Results 11 to 20 of about 10,116 (169)

Joint TOS/OMA/OAC expert guidance statement on the pharmacological management of United States adults with overweight or obesity using the GRADE approach. [PDF]

Obes Pillars
Guidance recommendations by TOS/OMA/OAC for the use of obesity medications to treat obesity and its complications. ABSTRACT Background Obesity affects over 40% of US adults, with severe obesity on the rise. Despite recognition of obesity as a chronic disease, it remains underdiagnosed and undertreated.
Alexander L, Purnell JQ, Burridge K, Cornier MA, Golden A, Horn DB, Look M, Nadglowski J, Ávila-Oliver C, Novillo F, Rojas-Gómez AM, Hussey B, Salas XR.   +12 more
europepmc   +2 more sources

Prevalence of Therapeutic Inertia in the Management of Overweight and Obesity in Patients With a Diagnosis of Type 2 Diabetes Who Are Followed up by Primary Care Physicians. [PDF]

Obes Sci Pract
ABSTRACT Introduction Information on therapeutic inertia (TI) in weight loss in people with type 2 diabetes (T2D) is limited. Objective To describe the prevalence of TI in the management of overweight/obesity in people with T2D undergoing primary care program (PCP) follow‐up and weight changes according to the prescribed treatment.
Aschner P, Henao-Carrillo D.
europepmc   +2 more sources

Melt Amorphisation of Orlistat with Mesoporous Silica Using a Supercritical Carbon Dioxide: Effects of Pressure, Temperature, and Drug Loading Ratio and Comparison with Other Conventional Amorphisation Methods

Pharmaceutics, 2020
The aim of this work was to develop an amorphous orlistat-loaded mesoporus silica formulation using the melt-amorphisation by supercritical fluid (MA-SCF) and to investigate the effects of pressure and temperature on the pharmaceutical properties of the ...
Heejun Park, Kwang-Ho Cha, Seung Hyeon Hong, Sharif Md Abuzar, Eun-Sol Ha, Jeong-Soo Kim, Min-Soo Kim, Sung-Joo Hwang   +7 more
doaj   +1 more source

Comparison of Efficacy of Fermented Garlic and Orlistat (Lipase Inhibitor) in Obesity Management Using an Experimental Rodent Model

Foods, 2023
Background: Black garlic, also known as fermented garlic, is a useful food that may have therapeutic benefits. The aim of this study was to analyze the impact of fermented garlic and orlistat therapy on obese rats. Methods: A total of 40 male albino rats
Mavra Javed, Waqas Ahmed, Azmatullah Khan, Imtiaz Rabbani   +3 more
doaj   +1 more source

Atorvastatin versus tetrahydrolipstatin in male patients with dyslipidemia: A systematic review and meta-analysis [PDF]

Journal of Pharmacy & Pharmacognosy Research
Context: Atorvastatin is typically used in the treatment of dyslipidemia. However, the interest in using anti-obesity medications such as orlistat has grown rapidly as obesity is one of the variables associated with dyslipidemia.
Nur Aini Hasan, Viskasari Pintoko Kalanjati, Kusuma Eko Purwantari, Abdurachman Abdurachman, Muhammad Miftahussurur   +4 more
doaj   +1 more source

Effect of orlistat and aquatic extract of Rosmarinus officinalis leaves in histopathological changes in kidney of albino rat [PDF]

Iraqi Journal of Veterinary Sciences, 2022
This study investigated the effects of orlistat and rosemary extract on kidney tissue when combined with a high-fat diet, as well as the association between these treatments and body weight, blood lipid profile, and oxidative stress status in male rats ...
Alya A. Al-Safo, Liqaa H. AlDulaimi
doaj   +1 more source

Effect of Allium sativum extract in combination -with orlistat on insulin resistance and disrupted metabolic hormones in high fat diet induced obese rats

Scientific African, 2021
Obesity has increased in epidemic proportions globally and the current antiobesity drugs have treatment limitations which further reduce treatment benefits.
Ogunyemi Bukola Caroline, Osaretin A.T. Ebuehi, Oshanupin Adeola Cecilia, Ogunyemi Adewale Kayode   +3 more
doaj   +1 more source

Acute Oxalate Nephropathy Associated with Orlistat: A Case Report with a Review of the Literature

Case Reports in Nephrology, 2013
Orlistat is a gastrointestinal lipase inhibitor used for weight reduction in obese individuals. Enteric hyperoxaluria caused by orlistat leads to oxalate absorption. Acute oxalate nephropathy is a rare complication of treatment with orlistat.
Dhara Chaudhari, Conchitina Crisostomo, Charles Ganote, George Youngberg   +3 more
doaj   +1 more source

Orlistat in polycystic ovarian syndrome reduces weight with improvement in lipid profile and pregnancy rates

Journal of Human Reproductive Sciences, 2014
Background: The effects of exercise, metformin, and orlistat on anthropometric parameters, lipid profile, endocrine parameters, and ovulation in polycystic ovarian syndrome (PCOS) women were compared.
Pratap Kumar, Shweta Arora
doaj   +1 more source

Effect of orlistat on liver fat content in patients with nonalcoholic fatty liver disease with obesity: assessment using magnetic resonance imaging-derived proton density fat fraction

Therapeutic Advances in Gastroenterology, 2019
Background: The liver effect of orlistat as a weight control treatment in patients with nonalcoholic fatty liver disease (NAFLD) with obesity remains undetermined.
Junzhao Ye, Yanqin Wu, Fuxi Li, Tingfeng Wu, Congxiang Shao, Yansong Lin, Wei Wang, Shiting Feng, Bihui Zhong   +8 more
doaj   +1 more source