Assembly of Helicobacter pylori initiation complex is determined by sequence-specific and topology-sensitive DnaA-oriC interactions [PDF]
In bacteria, chromosome replication is initiated by binding of the DnaA initiator protein to DnaA boxes located in the origin of chromosomal replication (oriC). This leads to DNA helix opening within the DNA-unwinding element.
Mielke, T. +4 more
core +1 more source
The Bacillus subtilis primosomal protein DnaD untwists supercoiled DNA [PDF]
The essential Bacillus subtilis DnaD and DnaB proteins have been implicated in the initiation of DNA replication. Recently, DNA remodeling activities associated with both proteins were discovered that could provide a link between global or local nucleoid
Zhang, Wenke +3 more
core +1 more source
Although the mechanisms that precisely time initiation of chromosome replication in bacteria remain unclear, most clock models are based on accumulation of the active initiator protein, DnaA-ATP.
Prassanna Rao (5560376) +4 more
core +1 more source
Identification Of Elements Essential For Replication Origin Activity In Escherichia coli
The increasing number of drug resistant pathogenic bacteria has created a growing health care crisis. Solving the crisis will require a number of solutions, among them being development of new antibiotics that target novel cell processes.
Rao, Prassanna
core
Analysis Of A Functional Heterologous Chromosomal Replication Origin Transplant In E. coli
To ensure that all cells replicate their genomes faithfully before they divide, the initiation step of chromosome replication must be tightly regulated during the cell cycle.
Kadam, Rohit Pradip
core
ORISOM - A System of Outcome Prediction
Abstract This paper presents a comprehensive analysis of the Outcome Recurrence & Informational Subset Oscillation Mapping (ORISOM-F) framework, a novel system for sequential outcome prediction. Developed iteratively across two distinct AI environments—initially in ChatGPT for foundational concepts and subsequently optimized in Claude AI for ...
openaire +3 more sources
Editorial: Bacterial transcription factors and the cell cycle, volume II. [PDF]
Morigen +4 more
europepmc +1 more source
Editorial: Bacterial Transcription Factors and the Cell Cycle. [PDF]
Morigen, Glinkowska M, Xie J.
europepmc +1 more source
The Replicative DnaE Polymerase of Bacillus subtilis Recruits the Glycolytic Pyruvate Kinase (PykA) When Bound to Primed DNA Templates. [PDF]
Holland A +3 more
europepmc +1 more source
ORACLE-QC – ORISOM Relational Axiom Language Computational Engine for Quantum Computing
A Formal Specification of a Relational, Axiom-Grounded Architecture for Post-Numerical Computational Intelligence Abstract ORACLE-QC (ORISOM Relational Axiom Language Computational Engine for Quantum Computing) is a formally specified, architecturally novel computational framework that emerges from the operational analysis work conducted within ...
openaire +3 more sources

