Results 71 to 80 of about 2,711,207 (206)

Inonotus obliquus Ameliorates Metabolic Dysfunction and Attenuates Obesity by Enriching Enterococcus casseliflavus

Food Frontiers, Volume 7, Issue 4, July 2026.
Inonotus obliquus mitigates obesity through the targeted enrichment of intestinal Enterococcus casseliflavus (EC). EC facilitates thermogenesis in adipose tissues, augments energy expenditure, enhances systemic metabolic homeostasis, and diminishes low‐grade inflammation.
Xiao Sun, Xuliang Wei, Meng Dong, Haoyang Liu, Tengyu Zhu, Yangming Zhang, Longhui Wang, Yongchun Li, Hongde Xu   +8 more
wiley   +1 more source

Studies relevant to the biosynthesis of orotic acid.

, 1967
The biosynthesis of orotic acid is briefly reviewed. This investigation is concerned with elucidating the stereo-chemical requirements of dihydro-orotic dehydrogenases the enzyme involved in the final stage of the biosynthesiss, with respect to the ...
Atkinson, Michael.
core  

Differential labeling with orotic acid and uridine in compensatroy renal hypertrophy

, 1975
Using [5-3H]orotic acid and [5-3H]uridine as precursors, we compared the efficiency of labeling and the localization of labeled RNA during compensatory hypertrophy of the mouse kidney.
JA Caulfield, RA Malt, JS Ross, D Malamud   +3 more
core   +1 more source

First Revision of the Guidelines for the Diagnosis and Management of Remethylation Disorders

Journal of Inherited Metabolic Disease, Volume 49, Issue 4, July 2026.
ABSTRACT This guideline summarizes diagnostic and therapeutic approaches based on a systematic literature review and evidence evaluation using the GRADE methodology. Given the limited high‐quality data, expert consensus was additionally obtained through a modified Delphi process.
Giorgia Olivieri, Andrea Bordugo, Birute Burnyte, Alessandro Costetti, Maria‐Luz Couce, Luisa Diogo, Francois Feillet, D. Sean Froese, Benedetta Greco, Jean‐Louis Gueant, Luciana Hannibal, Friederike Hörster, Viktor Kožich, Giancarlo La Marca, Irini Manoli, Fanny Mochel, Lorenzo Orazi, Belén Pérez, Manuel Schiff, Bernd C. Schwahn, Ida Schwartz, Karolina M. Stepien, Jolanta Sykut‐Cegielska, Trine Tangeraas, Rolf H. Zetterström, Carlo Dionisi‐Vici, Martina Huemer   +26 more
wiley   +1 more source

The effect of liposomal composition with encapsulated potassium orotate on the macrophage link of immunity in the treatment of wounds

Аграрная наука Евро-Северо-Востока
In veterinary medicine, treatment of wounds is one of the most important areas. A possible way to solve the problem of wound treatment is to activate the body's own protective reserves, primarily the immune system.
V. V. Mosyagin, V. S. Popov, G. F. Ryzhkova   +2 more
doaj   +1 more source

Diagnostic value of urinary orotic acid levels: applicable separation methods

, 2002
Urinary orotic acid determination is a useful tool for screening hereditary orotic aciduria and for differentiating the hyperammonemia disorders which cannot be readily diagnosed by amino acid chromatography, thus reducing the need for enzyme ...
Carlo Crifò, SALERNO, Costantino, CRIFO', Carlo, Costantino Salerno   +3 more
core   +1 more source

Galleria mellonella as a drug discovery model to study oxidative stress

Scientific Reports
Biological systems are equipped with endogenous antioxidant defence mechanisms against reactive oxygen species (ROS). Accumulation of ROS usually overwhelms this, creating pathologic effects.
Fred Jonathan Edzeamey, Zenouska Ramchunder, Ronan R. McCarthy, Sara Anjomani Virmouni   +3 more
doaj   +1 more source

Rare forms of nephrolithiasis

Pediatria i Medycyna Rodzinna, 2019
Inborn errors of metabolism that may lead to calculus formation within the urinary tract include: adenine phosphoribosyltransferase deficiency, xanthine oxidase deficiency, orotic aciduria (acidosis) type I and alkaptonuria.
Piotr Skrzypczyk, Małgorzata Pańczyk-Tomaszewska   +1 more
doaj   +1 more source

High-performance liquid chromatographic determination of orotic acid as its methyl derivative in human urine

, 1997
Described is a method for the determination of orotic acid as its methyl ester in human urine. The method involves the use of solid-phase extraction to isolate pyrimidines from urine and derivatization with methanol and sulfuric acid, followed by ...
Rufini, S., Micheletti, A, Sposito, M, GAMBELUNGHE, Cristiana, Fioravanti, A, Flaviani, M   +5 more
core   +1 more source

Clinical and molecular characteristics of 69 Chinese patients with ornithine transcarbamylase deficiency

Orphanet Journal of Rare Diseases, 2020
Background This study aimed to describe the clinical and biochemical features of Chinese patients with ornithine transcarbamylase deficiency (OTCD), and to investigate the mutation spectrum of OTC gene and their potential correlation with phenotype ...
Deyun Lu, Feng Han, Wenjuan Qiu, Huiwen Zhang, Jun Ye, Lili Liang, Yu Wang, Wenjun Ji, Xia Zhan, Xuefan Gu, Lianshu Han   +10 more
doaj   +1 more source