Results 181 to 190 of about 68,732 (285)
A survey of downstream applications of evolutionary scale modeling protein language models
Quantitative Biology, Volume 14, Issue 1, March 2026.Abstract The evolutionary scale modeling (ESM) series is promising to revolutionize protein science and engineering through large language models (LLMs), providing a robust framework for understanding the relationships among sequences, structures, and functions of proteins.
Qingyu Yang, Jiale Yu, Jie Zheng
wiley +1 more source
Nuclear receptors as therapeutic targets in metabolic and cardiovascular disorders. [PDF]
iScienceLi F, Chen Q, Dai Y, Lu L.
europepmc +1 more source
“You Are Safe Now”: Migrant Youth Constructions of Safety and Schooling in the U.S.
Anthropology &Education Quarterly, Volume 57, Issue 1, March 2026.ABSTRACT Drawing on multisited ethnographic research with migrant families from Brazil, El Salvador, Guatemala, and Honduras who were detained, separated, or endured prolonged transit due to US immigration policies, we articulate how ideas of “relational safety” are situated in relationships with people, place, and time. Contrasting abundant literature
Michelle J. Bellino, Gabrielle Oliveira
wiley +1 more source
Biomedical Chromatography, Volume 40, Issue 2, February 2026.ABSTRACT The investigational molecule bexicaserin is a highly selective 5‐HT2C superagonist currently in Phase 3 clinical studies for the treatment of seizures associated with developmental and epileptic encephalopathies (DEEs). To facilitate its clinical development, a simple LC–MS/MS method was developed and validated for the quantitative estimation ...
Raja Reddy Kallem +5 more
wiley +1 more source
Health Science Reports, Volume 9, Issue 2, February 2026.ABSTRACT Background and Aims Lower income European countries (LIECs) have more limited financial resources to cover high‐cost technologies in rare diseases than higher income European countries (HIECs). Our study explores how treatment recommendations in myelodysplastic syndrome (MDS) can be supported in LIECS by transferring real‐world evidence (RWE ...
Zoltán Kaló +25 more
wiley +1 more source
Critical Evaluation of the Role of Transcription Factor RAR-Orphan Receptor-γt in the Development of Chronic Inflammatory Dermatological Diseases: A Promising Therapeutic Target. [PDF]
BiomoleculesPramanik A, Mondal P, Bhattacharyya S.
europepmc +1 more source
International Journal of Cancer, Volume 158, Issue 3, Page 775-789, 1 February 2026.What's new? Circadian rhythm disruption potentially fuels prostate cancer progression. The mechanisms and signaling molecules contributing to hormonal tumorigenesis, however, remain largely undefined. In this study, circadian expression patterns of core‐circadian controlled genes (CCCGs) and nuclear receptors (NRs) were investigated in advanced ...
Ria Chopra +4 more
wiley +1 more source
The emerging role of DNA methylation in the pathogenicity of bacterial pathogens. [PDF]
J BacteriolMa Y-x, Wang X-d, Li X-m.
europepmc +1 more source
Journal of Cachexia, Sarcopenia and Muscle, Volume 17, Issue 1, February 2026.ABSTRACT Background Sarcopenia, an important complication of chronic obstructive pulmonary disease (COPD), is significantly associated with increased mortality. Systemic inflammation is an important trigger of COPD‐related skeletal muscle dysfunction. Calprotectin is a damage‐associated molecular pattern involved in the inflammatory response, but its ...
Liwei Liao +9 more
wiley +1 more source