Results 131 to 140 of about 87,049 (284)
Characterization of bovine liver ornithine aminotransferase
, 1986 소의 간으로부터 ornithine aminotransferase를 ammonium-sulfate침전, DEAE-cellulose chromatography, DEAE-Sepha-dex chromatography, Sephadex G-200 gel filtration chromatography를 이용하여 6.4%의 회수율로 209배 정제하였다.
박광숙
core +1 more source
Association Characteristics and Potential Mechanisms of Aging, Gut Microbiota, and Hearing Loss
Integrative Zoology, EarlyView.The study found that aging leads to unchanged gut microbiota alpha diversity but an increase in Bacteroidetes and a decrease in Firmicutes at the phylum level, with specific genera, species, and functional pathways co‐associated with aging and hearing loss. Through constructing a microbe‐metabolite network, it revealed the mechanism by which protective
Cheng Cheng +7 more
wiley +1 more source
, 2017 © 2017 Informa UK Limited, trading as Taylor & Francis Group Introduction: Current trials for ß-cell transplantation have been hindered by poor cell viability and function post-transplantation.
R. Negrulj (23323585) +5 more
core
Brain Pathology, EarlyView.Brain viral reservoirs were undetectable in neonatal SIV during the first 3 days post infection; antiretroviral therapy (ART) at 3 dpi prevented brain reservoir seeding and normalized metabolic function, highlighting the necessity of very early treatment to protect the developing CNS.
Li Ma +12 more
wiley +1 more source
The Pathological Roles of Cationic Amino Acid Transporters (CATs) in Cancer
Cancer Science, EarlyView.CAT family transporters (SLC7A1–SLC7A4) coordinate arginine allocation within the tumor microenvironment, thereby regulating cancer metabolism, mTORC1 signaling, immune responses, and metastatic progression. Emerging evidence supports context‐dependent roles for SLC7A1–SLC7A3, whereas the physiological and pathological functions of SLC7A4 remain poorly
Thant Thant Myo Oo, Yasuhiro Saito
wiley +1 more source
Cell Proliferation, EarlyView.Polyamine metabolism is innervation responsive and involved in denervation‐induced muscle atrophy. Inhibition of polyamine metabolism attenuates muscle atrophy by restraining proteolysis and preserving MuSCs homeostasis. Denervation‐induced activation of FAP‐derived FGF7 drives premature MuSCs activation, while DFMO suppresses this paracrine cue to ...
Mingming Zhang +9 more
wiley +1 more source
L-Ornithine Decarboxylase from Hafnia alvei Has a Novel L-Ornithine Oxidase Activity
, 1997 A novel activity producing y-aminobutyric acid (GABA) from L-ornithine in the presence of NAD(P)+ was found in the crude extract of L-ornithine-induced Hafnia alvei, in addition to L-ornithine decarboxylase (ODC) activity.
Hiroshi Nagatomo +5 more
core
The tryptophan prenyltransferase ComQ from Bacillus subtilis 168 can prenylate daptomycin at Trp1
The FEBS Journal, EarlyView.ComQ168 from Bacillus subtilis 168 catalyzes C‐terminal tryptophan farnesylation of ComX to generate a competence‐inducing pheromone. Recombinant ComQ168 also modifies cyclic peptides, including Daptomycin, likely at the N‐terminal tryptophan. Structural modeling highlights a C‐terminal binding region, supporting substrate promiscuity and establishing ...
Yanli Xu +2 more
wiley +1 more source
L-ornithine decarboxylase from Evernia prunastri.
, 2014 L-ornithine decarboxylase (EC 4.1.1.17) was 88-fold purified from E. prunastri thallus with an overall yield of 14.5%. The enzyme developed maximum activity when lichen thalli were floated on 40 mML-ornithine.
Legaz, María Estrella +1 more
core
4‐1BBL Suppresses Anti‐Inflammatory Responses by Regulating Metabolic Reprogramming of Macrophages
Immunology, EarlyView.4‐1BB ligand (4‐1BBL) is known to promote sustained pro‐inflammatory responses in macrophages. This study demonstrates that 4‐1BBL acts as a negative regulator of anti‐inflammatory macrophage responses. Genetic deletion or pharmacological inhibition of 4‐1BBL significantly enhanced the phosphorylation of IL‐4R‐proximal JAK1 and STAT6, elevating the ...
Young Jun Kang
wiley +1 more source