ortiz de Lejarazu, Ivan Sanz   +2 more
doaj   +1 more source